| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Normal Mammary Gland Microenvironment |
| Discussion Leader: Rachel Zwick (Yale University, USA) |
| 3:45 pm - 4:00 pm | Zuzana Koledova (Masaryk University, Faculty of Medicine, Czech Republic)
"A Pleiotropic Role for FGF Signaling in Mammary Gland Stroma" |
| 4:00 pm - 4:05 pm | Discussion |
| 4:05 pm - 4:20 pm | Gerard Tarulli (University of Adelaide, Australia)
"Unraveling an Identity for the Androgen Receptor-Expressing Mammary
Epithelial Cell" |
| 4:20 pm - 4:25 pm | Discussion |
| 4:25 pm - 4:30 pm | General Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Breast Cancer Initiation and
Progression |
| Discussion Leader: Ania Wronski (Tufts University, USA) |
| 7:30 pm - 7:50 pm | Nicholas Brady (University of Minnesota, USA)
"Macrophage-Specific Deletion of STAT5 Disrupts Normal Mammary Gland
Development and Accelerates Mammary Tumorigenesis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Albana Gattelli (Friedrich Miescher Institute for Biomedical Research, Switzerland)
"Aberrant Ret Receptor Expression in the Mammary Gland Causes Tumors and
Developmental Defects" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Holly Holliday (Garvan Institute of Medical Research, Australia)
"Transcriptional Regulation of Mammary Gland Lineage Commitment by
Inhibitor of Differentiation 4 (Id4)" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Teresa Monkkonen (Baylor College of Medicine, USA)
"Local Ptch1 Mediates Mammary Gland Morphogenesis and Histology in the
Epithelium and Stroma Respectively, While Systemic Stromal Ptch1 Regulates
Ductal Elongation" |
| 9:20 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Breast Cancer Stem Cells and
Metastasis |
| Discussion Leader: Emily Powell (The University of Texas MD Anderson Cancer Center, USA) |
| 9:00 am - 9:20 am | Alison Obr (Rutgers University, USA)
"The Role of Insulin/IGF Signaling in Inflammation and Metastasis of Basal-Like Breast Cancer" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Daniel Smith (The University of Texas MD Anderson Cancer Center, USA)
"Prophylactic Cranial Irradiation Reduces the Incidence of Brain
Metastasis in a Mouse Model of Metastatic, HER2 Positive Inflammatory Breast Cancer" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Praveena Thiagarajan (Cleveland Clinic, USA)
"Interrogating Cellular Heterogeneity and Self-Renewal in Triple Negative
Breast Cancer" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Reema Wahdan-Alaswad (University of Colorado, USA)
"Metformin Inhibits TGF-β-Mediated Tumor Promotion and Stem Enrichment in
Mesenchymal-Stem Like/Claudin-Low Subtype of Triple Negative Breast Cancers" |
| 10:50 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Component: Life After the PhD |
| Discussion Leaders: Jessica Finlay-Schultz (University of Colorado, Anschutz Medical Campus, USA) and Lara Lacerda (The University of Texas MD Anderson Cancer Center, USA) |
| 1:30 pm - 2:25 pm | Sarah Cardozo Duncan (Career Strategist, USA)
"Networking: Now What Do I Say?" |
| 2:25 pm - 2:30 pm | Discussion |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
