Saturday
1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Growth and Survival in the Developing and Diseased Gland
Discussion Leader: Renee Van Amerongen (University of Amsterdam, The Netherlands)
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:35 pm
Priska Auf der Maur (University Hospital Basel / University of Basel, Switzerland)
"Forward Genetic Screen to Identify Resistance Mechanisms Towards BYL719 Treatment in Breast Cancer"
3:35 pm - 3:40 pm
Discussion
3:40 pm - 3:55 pm
Olivia McGinn (University of Colorado Anschutz Medical Campus, USA)
"Cytokeratin 5/Beta-Catenin Interaction and Crosstalk in Maintaining Breast Cancer Stem Cells"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Interactions Between Mammary Epithelium and Its Environment
Discussion Leader: Kara Britt (Peter MacCallum Cancer Centre, Australia)
5:30 pm - 5:50 pm
Lindsey Seldin (Vanderbilt University, USA)
"Mammary Myoepithelial Cells Respond to Damage by Altering Cell Fate In Vivo "
5:50 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
Hendrik Johannes Kuiken (Harvard Medical School, USA)
"Characterization of Functional Heterogeneity and In Vivo Dynamics of Subclonal Cell Populations Derived from the Triple-Negative Breast Cancer Cell Line MDA-MB-468"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
Sarah Boyle (Centre for Cancer Biology, Australia)
"ROCK-Education of Mammary Tumor Fibroblasts Enhances Their Malignant Phenotype to Create a Tumor-Permissive Microenvironment"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
Hendrika Duivenvoorden (La Trobe Institute for Molecular Science, La Trobe University, Australia)
"Searching for Suppressors of Early Breast Cancer Cell Invasion Using 3D Models"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Alan Elder (University of Colorado Anschutz Medical Campus, USA)
"A Novel Role for Semaphorin 7A in Normal Mammary and Tumor-Associated Lymphangiogenesis"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Novel Tools and Approaches in Mammary Gland Biology
Discussion Leader: Christina Scheel (Helmholtz Center Munich, Germany)
9:00 am - 9:20 am
Karsten Bach (University of Cambridge, United Kingdom)
"The Study of Mammary Epithelial Cell Differentiation Dynamics and Breast Cancer Development by Single Cell RNA Sequencing"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Genevieve Dall (Peter MacCallum Cancer Centre, Australia)
"Implicating the Estrogen Receptor Positive Luminal Progenitors as Driving ER+ Breast Cancer Development"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
Ben Atwell (University of Arizona, USA)
"Targeting Sorting Nexins to Treat ERBB-Dependent Breast Cancer"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Qiang Lan (Institute of Biotechnology, University of Helsinki, Finland)
"Mammary Gland Branching Morphogenesis: What Can Tissue Recombination Experiments Teach Us?"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Nonappa Nonappa (Aalto University, Finland)
"Novel Preclinical Model for Personalised Breast Cancer Therapy"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Strategies to Transition to Research Independence or Branch into Industry
This mentoring session will focus on some of the strategies and planning that can be done early in a research career so postgraduate students and postdocs are well positioned to make the important transition to research independence or industry.
Discussion Leaders: Russell Hovey (University of California, Davis, USA) and Johanna Wagner (University of Zurich, Switzerland)
1:30 pm - 2:30 pm
Panel Discussion
Strategies and Planning Tips for Your Next Career Steps in Academia or Industry
Kara Britt (Peter MacCallum Cancer Centre, Australia)
Christina Scheel (Helmholtz Center Munich, Germany)
Renee Van Amerongen (University of Amsterdam, The Netherlands)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
