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Mammary Gland Biology (GRS)

Gordon Research Seminar

Branching Out: Exploring the Cellular Processes Driving Mammary Gland Development and Disease

May 26 - 27, 2018

Chairs

and

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Mammary Gland Biology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is to cover many aspects of mammary gland development and disease, bringing together cutting edge young investigators in these areas. The goal of the meeting will be to stimulate discussion that connects a fundamental understanding of mammary gland development with the alterations that occur during tumorigenesis.

This meeting will also include a special mentoring session to advise graduate students and post-docs on how to plan early for making a successful transition to research independence.

Related Meeting

This GRS will be held in conjunction with the "Mammary Gland Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:30 pm - 4:30 pm	Arrival and Check-in
3:00 pm - 3:15 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm	Growth and Survival in the Developing and Diseased Gland Discussion Leader:
3:15 pm - 3:20 pm	Introduction by Discussion Leader
3:20 pm - 3:35 pm	"Forward Genetic Screen to Identify Resistance Mechanisms Towards BYL719 Treatment in Breast Cancer"
3:35 pm - 3:40 pm	Discussion
3:40 pm - 3:55 pm	"Cytokeratin 5/Beta-Catenin Interaction and Crosstalk in Maintaining Breast Cancer Stem Cells"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 5:30 pm	Poster Session
5:30 pm - 7:30 pm	Interactions Between Mammary Epithelium and Its Environment Discussion Leader:
5:30 pm - 5:50 pm	"Mammary Myoepithelial Cells Respond to Damage by Altering Cell Fate In Vivo"
5:50 pm - 6:00 pm	Discussion
6:00 pm - 6:20 pm	"Characterization of Functional Heterogeneity and In Vivo Dynamics of Subclonal Cell Populations Derived from the Triple-Negative Breast Cancer Cell Line MDA-MB-468"
6:20 pm - 6:30 pm	Discussion
6:30 pm - 6:45 pm	"ROCK-Education of Mammary Tumor Fibroblasts Enhances Their Malignant Phenotype to Create a Tumor-Permissive Microenvironment"
6:45 pm - 6:50 pm	Discussion
6:50 pm - 7:05 pm	"Searching for Suppressors of Early Breast Cancer Cell Invasion Using 3D Models"
7:05 pm - 7:10 pm	Discussion
7:10 pm - 7:25 pm	"A Novel Role for Semaphorin 7A in Normal Mammary and Tumor-Associated Lymphangiogenesis"
7:25 pm - 7:30 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Novel Tools and Approaches in Mammary Gland Biology Discussion Leader:
9:00 am - 9:20 am	"The Study of Mammary Epithelial Cell Differentiation Dynamics and Breast Cancer Development by Single Cell RNA Sequencing"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Implicating the Estrogen Receptor Positive Luminal Progenitors as Driving ER+ Breast Cancer Development"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Targeting Sorting Nexins to Treat ERBB-Dependent Breast Cancer"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Mammary Gland Branching Morphogenesis: What Can Tissue Recombination Experiments Teach Us?"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"Novel Preclinical Model for Personalised Breast Cancer Therapy"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Strategies to Transition to Research Independence or Branch into Industry This mentoring session will focus on some of the strategies and planning that can be done early in a research career so postgraduate students and postdocs are well positioned to make the important transition to research independence or industry. Discussion Leaders: and
1:30 pm - 2:30 pm	Panel Discussion Strategies and Planning Tips for Your Next Career Steps in Academia or Industry
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

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Mammary Gland Biology

June 8 - 13, 2025

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