SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:20 pm - 7:30 pm | Chairs' Introduction: Kevin Staley and Ivan Soltesz |
7:30 pm - 9:30 pm | New approaches to the pathophysiology and therapy of epilepsy |
7:30 pm - 8:20 pm | Ray Dingledine (Emory)
Gene expression profiling in epilepsy |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 9:20 pm | Richard Miles (Paris)
Epileptiform activities in human and animal hippocampus: a personal view |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Epileptogenic ion channels |
| Discussion Leader: Heinz Beck (Bonn) |
9:00 am - 9:25 am | Heinz Beck (Bonn)
Seizure-induced alterations in ion channels |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Jeff Noebels (Baylor)
Large Scale Profiling of Ion Channel Gene Variants in Epilepsy |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:05 am | Miriam Meisler (University of Michigan)
Epileptogenic sodium channel mutations |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Cha-Min Tang (Baltimore)
Dendritic and axonal potassium channels and epilepsy |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Christophe Bernard (France)
Acquired K-channelopathies |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Group Photo / Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Epileptogenic dysgenesis (In memoriam: Larry S. Bernardo) |
| Discussion Leader: David Prince (Stanford) |
7:30 pm - 7:50 pm | David Prince (Stanford)
Epileptogenesis after neocortical injury: Do faulty interneurons play a role? |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Scott Baraban (UCSF)
Malformations in the hippocampus |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Philip Haydon (University of Pennsylvania)
Physiological and Pathological Roles Glutamate-mediated Gliotransmission |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Helen Scharfman (Columbia)
Hilar circuit changes during epileptogenesis |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Homeostatic plasticity and epilepsy |
| Discussion Leader: Terry Sejnowski (Salk) |
9:00 am - 9:25 am | Terry Sejnowski (Salk)
Homeostatic mechanisms of network synchronization |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Astrid Prinz (Emory)
Similar network activity from disparate circuit parameters |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:05 am | Istvan Mody (UCLA)
Blocking Inhibition to Block Seizures: Insights into the Mechanisms of ADNFLE |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | David McCormick (Yale)
Mechanisms of adaptation in cortical neurons |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | John Swann (Baylor)
Homeostasis and hippocampal hyperexcitability |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Structural reorganization in epilepsy |
| Discussion leader: Yehezkel Ben-Ari (INSERM U 29) |
7:30 pm - 7:50 pm | Yehezkel Ben-Ari (INSERM U 29)
Plasticity of GABAergic signaling in epileptogenesis |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Jaideep Kapur (U Virginia)
GABA receptors and epilepsy |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Tamas Freund (Budapest)
Microcircuit alterations in the human epileptic brain |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Arnold Kriegstein (UCSF)
Stem cells and epilepsy |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Hypersynchrony and non-linear dynamics |
| Discussion Leader: John Huguenard (Stanford) |
9:00 am - 9:25 am | John Huguenard (Stanford)
Modulation of thalamocortical synchrony |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Steve Schiff (Krasnow Institute)
Seizures as Imbalanced States: Interneurons, Irises, Spirals, and Stages |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:05 am | Wim van Drongelen (Chicago)
Emergence of epileptiform activity |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Brian Litt (U. Penn)
Non-linear analysis of EEG data and seizure prediction |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | John White (Boston U)
Synchronization in hybrid neuronal networks |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 2 |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Gap junctions in epilepsy |
| Discussion leader: Barry Connors (Brown) |
7:30 pm - 7:50 pm | Barry Connors (Brown)
Activity-dependent regulation of gap junctions |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Gabor Tamas (Szeged, Hungary)
The impact of single neurons on microcircuit dynamics in the human cerebral cortex |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Hanna Monyer (Heidelberg, Germany)
Molecular biology of gap junctions |
8:50 pm - 9:00 pm | Discussion |
9:10 pm - 9:20 pm | Roger Traub (SUNY Brooklyn)
Role of gap junctions in synchronization |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Key events underlying epileptogenesis |
| Discussion Leader: Jim McNamara (Duke) |
9:00 am - 9:25 am | Jim McNamara (Duke)
BDNF in epileptogenesis |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Carolyn Houser (UCLA)
Plasticity of the delta subunit of the GABA-A receptor in epilepsy |
10:00 am - 10:10 am | Discussion |
10:10 am | Coffee Break |
10:40 am - 11:05 am | Amy Brooks-Kayal (U Penn)
Long-term effects of anti-convulsants on the developing brain |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Frances Jensen (Harvard)
Interplay of neurotransmitter systems in developmental seizures |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Greg Holmes (Dartmouth)
Early seizures, later behavior, and epileptogenecity |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 2 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Entorhino-hippocampal interplay in epilepsy (In memoriam: Angel Alonso) |
| Discussion Leader: Ed Dudek (Salt Lake) |
7:30 pm - 7:50 pm | Ed Dudek (Salt Lake)
Monitoring epileptogenesis |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Viji Santhakumar (UCLA)
Altered network topology in temporal lobe epilepsy |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Nelson Spruston (Northwestern)
Output-mode transitions in the subiculum |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Paul Buckmaster (Stanford)
Entorhinal-hippocampal activity before spontaneous seizures |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |