Reception: 5-6 PM Sunday, June 17
Morning sessions: 9.00 AM - 12.30 PM
Evening sessions: 7.15 PM - 9.45 PM
Sun PM | From the nucleus to the Golgi |
Welcome and introduction: Don Hilgemann (UTSW)
Nuclear pore 1 : Structure & function of the nuclear pore - the Ran story
Mary Moore (Baylor, Houston)
Nuclear Pore 2: Dynamic pore function and its regulation by phosphoinositides
Susan Wente (Washington University, St. Louis)
KEYNOTE LECTURE:
Regulation of protein translocation and membrane traffic in the
secretory pathway - Passing the driver's exam -
Randy Schekman (UC Berkley)
Mon AM | Trafficking & targeting |
Discussion leader: John York, Duke
Transporter trafficking in yeast: From ER to Golgi Chris Kaiser (MIT)
Traffic checkpoint for potassium channels Lily Jan (UCSF)
- break -
Sorting & trafficking of transporters & pumps Mike Caplan (Yale)
Lipid rafts and consitutive membrane transport Kai Simons (Max Planck,
Heidelberg/Dresden)
Mon PM | Regulated insertion & retrieval |
Discussion leader: Daniela Rotin, U Toronto
Control of GLUT4 glucose transporters through the actions of molecular motors
Mike Czech (U Mass, Wocester)
Regulation of insertion/retrieval by small G-proteins (TC10) Jeff Pessin (U Iowa)
- break -
Aquaporin 2 recycling: new signals for old pathways Dennis Brown (Harvard)
NEDD4: Ubiquitin-dependent retrieval Olivier Staub (U Lausanne)
Tues AM | New insights into pH regulators and their regulation |
Discussion leader: Orson Moe, UTSW, Dallas
Na/H exchange: the world's most regulated transporter meets PIP2
John Orlowski (McGill)
Functional and regulational roles of Calcineurin-Homologeous
Protein Shigeo Wakabayashi, Osaka
Beyond pHi homeostasis - new roles for the Na-H exchanger
in cytoskeletal organization and cell migration Diane Barber (UCSF)
- break -
NBCn1: A Na/bicarbonate cotransporter with associated sodium channel Walter Boron (Yale)
SPECIAL TALK:
Closing in on the structure of water channels: 3D structure of GlpF
Robert Stroud (UCSF)
Tues PM | Iron transport: Emerging transport systems of great medical import. |
Discussion leader: Jerry Kaplan, U. Utah, Salt Lake City
Regulation & pathology of metal ion transporters in the intestine
Matthias Hediger (Harvard)
Pathogen resistance & metal ion transporters (Nramp)
John Forbes (McGill, Montreal)
- break -
Regulation of iron homeostasis through the IRE/IRP system
Tracey Rouault (NIH, Bethesda)
New insights into metal ion transport in yeast
Valerie Culotta (Johns Hopkins, Baltimore)
Wed AM | Control & regulation of neurotransmitter transport. |
Discussion leader: Sela Mager, UNC, Chapel Hill
Control of glycine transport via transporters with different stoichiometries
Stephane Supplisson (Ecole Normale Superieure, Paris)
GTRAP-EAAT Interaction: G-protein regulation of glutamate transport.
Jeffrey D. Rothstein (Johns Hopkins, Baltimore)
- break -
Multiple operational modes of SERT Susan Amara (OHSU, Portland)
Keeping Up With Glutamate Release
Robert Edwards (UCSF)
Wed PM | The ABC's of transport. |
Discussion leader: Phil Thomas, UTSW, Dallas
ABC transporters: New roles in physiology and disease Chris Higgins (MRC, London)
The road to MDR inhibitors Michael Newman (Ontogen, Carlsbad)
<SURPRISE SHORT TALK>
- break -
Genomic approaches to study ABC transporters André Goffeau (Université catholique de Louvain, Louvain)
Cholesterol transport and its regulation by nuclear hormone receptors Helen Hobbs (UTSW, Dallas)
Thurs AM | New insights into regulation of epithelial transport. |
Discussion leader: Bliss Forbush, Yale
Regulation of Aquaporin-2 & its routing in health & disease
Peter Deen (Nijmegen, Netherlands)
Role of SGK in mineralocorticoid-regulated sodium transport
David Pearce (UCSF)
Fast-breaking short talk: Phospholipid and G Protein Modulation of
Epithelial Sodium Channels Doug Eaton (Emory)
- break -
Epithelial Cl channels in physiology & disease Thomas Jentsch (ZMNH,
Hamburg)
Epithelial sodium channel: mouse models mimicking human diseases
Bernard Rossier (U Laussane)
Thurs PM | Business Meeting (Don Hilgemann & Biff Forbush) |
Thurs PM | The past and future evolution of membrane transport |
Discussion leader: Carolyn Slayman, Yale
Genomic insights into the evolution of membrane transport
Milton H. Saier (UCSD)
A knockout for every gene and a chip for every purpose in studying
transport proteins in Arabidopsis
Michael R. Sussman (UW, Madison)
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