| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | The Amt/MEP/Rh Family and Gas Transport |
| Discussion Leader: Robert Stroud (UCSF) |
| 7:30 pm - 8:10 pm | Shahram Khademi (UCSF)
"Ammonia Transport by the Amt/MEP/Rh family" |
| 8:10 pm - 8:50 pm | Connie Westhoff (University of Pennsylvania)
"Mechanisms of the Rh proteins in the kidney, and in the red cell" |
| 8:50 pm - 9:30 pm | Walter Boron (Yale)
"The physiology of gas conducting channels in kidney and red cell" |
| 9:30 pm | Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Photo |
| 9:00 am - 11:15 am | Channels that are Transporters and Vice Versa |
| Discussion Leader: Robert Edwards (UCSF) |
| 9:00 am - 9:35 am | Tzyh-Chang Hwang (University of Missouri)
"Seeing the unseeable in CFTR gating" |
| 9:35 am - 10:10 am | Nico Reyes (Rockefeller University)
"Physical characteristics of ion pathway through Na,K-ATPase revealed by palytoxin" |
| 10:10 am | Coffee Break |
| 10:45 am - 12:30 pm | P-Type ATPases |
| Discussion Leader: Jack Kaplan (University of Illinois at Urbana-Champaign) |
| 10:45 am - 11:20 am | Jose Arguello (Worcester Polytechnic Institute)
"Heavy metal binding sites in P1B-ATPases" |
| 11:20 am - 11:55 am | Svetlana Lutsenko (Oregon Health & Science University)
"Function and Regulation of Human Copper-transporting ATPases, the Menkes disease and Wilson disease Proteins" |
| 11:55 am - 12:30 pm | Jack Kaplan (University of Illinois at Urbana-Champaign)
"Molecular and Cellular Aspects of hCTR1, the Human Cu(I) Transporter" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 8:00 pm | Channels - I. Mechanisms of Water Transport |
| Discussion Leader: Henning Stahlberg (UC Davis) |
| 7:30 pm - 8:00 pm | Bill Harries (UCSF)
"AQP0 Water Channels in the eye; mechanism of conduction" |
| 8:00 pm - 9:30 pm | Channels - II. Ion Channels |
| Discussion Leader: Volker Doetsch (U. Frankfurt) |
| 8:00 pm - 8:30 pm | Senyon Choe (Salk Institute)
"K channel structures" |
| 8:30 pm - 9:00 pm | Bernd Fakler (U. Freiburg)
"Proteomics of voltage-gated Kv1 potassium channels and channel gating by membrane lipids" |
| 9:00 pm - 9:30 pm | Cecilia Canessa (Yale)
"On proton-sensitivity of ASIC1: mechanism and conservation in the vertebrate lineage" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:55 am | Principles of Membrane Protein Construction |
| Discussion Leader: Michael Wiener (University of Virginia) |
| 9:00 am - 9:35 am | Don Engelman (Yale)
"Membrane protein folding and evolution" |
| 9:35 am - 10:10 am | Stephen White (UC Irvine)
"Translocon-assisted folding of membrane proteins" |
| 10:10 am | Coffee Break |
| 10:45 am - 11:20 am | James Bowie (UCLA)
"Principles of membrane protein structure with applications to biology and disease" |
| 11:20 am - 11:55 am | Volker Doetsch (Univ of Frankfurt)
"NMR structure determination of membrane proteins using multidimensional spectroscopy; the promise and prospects" |
| 11:55 am - 12:30 pm | Mechanisms of Transporters |
| Discussion Leader: Henning Stahlberg (UC Davis) |
| 11:55 am - 12:30 pm | Shimon Schuldiner (Hebrew University of Jerusalem)
"A Glimpse into the Binding Domain of EmrE, the Smallest Multidrug Transporter" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Major Facilitators |
| Discussion Leader: Peter Maloney (Johns Hopkins University) |
| 7:30 pm - 8:10 pm | Manuel Palacin (Barcelona University)
"Heteromeric Amino acid Transporters: from pathology to structure" |
| 8:10 pm - 8:50 pm | Ron Kaback (UCLA)
"How does the lactose permease instruct in the mechanisms of the superfamily of transporters" |
| Regulation of Transporters |
| 8:50 pm - 9:30 pm | Biff Forbush (Yale)
"Regulation of cation-chloride co-transporters" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ABC Transporters |
| Discussion Leader: TBA |
| 9:00 am - 9:35 am | Amy Davidson (Baylor College of Medicine)
"Viewing conformational changes in an ABC transporter by EPR spectroscopy" |
| 9:35 am - 10:10 am | Nancy Andrews (Harvard Med.)
"Disorders of Iron Homeostasis" |
| 10:10 am | Coffee Break |
| 10:45 am - 11:20 am | Adriana Donovan (Harvard Med.)
"The iron exporter ferroportin is essential for iron homeostasis" |
| 11:20 am - 11:55 am | Paola Vergani (Rockefeller)
"CFTR Channel Opening by ATP-driven tight dimerization of its nucleotide-binding domains" |
| 11:55 am - 12:30 pm | Barry Rosen (Wayne State Univ. School of Medicine)
"An arsenic chaperone for the ArsAB As(III)-translocating ATPase" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Translocation of Proteins |
| Discussion Leader: Stephen White (UC Irvine) |
| 7:30 pm - 8:10 pm | Michael Wiener (University of Virginia)
"The TonB-Dependent Outer Membrane Cobalamin Transporter BtuB" |
| 8:10 pm - 8:50 pm | Susan Buchanan (National Institutes of Health)
"Colicin binding to bacterial outer membrane transporters" |
| 8:50 pm - 9:30 pm | Bert Van Den Berg (University of Massachusetts)
"Protein secretion and membrane protein integration mediated by the SecY channel" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Synaptic Transporters |
| Discussion Leader: Ronald Kaback (UCLA) |
| 9:00 am - 9:35 am | Olga Boudker (Columbia University)
"Structural insights into mechanism of glutamate transporters" |
| 9:35 am - 10:10 am | Baruch Kanner (Hebrew University of Jerusalem)
"Structure and Function of Sodium-Coupled Neurotransmitter Transporters" |
| 10:10 am | Coffee Break |
| 10:45 am - 11:20 am | Michael Kavanaugh (University of Montana)
"Roles of the neuronal glutamate transporter EAAT3 in hippocampal synaptic transmission and plasticity" |
| 11:20 am - 11:55 am | Sandy Bajjalieh (University of Washington)
"SV2: A transporter-like protein that modulates vesicle fusion" |
| 11:55 am - 12:30 pm | Robert Edwards (UCSF)
"Vesicular glutamate Transporters" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | The Chloride Channel, or Transporter and an H+/Na+ Antiporter |
| Discussion leader: TBA |
| 7:30 pm - 8:10 pm | Raimund Dutzler (University of Zurich)
"Ion binding properties of the ClC selectivity filter" |
| 8:10 pm - 8:50 pm | Alessio Accardi (Brandeis University)
"Active transport mediated by a bacterial homologue of the CLC chloride channels" |
| 8:50 pm - 9:30 pm | Etana Padan (Hebrew University of Jerusalem)
"Structure of NhaA Na+/H+ antiporter, an insight into mechanism of action and regulation by pH" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
