Non-Cell-Autonomous Mechanisms in Normal Mammary Gland and Breast Cancer Development

June 1 - 2, 2024

Chairs

and

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Conference Description

The Mammary Gland Biology GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

The 2024 Mammary Gland Biology GRS will highlight cutting-edge edge research that investigates how mammary epithelial cells interact with other mammary and non-mammary cells, with the goal of further understanding normal mammary gland biology and breast cancer development and metastasis. This seminar will also feature novel tools and innovative applications of conventional approaches for studying these interactions. Lastly, this GRS will also dedicate a mentoring session to equip attendees with invaluable strategies for navigating various career paths and to help nurture the next generation of scientists in this field.

Related Meeting

This GRS will be held in conjunction with the "Mammary Gland Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:00 pm - 3:15 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm	Keynote Session: Understanding the Publication Process at Nature Journals Discussion Leader:
3:15 pm - 3:50 pm	"How to Publish in Scientific Journals"
3:50 pm - 4:00 pm	Discussion
4:00 pm - 5:30 pm	Poster Session
5:30 pm - 7:30 pm	Normal Mammary Gland Biology to Breast Cancer Initiation Discussion Leader:
5:30 pm - 5:45 pm	"Determining the Immunological Basis of Pregnancy-Induced Protection Against Breast Cancer"
5:45 pm - 5:50 pm	Discussion
5:50 pm - 6:05 pm	"Pregnancy Restricts an Age-Driven Accumulation of Hybrid Cells in the Mammary Gland"
6:05 pm - 6:10 pm	Discussion
6:10 pm - 6:25 pm	"Lipids and Collagen: Important Actors in the Development of the Mammary Gland"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:45 pm	"Sympathetic Nerves Modulate Mammary Gland Differentiation via Hormone-Sensing Progenitors"
6:45 pm - 6:50 pm	Discussion
6:50 pm - 7:05 pm	"Investigating the Microenvironment of Breast Cancer Brain Metastases"
7:05 pm - 7:10 pm	Discussion
7:10 pm - 7:30 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Molecular Signaling and Inflammation in Breast Cancer Metastasis Discussion Leader:
9:00 am - 9:15 am	"Modulation of Tumour-Promoting Inflammation in Breast Cancer by Oncostatin M cytokine: Implications in Metastasis, Extracellular Matrix Remodeling and Immune Suppression"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Effects of Childbirth on Clinical Findings of Breast Cancer Metastasis"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Quantifying Diversity in Triple Negative Breast Cancer Genomics"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"PIK3CA H1047R Mutation Activates Intercellular Tissue-Scale PI3K/AKT and MAPK/ERK Pathway Crosstalk to Drive Excessive Proliferation and Therapy Tolerance in Mammary Epithelium"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Brca1 Haploinsufficiency Promotes Early Tumor Onset and Epigenetic Alterations in a Mouse Model of Hereditary Breast Cancer"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"Distal Inflammatory Priming of Normal Mammary Tissue by the Gut Microbiome Drives Breast Tumor Metastasis via Metabolic Dysregulation"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Guidance on Being an Effective Mentor and Mentee Discussion Leader:
1:30 pm - 1:45 pm	"Histone Acetyltransferases, P300 and CBP, Regulate Collective Epithelial Migration in Normal Mammary Gland Development and Breast Cancer Invasion"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:25 pm	"The Art of Mentoring and Being Mentored"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Conference Links

Conference History Mammary Gland Biology

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