Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Bioactive Peptides from Philippine Marine Organisms
Dr. Lilibeth Salvador heads the Marine Pharmacognosy Lab at the Marine Science Institute at the University of the Philippines, Diliman. After completing her doctorate in Pharmaceutical Sciences - Medicinal Chemistry at the University of Florida under the mentorship of Dr. Hendrik Luesch, she returned to UP Diliman to advance the marine natural products research capacities of the Philippines.
Discussion Leader: Jonathan Singh (Victoria University of Wellington, New Zealand)
3:45 pm - 4:15 pm
Lilibeth Salvador (University of the Philippines, Philippines)
"Bioactive Peptides from Philippine Marine Organisms"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Exploring Structural Diversity: Enzymatic and Synthetic Routes to Complex Metabolites
Discussion Leader: David Gallegos (University of Utah, USA)
7:30 pm - 7:50 pm
David Brumley (University of Florida, USA)
"Discovery, Total Synthesis and Bioactivity of Novel Halogenated Depsipeptides"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Silja Mordhorst (ETH Zürich, Switzerland)
"The Remarkable Substrate Promiscuity of OspR: A New Ornithine-Generating Maturase Involved in the Biosynthesis of the Cryptic Antiviral Proteusin Natural Product Landornamide A"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Bhuwan Chhetri (Georgia Institute of Technology, USA)
"Absolute Configuration Determination of Complex Natural Products Using Glycosides as Internal Probes via Quantitative NOE-Based NMR Spectroscopy"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Eric Helfrich (Harvard Medical School, USA)
"Designing Modular Chassis for the Efficient Production of Complex Bacterial Sesqui- and Diterpenoids"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Serina Robinson (BioTechnology Institute, University of Minnesota, USA)
"Genome Mining-Guided Insights into Beta-Lactone Natural Product Biosynthesis"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cross-Talk: Chemical Interactions in Natural Systems
Discussion Leader: Kelsey Alexander (University of California, San Diego, USA)
9:00 am - 9:20 am
Stephanie Heard (University of Utah, USA)
"Elucidating the Biosynthesis of Penilumamide from a Marine Fungal Endophyte and Exploring the Ecological Role of Its Lumazine Building Block"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Paige Mandelare-Ruiz (University of Florida, USA)
"Allianthrones A and D: Selective Cytotoxic Bianthrones from Marine Aspergillus alliaceus "
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
David Delgadillo (University of California, Santa Cruz, USA)
"Chemical and Biological Investigation of Ikarugamycin"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Riley Kirk (University of Rhode Island, USA)
"A Multi-Year Investigation into the Pseudo-Nitzschia Community Occupying Narragansett Bay, Rhode Island with Emphasis on Environmental Drivers of Domoic Acid Production"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Kevin Jace Miranda (University of Aberdeen, United Kingdom)
"Genome-Mining Guided Isolation of a New Class II Lasso Peptide from Extremotolerant Deep-Sea Pseudomonas sp. SST3 Leading to New Biosynthetic Route for Lasso Peptide Production"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Enabling Technologies: Platform Systems for Natural Product Discovery
Discussion Leader: Michael Mullowney (Northwestern University, USA)
1:30 pm - 1:45 pm
Chase Clark (University of Illinois at Chicago, USA)
"IDBac: Bioinformatics Software for Microbial Drug Discovery Prioritization and Culturomics Characterization"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Sylvia Kunakom (University of Illinois at Chicago, USA)
"Development of a Bacterial Host for Natural Product Discovery and Production"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Sanghoon Lee (Simon Fraser University, Canada)
"NP Analyst: An Open Online Platform for Compound Activity Mapping"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
