Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Understanding the Outer Membrane to Discover Novel Antibiotics
Discussion Leader: Jan-Ulrik Dahl (Illinois State University, United States)
3:45 pm - 4:05 pm
Nick Pokorzynski (Yale School of Medicine, United States)
"Cytoplasmic Magnesium Dictates Transcription of Catabolite- Repressed Genes"
4:05 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Steven Rutherford (Genentech, United States)
"Understanding the Outer Membrane to Discover Novel Antibiotics"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Decoding Transcriptional Regulation: Binding Affinity, Pro-Pausing, and Genetic Circuits
Discussion Leader: Grace Brewer (National Institutes of Health, National Institute of Allergy and Infectious Diseases, United States)
7:30 pm - 8:00 pm
Ayushi Mishra (Indiana University, United States)
"SwrA Promotes Swarming Motility by Increasing the Binding Affinity of DegU in Bacillus Subtilis"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
Expery Omollo (University of Wisconsin – Madison, United States)
"Structural and Functional Basis of the Universal Transcription Factor NusG Pro-Pausing Activity in Mycobacterium Tuberculosis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
Rosalind Pan (Caltech, United States)
"Dissecting Endogeneous Genetic Circuits from First Principles"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Bridging Scales in Gene Expression: From Structure to Dynamic Transcriptional Responses
Discussion Leader: Daniel Plaza (University of Cambridge, United Kingdom)
9:00 am - 9:20 am
Hunter North (Michigan State University, United States)
"NtrC DNA-Binding Domain Mutations Suppress Caulobacter Cell Cycle Control Defects"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Nick Pokorzynski (Yale School of Medicine, United States)
"Cytoplasmic Magnesium Dictates Transcription of Catabolite-Repressed Genes"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Karl Herbine (Thomas Jefferson University, United States)
"Structural Basis for Substrate Binding and Selection by Human Mitochondrial RNA Polymerase"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Tom Röschinger (Caltech, United States)
"Identifying the regulatory architecture of promoters in E. coli using high throughput sequencing"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leader: Valwynne Faulkner (The Francis Crick Institute, United Kingdom)
1:30 pm - 2:30 pm
Panel Discussion
Career Prospects in Academia and the Biotech Industry
Steven Rutherford (Genentech, United States)
Tatiana Mishanina (University of California San Diego, United States)
Jan-Ulrik Dahl (Illinois State University, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes