| SATURDAY |
| 1:30 pm - 4:30 pm | Arrival and Check-in |
| 3:00 pm - 3:15 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:15 pm - 4:00 pm | Regulation of Mammary Gland Development and Function |
| Discussion Leader: Rachel Zwick (Yale University) |
| 3:15 pm - 3:30 pm | Elizabeth Kass (Memorial Sloan-Kettering Cancer Center)
"Effect of Tissue-Specific and Genetic Changes on Homology-Directed Repair in the Mouse Mammary Gland"
|
| 3:30 pm - 3:40 pm | Discussion |
| 3:40 pm - 3:55 pm | Lenha Mobuchon (Institut National de la Recher)
"Effect of a 48h Food Deprivation on the Expression of the Lactating Goat Mammary miRNome Obtained by Deep Sequencing"
|
| 3:55 pm - 4:00 pm | Discussion |
| 4:00 pm - 5:30 pm | Poster Session I |
| 5:30 pm - 7:30 pm | Breast Cancer Growth and Progression |
| Discussion Leader: Ania Wronski (Tufts University) |
| 5:30 pm - 5:50 pm | Micka Bertucci (Monash University)
"Investigating the Role of Myotubularin Related Protein 4 (MTMR4) in Breast Cancer"
|
| 5:50 pm - 6:00 pm | Discussion |
| 6:00 pm - 6:20 pm | Kassondra Meyer (University of Wisconsin-Madison)
"REST Loss Induces a Growth Advantage in Breast Tumor Cells Through Upregulation of the Insulin Receptor Substrate 1"
|
| 6:20 pm - 6:30 pm | Discussion |
| 6:30 pm - 6:50 pm | Sarah Hein (Baylor College of Medicine)
"Parity Reprograms the Mammary Epithelium to Lower the Apoptotic Anticancer Barrier to Oncogenic Mutations"
|
| 6:50 pm - 7:00 pm | Discussion |
| 7:00 pm - 7:20 pm | David Gallego-Ortega (Garvan Institute)
"Elf5-Forced Lactation Induces Lung Metastasis in the MMTV-PyMT Mouse Mammary Model"
|
| 7:20 pm - 7:30 pm | Discussion |
| 8:00 pm | Dinner |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Breast Cancer Stem Cells and Metastasis |
| Discussion Leader: Milan Obradovic (Friedrich Miescher Institute for Cancer Research) |
| 9:00 am - 9:20 am | Caitlin Rugani (University of Wisconsin-Madison)
"A Lumen-Based In Vitro Model to Study Individual Cancer Cell Behavior in Normal Mammary Ducts"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Sarah Boyle (University of Adelaide)
"The Important Role of Chemokine Receptor CCR7 in Regulation of Breast Cancer Stem Cells"
|
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Devon Lawson (University of California, San Francisco)
"Single-Cell Analysis Reveals a Distinct Stem Cell Program in Early Human Metastatic Breast Cancer Cells"
|
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Bruno Simoes (Institute of Cancer Science, Manchester)
"Endocrine Therapy-Induced Cancer Stem Cell Activity in Patient-Derived Breast Samples is Dependent upon Notch Signaling"
|
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Funding Cutting-Edge Research |
| Discussion Leader: Ana Luisa Correia (Friedrich Miescher Institute for Cancer Research) |
| 1:30 pm - 2:20 pm | Victoria Seewaldt (Duke University)
"Dramatic Grant Writing Revisited: A.K.A. How to Write a Compelling Aims Page (and How Not to Annoy the Reviewers with Over-the-Top Purple Prose)"
|
| 2:20 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
