SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | OPENING ADDRESS |
| Discussion Leader: Rob Clarke (University of Manchester) |
8:00 pm - 9:00 pm | Edison Liu (Genome Institute, Singapore)
"Genomic dissection of estrogen receptor biology" |
9:00 pm - 9:10 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MODELS OF MOUSE DEVELOPMENT AND CANCER |
9:00 am - 9:10 am | Discussion Leader: Paul Edwards (Pathology, Cambridge) |
9:10 am - 9:50 am | Bill Muller (McMaster University, Hamilton)
"Integrin mediated signal transduction in transgenic mouse models of human breast cancer" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break / Group Photo |
10:30 am - 11:05 am | Jos Jonkers (Netherlands Cancer Institute, Amsterdam)
"Advanced mouse mammary tumour models" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:50 am | Barry Gusterson (University of Glasgow)
"Molecular systems Regulating Terminal End Bud Growth and Directional Guidance" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Short Talk: Nicolas Kenney (Hampton University, Virginia)
"The coordination of cell fate decisions during mouse mammary gland development" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | BREAST CANCER SUSCEPTIBILITY AND PREVENTION |
5:30 pm - 5:40 pm | Discussion Leader: Julian Peto (Institute of Cancer Research, London) |
5:40 pm - 6:15 pm | Thea Tlsty (University of California)
"Biology of the 'at risk' Breast" |
6:15 pm - 6:25 pm | Discussion |
6:25 pm - 7:00 pm | Tony Howell (University of Manchester)
"Breast Cancer Susceptibility and Prevention" |
7:00 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Short Talk: Paraic Kenny (LBNL, Berkeley, California)
"Targeting TACE-Dependent Growth Factor Shedding in Breast Cancer" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ADULT MAMMARY GLAND DEVELOPMENT |
9:00 am - 9:10 am | Discussion Leader: Dan Medina (Baylor College of Medicine, Houston) |
9:10 am - 9:50 am | Bernd Groner (Georg-Speyer Haus, Frankfurt)
"Genes Regulating Mammary Gland Development" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Jane Visvader (Melbourne)
"Generation of a Functional Mammary Gland from a Single Stem Cell" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | John Stingl (University of Cambridge, Cambridge)
"Phenotypic and functional characterization of mouse mammary epithelial stem cells” |
11:45 am - 11:55 am | Discussion |
11:55 am - 12.20 pm | Matt Smalley (Breakthrough Breast Cancer, London)
"Mammary stem cells and steroid receptors" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | HORMONE AND GROWTH FACTOR SIGNALLING PATHWAYS |
5:30 pm - 5:40 pm | Discussion Leader: Jeff Rosen (Baylor College of Medicine, Houston) |
5:40 pm - 6:15 pm | Chris Ormandy (Garvan Institute, Sydney)
"Prolactin signaling" |
6:15 pm - 6:25 pm | Discussion |
6:25 pm - 7:00 pm | Steffi Osterreich (Baylor College of Medicine, Houston)
"Estrogen Receptor Corepressors in Normal Mammary Gland Development and Breast Cancer" |
7:00 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Short Talk: Bryan Welm (University of California at San Francisco)
"Targeting Mammary Gland Stem Cells with Viruses for Analysis of Gene Function during Mammary Development" |
7:25 pm - 7:30 pm | Discussion |
8:00 pm | Dinner |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | DEVELOPMENTAL SIGNALLING PATHWAYS |
9:00 am - 9:10 am | Discussion Leader: Bob Callahan (NCI, Bethesda) |
9:10 am - 9:50 am | Cathrin Brisken (ISREC, Lausanne, Switzerland)
"Genetic models of development and cancer" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Caroline Alexander (McArdle Cancer Research Labs, Madison)
"A New Culture Platform for Studying Mammary Epithelial Cell Interactions" |
11:00 am - 11:10 am | Discussion |
11:10 am - 11:40 am | Keith Brennan (University of Manchester)
"Notch Receptor Signalling in the Breast" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:20 pm | Salvatore Pece (Milan, Italy)
"Loss of Numb in Breast Cancer" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | LACTATION AND INVOLUTION |
5:30 pm - 5:40 pm | Discussion Leader: Steve Anderson (University of Colorado, Denver) |
5:40 pm - 6:15 pm | Olav Oftedal (Smithsonian Institute, Washington)
"The evolution of lactation" |
6:15 pm - 6:25 pm | Discussion |
6:25 pm - 7:00 pm | Peggy Neville (University of Colorado, Denver)
"Lactational programming" |
7:00 pm - 7:10 pm | Discussion |
7:10 pm - 7:25 pm | Short Talk: Pepper Schedin (University of Colorado Health Sciences Center)
"Microenvironment of the Involuting Mammary Gland Activates Tumor Metastasis: A New Target for Chemoprevention?" |
7:25 pm - 7:30 pm | Discussion |
7:30 pm - 8:00 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
8:00 pm | Dinner |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MODELS OF HUMAN DEVELOPMENT AND CANCER |
9:00 am - 9:10 am | Discussion Leader: Christine Clarke (Sydney) |
9:10 am - 9:50 am | Joan Brugge (Boston)
"Morphogenesis and Oncogenesis in 3D Culture Models and In Vivo" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Ole-William Petersen (University of Copenhagen)
"In search of a stem cell hierarchy in the human breast and its relevance to breast cancer evolution" |
11:10 am - 11:20 am | Discussion |
11:20 am - 12:00 pm | Charlotte Kuperwasser (Boston)
"Modelling the Human Breast In Vivo" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Short Talk: Mohamed Bentires-Alj (Harvard)
"A role for the scaffolding adapter GAB2 in breast cancer" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | KEYNOTE ADDRESS |
5:30 pm - 6:00 pm | Introductory remarks: Rob Clarke (University of Manchester) |
6:00 pm - 7:00 pm | Gil Smith (NIH, Bethesda)
"Mammary Stem Cells: Shibboleths of Mammary Development" |
7:00 pm - 8:00 pm | Closing Remarks / Reception |
8:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |