Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Genetically Encoded Small Molecules from Marine
Organisms |
| Discussion Leader: Shigeki Matsunaga (The University of Tokyo, Japan) |
7:40 pm - 8:00 pm | Opening Remarks: Introduction by the GRC
Chairs and a Brief Recap of the GRS by the GRS Chairs |
8:00 pm - 8:40 pm | Bradley Moore (Scripps Institution of Oceanography, USA) "Biosynthetic
Gene Clusters - Nature's Gift to Discovery and Application" |
8:40 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Tal Luzzatto-Knaan (University of California, San Diego, USA) "Chemodiversity Based Cartography of Natural Products from Marine Communities" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Synthetic Biology of Natural Products |
| Discussion Leader: Mohamed Donia (Princeton University, USA) |
9:00 am - 9:30 am | Emily Balskus (Harvard University, USA) "Chemical Discovery in the Microbial World" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Eric Schmidt (University of Utah, USA) "Novel Neuroactive Marine Natural Products" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Jason Kwan (University of Wisconsin-Madison, USA) "Using Shotgun Metagenomics to Investigate Natural Products from Uncultured Bacteria in Marine Invertebrates" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: Xinyu Liu (University of Pittsburgh, USA) "An Emerging View of Hapalindole-Type Alkaloid Biogenesis" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Sarah O'Connor (John Innes Centre, United Kingdom) "Understanding How Nature Makes Nitrogen-Containing Natural Products: Elucidating and Engineering Alkaloid Pathways from Plants" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
3:00 pm - 4:00 pm | Power Hour |
| The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring. |
| Organizer: Lena Gerwick (University of California, San Diego, USA) |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Molecular Targets and Omics Approaches |
| Discussion Leader: Roberto Berlinck (University of Sao Paulo, Brazil) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:20 pm | Leticia Costa-Lotufo (University of Sao Paulo, Brazil) "Prospecting Anticancer Compounds on the Brazilian Coast: From Simple to Complex and Back" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Carole Bewley (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA) "Anti-Infectives from Nature: Identifying Targets and Elucidating Mechanisms" |
9:15 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Organismal Interactions in Wet and Not-so-Wet Worlds |
| Discussion Leader: Amy Lane (University of North Florida, USA) |
9:00 am - 9:30 am | Toshiyuki Wakimoto (Hokkaido University, Japan) "Activated Chemical Defense of a Sponge-Microbe Association" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Danielle Dixson (University of Delaware, USA) "The Importance of Including Chemically Mediated Behavior in Creating Effective Marine Management" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Jessie Ochoa (University of California, Santa Cruz, USA) "Phylogenetic and Metabolomic Analysis Contributes to Emerging Spirotetronate Polyketides" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: Kristen Whalen (Woods Hole Oceanographic Institution, USA) "Louder than Words: Bacterial Cell Signals Are Drivers of Algal Lysis" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Martin Kaltenpoth (Johannes Gutenberg University of Mainz, Germany) "Evolution and Chemical Ecology of Defensive Microbial Symbioses in Insects" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Antibiotic Discovery and Microbial Secondary Metabolism |
| Discussion Leader: Brian Murphy (University of Illinois at Chicago, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:20 pm | Mohammad Seyedsayamdost (Princeton University, USA) "Unveiling the Hidden Secondary Metabolomes of Bacteria" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Stefan Schulz (Technische Universität Braunschweig, Germany) "Volatiles from Marine Bacteria" |
9:15 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Creative Chemical Solutions to Mysterious Molecules |
| Discussion Leader: Tim Bugni (University of Wisconsin-Madison, USA) |
9:00 am - 9:30 am | Tadeusz Molinski (University of California, San Diego, USA) "Integrated Approaches for Discovery of Bioactive Natural Products from Marine Invertebrates" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Richmond Sarpong (University of California, Berkeley, USA) "New Strategies and Methods for the Synthesis of Marine Alkaloids" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Thomas Williamson (Merck & Co. Inc., USA) "Small Molecule Structure Characterization: New and Improved NMR Methods" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: Danmeng Luo (University of Florida, USA) "Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lynbyastatin 7 and In Vitro Biological Evaluation in Model Systems for Pulmonary Diseases" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Kirk Gustafson (National Cancer Institute, NIH, USA) "Interesting New Structures and How We Can Solve Them: Application of Contemporary Structural Elucidation Techniques" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Microbial Signaling in a Vast Ocean |
| Discussion Leader: David Rowley (University of Rhode Island, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:20 pm | Tracy Mincer (Woods Hole Oceanographic Institution, USA) "Listening in on Microbial Natural Product Production Under Perturbation: Towards Understanding Global Cellular Production of Secondary Metabolites" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Georg Pohnert (Friedrich-Schiller-Universität Jena, Germany) "Gradients and Events: The Chemistry of Plankton Interactions" |
9:15 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Targeting Human Disease with Natural Products |
| Discussion Leader: Yali Fu (National Cancer Institute, NIH, USA) |
9:00 am - 9:30 am | Anokha Ratnayake (Pfizer, USA) "The Process of Designing and Developing Natural Products-Based Antibody Drug Conjugates for the Treatment of Cancer" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Robert Capon (University of Queensland, Australia) "Exploring Microbial Chemical Ecology as a Pathway for Accessing Silent Secondary Metabolism" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Samantha Mascuch (Georgia Institute of Technology, USA) "Mechanism of Action of the Cyanobacterial Marine Natural Product Honaucin A" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: James Anson (Royal Society of Chemistry, United Kingdom) "Marine Natural Products Review Article: A New Look for 2016" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | John MacMillan (University of Texas Southwestern Medical Center, USA) "Microbial Natural Products with Selective Activity Against Non-Small Cell Lung Cancer" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session: Development of Marine Natural Products as
Pharmaceuticals and Tools for Research |
| Discussion Leader: Paul Jensen (Scripps Institution of Oceanography, USA) |
7:30 pm - 7:45 pm | Opening Remarks |
7:45 pm - 8:15 pm | Eduardo Esquenazi (Sirenas Marine Discovery, USA) "A Small Company's Perspective on Opportunities
for Marine Inspired Drug Discovery and Development in Today's Pharma Environment" |
8:15 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Ronald Quinn (Griffith University, Australia) "Towards the Bedside: The Journey from 10 kg
Marine Organism and Animal Screening to Molecular Targets to Patient-Derived
Cells" |
9:10 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |