Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
New Methods to Study Old Problems – Advances in Technology
Discussion Leader: Edward Twomey (Columbia University, USA)
3:45 pm - 4:10 pm
Arthur Laganowsky (Texas A&M University, USA)
"Ion Mobility Mass Spectrometry of Intact Membrane Protein Complexes"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Wei Mi (Harvard Medical School, USA)
"CryoEM Structure of the Retrotranslocon in the ERAD Pathway"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Studying Mechanisms of Membrane Proteins
Discussion Leader: Vedrana Mikusevic (Goethe University Frankfurt, Germany)
7:30 pm - 7:45 pm
Stephan Rempel (University of Groningen, The Netherlands)
"A New Mechanism of Vitamin B12 Transport in Bacteria"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Hundeep Kaur (Goethe University Frankfurt, Germany)
"Enzymatic and Structural Basis of Coupled ATPase-Adenylate Kinase Activity in MsbA"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
Altin Sula (Birkbeck, University of London, United Kingdom)
"The Complete Structure of an Activated Open Voltage Gated Sodium Channel Reveals a Novel Gating Interaction Motif"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
Scott Jackson (ETH Zurich, Switzerland)
"Structure and Function of the Human Multidrug Transporter ABCG2"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
Shai Silberberg (National Institute of Neurological Disorders and Stroke, NIH, USA)
"Rigor and Transparency: The Path Taken and the Path Forward"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Mentorship Component: Career Panel / New Views on Membrane Protein Dynamics
Discussion Leaders: Belinda Faust (Structural Genomics Consortium, University of Oxford, United Kingdom) and Sophie Rugg (University of York, United Kingdom)
9:00 am - 10:00 am
Panel Discussion
Navigating Complex Career Choices in Science
Katharina Duerr (University of Oxford, United Kingdom)
Sarah Miller (National Cancer Institute, NIH / Kelly Services, USA)
Yan Qi (Morrison & Foerster LLP., USA)
10:00 am - 10:10 am
Christoph Bock (Goethe University Frankfurt, Germany)
"TMD0 of TAPL: Solution NMR with a Membrane Embedded Accessory Domain"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Reza Dastvan (Vanderbilt University, USA)
"Proton Sensors of the E. coli Multidrug Transporter EmrE"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Wenchang Zhou (National Heart, Lung and Blood Institute, NIH, USA)
"Is the C-Subunit Ring of the F1Fo ATP Synthase the Elusive Mitochondrial Permeability Transition Pore?"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Marina Diskowski (Goethe University Frankfurt, Germany)
"Helical Jackknives Control the Double-Pore K+ Uptake System KtrAB"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Interactions of Membrane Proteins with Lipids and Ligands
Discussion Leader: Kerstin Kanonenberg (Heinrich Heine University Duesseldorf, Germany)
1:30 pm - 1:40 pm
Shannon Mostyn (University of Sydney, Australia)
"Heads or Tails: Lipid Inhibitors of the Glycine Transporter, GlyT2"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Melissa Pinard (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA)
"Structural Insights into the TonB-Dependent Outer Membrane Transporter LutA of Hypervirulent Klebsiella pneumoniae "
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:10 pm
Aaron Bozzi (Harvard University, USA)
"Molecular Mechanism of a Bacterial Nramp-Family Transition Metal Transporter"
2:10 pm - 2:15 pm
Discussion
2:15 pm - 2:25 pm
Albert Guskov (University of Groningen, The Netherlands)
"The Structural Basis of Proton Driven Zinc Transport by ZntB"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
