Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Epithelial-Stromal Interactions in the Mammary Gland and Disease
Discussion Leader: Michelle Williams (University of Colorado Anschutz Medical Campus, USA)
3:45 pm - 3:55 pm
Maria Cristina Miranda Vergara (University of Notre Dame, USA)
"Stromal Matrix Metalloproteinase 3 (MMP3) Regulates Immune Cell Recruitment to Inhibit Primary Tumor Burden in Breast Cancer"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
Vasudha Srivastava (University of California, San Francisco, USA)
"Physical Mechanisms for Oncogene-Induced Breakdown in Mammary Tissue Structure"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Sarah Tarullo (University of Colorado Anschutz Medical Campus, USA)
"Matrix Remodeling by Semaphorin 7a Promotes Invasion in Postpartum Breast Cancer"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cancer Stem Cells and Tumorigenesis/Mammary Gland Development
Discussion Leader: Jessica Elswood (Texas A&M University, USA)
7:30 pm - 7:45 pm
Thu Truong (University of Minnesota, USA)
"Steroid Receptor Co-Activators PELP1 and SRC-3 Cooperate to Drive Luminal Breast Cancer Stemness"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Olivia McGinn (University of Colorado Anschutz Medical Campus, USA)
"CK5 and β-Catenin Interact to Promote Breast Cancer Stem Cell Properties"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Sirinapa Sribenja (Roswell Park Comprehensive Cancer Center, USA)
"Foxa1 Deletion in Mouse Mammary Gland Increases Proportion of Luminal Progenitor Cells: A Link to Racial Disparity in Breast Cancer"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Cole McQueen (Texas A&M University, USA)
"PER2 Regulation of Mammary Gland Development"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Gillian Wilson (University of Glasgow, United Kingdom)
"CCR1 Is an Important Regulator of Branching Morphogenesis in the Mammary Gland"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Haris Girish (Baylor College of Medicine, USA)
"The Intestinal Microbiome of High and Low-Lactation Capacity Inbred Mice Changes with Strain and Is Shaped by Pregnancy and Lactation"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Immune Microenvironment Regulation in Mammary Gland Biology
Discussion Leader: Emily Irey (University of Minnesota, USA)
9:00 am - 9:15 am
Garhett Wyatt (Texas A&M University, USA)
"Cross-Talk Between SIM2s and NFkB Regulates Cyclooxygenase 2 Expression in Breast Cancer"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Danielle Renner (University of Minnesota, USA)
"Macrophage Contributions to Mammary Tumor Metastasis"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Katelyn Kozma (SickKids, Canada)
"Defining the Role of Stat3 Signaling in the Metastatic Dissemination"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Michelle Williams (University of Colorado Anschutz Medical Campus, USA)
"Reversal of an Epithelial to Mesenchymal Program by miR-200c Reveals a Pro-Metastatic Cytokine Profile in Triple Negative Breast Cancer"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Genevra Kuziel (University of Wisconsin-Madison, USA)
"Inflammation-Induced CD11b+ Cells Contribute to Mammary Tumor Fibrosis"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Manjusha Ghosh (University of Regensburg, Germany)
"Identification of Metastatic Founder Cells by Single Cell Phylogenies"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Teresa Monkkonen (University of California, San Francisco, USA)
1:30 pm - 2:30 pm
Panel Discussion
Designing a Game Plan for the Next Step in Your Career
Jerrica Breindel (Quinnipiac University, USA)
Traci Lyons (University of Colorado Anschutz Medical Campus, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
