| SUNDAY |
| 2:00 pm - 6:00 pm | Registration and check-in |
| 6:00 pm | Dinner |
| 7:00 pm - 9:00 pm | Registration and check-in |
| 7:30 pm - 9:30 pm | CHEMICAL ECOLOGY |
| 7:30-7:40 | Alison Butler
WelcomeConference Policies |
| Discussion Leader: Dale Nagle, University of Mississippi and William Fenical, Scripps Institution of Oceanography |
| 7:40 pm - 8:20 pm | Valerie Paul, University of Guam
"Chemical Ecology of Benthic Marine Cyanobacteria" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Niels Lindquist, University of North Carolina at Chapel Hill
"Small Partners Packing Powerful Punches: Investigations of Defensive Microbial-Invertebrate Symbioses" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Julia Kubanek, Georgia Institute of Technology
"Multiple functions and Ecological Consequences of Chemical Signals in the Sea" |
| 9:20 pm - 9:30 pm | Discussion |
| 9:30 pm -11:00 pm | Chair's Welcoming Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am -12:30 pm | DRUG DISCOVERY |
| Discussion Leaders: John Faulkner, Scripps Institution of Oceanography and Amy Wright, Harbor Branch |
| 9:00 am - 9:40 am | Ray Andersen, University of British Columbia
"Marine Natural Products, A Rich Source of Chemical Diversity for Drug Discovery" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:30 am | Kenneth Bair, Novartis Institute for Biomedicine
"From Natural Products Extracts to Anti-Cancer Drugs" |
| 10:30 am - 10:40 am | Discussion |
| 10:40 am - 11:00 am | Coffee |
| 11:00 am - 11:20 am | Photograph |
| 11:20 am - 11:50 am | Carol Bewley, NIDDK-NIH
"Marine Natural Product Inhibitors in Infectious Diseases" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | David Burgoyne, Inflazyme Pharmaceuticals Ltd.,
"IPL576,092: Marine Natural Product to Clinical Lead" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SYMBIOSIS AND BIOSYNTHESIS |
| Discussion Leaders: David Sherman, University of Minnesota and Bradley Moore, University of Arizona |
| 7:30 pm - 7:40 pm | Introduction to PKS by the Discussion Leaders |
| 7:40 pm - 8:10 pm | Joern Piel, Max Planck Institute of Chemical Ecology
"Polyketide Biosynthesis in an Unculturable Bacterial Symbiont" |
| 8:10 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:50 pm | Margo Haygood, Scripps Institution of Oceanography
"Evidence for Involvement of Bacterial Symbionts in Biosynthesis of Bryostatins in the Marine Bryozoan, Bugula neritina" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Ute Hentschel, Universitat Würzburg
"Molecular Evidence for a Uniform Microbial Community in Sponges from Different Oceans" |
| 9:20 pm - 9:30 pm | Discussion |
| 9:30 pm -11:00 pm | Poster Session #1 continued |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | BIOSYNTHESIS OF MARINE NATURAL PRODUCTS |
| Discussion Leader: Robert S. Jacobs, UC Santa Barbara |
| 9:00 am - 9:40 am | Seiichi Matsuda, Rice University
"Tinkering with Terpene Biosynthesis" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Russ Kerr, Florida Atlantic University
"The Pseudopterosins - Elucidation of the Biosynthetic Origin, Discovery of Anti-inflammatory Intermediates and Proposal of a Biotechnological Production Method" |
| 10:20 am - 10:30 am | Discussion |
| 10:30am - 11:00 am | Coffee |
| SYNTHESIS OF MARINE NATURAL PRODUCTS |
| Discussion Leader: Tadeusz Molinski, UC Davis |
| 11:00 am - 11:40 am | Larry Overman, UC Irvine
"Recent Studies in Marine Natural Products Total Synthesis" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:20 pm | Jim Panek, Boston University
"Studies Toward the Synthesis of Marine Natural Products" |
| 12:20 pm -12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30pm | NATURAL PRODUCTS FROM MARINE MICROORGANISMS |
| Discussion Leader: Margo Haygood, Scripps Institution of Oceanography |
| 7:30 pm - 8:55 pm | William Fenical, Scripps Institution of Oceanography
"Marine Microorganisms as a Biomedical Source: Are They Unculturable or Uncultured?" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:25 pm | Phil Crews, UC Santa Cruz
"Sponges and Associated Microorganisms: The Road to New Chemotypes and Biological Tools" |
| 8:25 pm - 8:30 pm | Discussion |
| APPLICATIONS OF EMERGING METHODOLOGIES |
| Discussion Leader: Mark Zabriskie, Oregon State University |
| 8:30 pm - 9:00 pm | Martin Keller, Diversa
"Natural Product Discovery: What is next?" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:25 pm | Nada Zein, Novartis Institute for Functional Genomics
"From Nature to the Chip, Successes and Trepidations" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm -11:00 pm | Poster Session #2 continued |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm: | BIOLOGICAL ACTIVITIES, APPLICATIONS AND PHARMACOLOGY OF MARINE NATURAL PRODUCTS |
| Discussion Leader: William Gerwick, Oregon State University and John Blunt, University of Canterbury |
| 9:00 am - 9:40 am | Isaac Pessah, UC Davis
"Novel Probes to Elucidate Intracellular Calcium Signaling From Marine> Sponges" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | David Rowley, University of Rhode Island
"New Marine Peptide Inhibitors of the Herpes simplex Virus' |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am - 10:50 am | Coffee |
| 10:50 am - 11:10 am | Dale Nagle, The University of Mississippi
"Targeting gene expression for the discovery of new tumor-selective chemotherapeutic agents" |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:40 am | Jose Maria Sanchez-Puelles
"Molecular Mechanisms of Marine Drugs"
|
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:20 pm | Christine Salomon, University of Minnesota
"The exploration of symbiotic bacteria as a source of polyketide tedanolide derivatives in three marine sponges" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #3 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MNP ISOLATION AND STRUCTURE ELUCIDATION |
| Discussion Leader: Eric Schmidt, University of Utah and Brent Copp, University of Aukland |
| 7:30 pm - 8:00 pm | Nobuhiro Fusetani, The University of Tokyo
"Search for Cancer Chemotherapeutics from Japanese Marine Invertebrates" |
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:30 pm | D. John Faulkner, Scripps Institution of Oceanography
"Recent Studies of Western Pacific Marine Invertebrates" |
| 8:30 pm - 8:35 pm | Discussion |
| 8:35 pm - 8:55 pm | William Gerwick, Oregon State University
"New Structural Classes of Marine Cyanobacterial Cytotoxins and Antifungals" |
| 8:55 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Richard E. Moore, University of Hawaii
New Structures |
| 9:20 pm - 9:30 pm | Discussion |
| 9:30 pm -11:00 pm | Poster Session #3 continued |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30pm | MARINE BIOMATERIALS AND MARINE BIOINORGANIC CHEMISTRY |
| Discussion Leaders: Marcel Jaspers, University of Aberdeen, and Katherine Barbeau, Scripps Institution of Oceanography |
| 9:00 am - 9:40 am | Herbert Waite UC Santa Barbara
"Molecular Counterparts of Mechanical Gradients Mussel Byssal Threads: Design Paradigms for Materials Engineering?" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:10 am | Jon Wilker, Purdue University
"Marine Adhesives" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am - 10:50 am | Coffee Break |
| 10:50 am - 11:20 am | Hitoshi Michibata, Hiroshima University
"The Unusual Mechanism of Accumulation and Reduction of Vanadium by Ascidians" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Katherine Barbeau, Scripps Institution of Oceanography
"Photochemically Reactive Siderophores Produced by Marine Bacteria" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Jayme Carter
"Reactivity of Vanadium Bromoperoxidase: Enzyme Induced Cyclization Reactions" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #4 |
| 6:00 pm | Dinner |
| 7:30 pm - 8:30 pm | Business Meeting |
| 8:30 pm - 9:30 pm | Award of THE PAUL J. SCHEUER AWARD IN MARINE NATURAL PRODUCTS CHEMISTRY |
| Discussion Leader: Tatsuo Higa, University of the Ryükyus |
| 8:30 pm | Isao Kitagawa, Osaka University |
| 9:30 pm -11:00 pm | Poster Session #4 continued |
