Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Approaching Complexity in Neuroscience and Epilepsy
Discussion Leader: Laura Ewell (University of California - Irvine, United States)
3:15 pm - 3:45 pm
Heinz Beck (University of Bonn Medical Center, Germany)
"Approaching Complexity in Neuroscience and Epilepsy"
3:45 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Molecular and Network Complexity in Epilepsy
Multiple attendees will be invited to give short talks based on their submitted abstracts
Discussion Leader: Chris Dulla (Tufts University School of Medicine, United States)
5:30 pm - 5:50 pm
Introduction by Discussion Leader
5:50 pm - 6:05 pm
Zoe Christenson Wick (Icahn School of Medicine at Mount Sinai, United States)
"Closed-Loop Control of Inhibitory Theta Phase Locking and its Impact on Seizures and Cognition"
6:05 pm - 6:15 pm
Discussion
6:15 pm - 6:30 pm
Barna Dudok (Stanford University School of Medicine, United States)
"Dichotomy of Basket Cell Recruitment During Seizures"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 6:55 pm
Zin-Juan Klaft (Tufts University - Department of Neuroscience, United States)
"Transiently Expressed GluN2D-containing NMDA-Rs Regulate Excitation of Interneurons During Cortical Development"
6:55 pm - 7:05 pm
Discussion
7:05 pm - 7:20 pm
Anthony Umpierre (Mayo Clinic, United States)
"Microglial Calcium Signaling in Epileptogenesis"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Therapeutic Mechanisms in Epilepsy
Multiple attendees will be invited to give short talks based on their submitted abstracts
Discussion Leader: Jeffrey Noebels (Baylor College of Medicine, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:35 am
Christos Lisgaras (New York University, United States)
"Hippocampal Area CA2 as a Novel Therapeutic Target in Epilepsy"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Laura Bell (University of Utah, United States)
"Reactive NG2-Glia Show Lasting Alterations in Their Response to Purinergic Damage Signals Following Viral Brain Infection and Seizures"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Marisol Sampedro Castañeda (The Francis Crick Institute, United Kingdom)
"Epilepsy-Linked Kinase CDKL5 Regulates Cav2.3 Kinetics and Modulates Neuronal Excitability"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Biswajit Maharathi (University of Illinois at Chicago, United States)
"Interictal Spike Propagation Networks Predict Seizure Onset Zones in Lesional and Non-Lesional Neocortical Epilepsy"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Florian Donneger (Sorbonne Université, Institut du Fer à Moulin, INSERM, France)
"Enhancing KCC2 Function Prevents Epileptiform Activity In Vitro and In Vivo "
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Development in Epilepsy Research
Small group mentoring session (<10 participants per group) with experts in funding, publishing, academic job search (faculty and postdoc), industry job search, and networking. There will be representation from various funding institutions to speak on funding and research in both the United States and Europe
Discussion Leader: Vicky Whittemore (National Institute of Neurological Disorders and Stroke, NIH, United States)
1:30 pm - 2:30 pm
Panel Discussion
Career Development in Epilepsy Research
Jennifer Brummet (American Epilepsy Society, United States)
Chris Dulla (Tufts University School of Medicine, United States)
Heinz Beck (University of Bonn Medical Center, Germany)
Jeffrey Noebels (Baylor College of Medicine, United States)
Laura Ewell (University of California - Irvine, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
