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Mammary Gland Biology (GRS)

Gordon Research Seminar

Cellular Signaling and the Environment in Mammary Gland Development in Disease

June 8 - 9, 2019
Chairs and
Jordan Hotel at Sunday River
27 Grand Circle
Newry, Maine, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Mammary Gland Biology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The primary focus of this meeting is on cutting-edge research in mammary gland development and disease, bringing together young investigators active in these research areas. The goal is to encourage discussion that connects the fundamental processes during mammary gland development with alterations that occur during tumorigenesis.

This meeting will also include a special mentoring session to advise graduate students and post-docs on how make a successful career transition.

Related Meeting

This GRS will be held in conjunction with the "Mammary Gland Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Epithelial-Stromal Interactions in the Mammary Gland and Disease
Discussion Leader:
3:45 pm - 3:55 pm
"Stromal Matrix Metalloproteinase 3 (MMP3) Regulates Immune Cell Recruitment to Inhibit Primary Tumor Burden in Breast Cancer"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Physical Mechanisms for Oncogene-Induced Breakdown in Mammary Tissue Structure"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Matrix Remodeling by Semaphorin 7a Promotes Invasion in Postpartum Breast Cancer"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cancer Stem Cells and Tumorigenesis/Mammary Gland Development
Discussion Leader:
7:30 pm - 7:45 pm
"Steroid Receptor Co-Activators PELP1 and SRC-3 Cooperate to Drive Luminal Breast Cancer Stemness"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"CK5 and β-Catenin Interact to Promote Breast Cancer Stem Cell Properties"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Foxa1 Deletion in Mouse Mammary Gland Increases Proportion of Luminal Progenitor Cells: A Link to Racial Disparity in Breast Cancer"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"PER2 Regulation of Mammary Gland Development"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"CCR1 Is an Important Regulator of Branching Morphogenesis in the Mammary Gland"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"The Intestinal Microbiome of High and Low-Lactation Capacity Inbred Mice Changes with Strain and Is Shaped by Pregnancy and Lactation"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Immune Microenvironment Regulation in Mammary Gland Biology
Discussion Leader:
9:00 am - 9:15 am
"Cross-Talk Between SIM2s and NFkB Regulates Cyclooxygenase 2 Expression in Breast Cancer"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"Macrophage Contributions to Mammary Tumor Metastasis"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Defining the Role of Stat3 Signaling in the Metastatic Dissemination"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Reversal of an Epithelial to Mesenchymal Program by miR-200c Reveals a Pro-Metastatic Cytokine Profile in Triple Negative Breast Cancer"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Inflammation-Induced CD11b+ Cells Contribute to Mammary Tumor Fibrosis"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"Identification of Metastatic Founder Cells by Single Cell Phylogenies"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader:
1:30 pm - 2:30 pm
Panel Discussion
Designing a Game Plan for the Next Step in Your Career
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes

Contributors

National Institutes of Health - National Institute of Environmental Health Sciences
National Institutes of Health - National Cancer Institute
University of Minnesota - Masonic Cancer Center
Rutgers University - Office of Research and Economic Development (ORED)
Rutgers University - Rutgers Cancer Institute of New Jersey

Funding for this conference was made possible (in part) by 1R13CA239577-01 from the National Cancer Institute and National Institute of Environmental Health Sciences. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Conference Links

Conference History Mammary Gland Biology
Additional Fee Info

Mammary Gland Biology
June 8 - 13, 2025


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