Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Mutation Strategies to Discover Mammalian Meiosis and Fertility Genes
Discussion Leader: Paula Cohen (Cornell University, USA)
3:45 pm - 4:20 pm
Philip Jordan (Johns Hopkins University Bloomberg School of Public Health, USA)
"Mutation Strategies to Discover Mammalian Meiosis Genes"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Initiation and Regulation of the Meiotic Program
Discussion Leader: Bernard de Massy (Institute of Human Genetics, France)
7:30 pm - 7:45 pm
Hui Tian (The Jackson Laboratory, USA)
"EWSR1 Regulates PRDM9-Dependent Histone 3 Methylation and Links Recombination Hotspots with the Chromosomal Axis"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Baolu Shi (University of Pennsylvania, USA)
"Dual Functions of the ssDNA-Binding Protein RPA in Meiotic Recombination"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Diedre Reitz (University of Chicago, USA)
"A Gain-of-Function Dmc1 Allele Reveals Distinct Mechanisms of Stimulation by Accessory Factors Mei5-Sae3 and Rad51"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Jasvinder Ahuja (National Cancer Institute, NIH, USA)
"Divergent Mechanisms in Formation of Noncrossovers and Crossovers Revealed on Fine Structure Analysis of Meiotic Recombinants"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Shaun Peterson (Memorial Sloan Kettering Cancer Center, USA)
"MSH2-Deficient Meiosis in F1 Hybrid Mice Reveals Meiotic Recombination Mechanism"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Carolyn Milano (Cornell University, USA)
"Elucidating MutSĪ³ Function During Mouse Meiosis Through the Generation of Point Mutant Mice"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Architecture and Dynamics of Meiotic Structures
Discussion Leader: Scott Keeney (Memorial Sloan Kettering Cancer Center, USA)
9:00 am - 9:15 am
Haitong Hou (National Cancer Institute, NIH, USA)
"When, How and Why Do Telomeres Control Meiotic Centromere Assembly"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Luciana Previato de Almeida (Oklahoma Medical Research Foundation, USA)
"Mps2/Kash5 Connects the LINC Complex to Molecular Motors on the Cytoskeleton to Mediate Chromosome Movements in Budding Yeast and Mouse Meiosis"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Chandni Ravindan (Wesleyan University, USA)
"A Constitutive 2:2 Complex Between Gmc2 and Ecm11 Within the Yeast Synaptonemal Complex"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Cori Cahoon (University of Oregon, USA)
"Synaptonemal Complex Architecture Facilitates Chromosome-Specific Regulation of Recombination in Drosophila "
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Jason Sims (University of Vienna, Austria)
"Meiotic DNA Repair in the Nucleolus Employs a NHEJ Mechanism"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Weronika Borek (University of Edinburgh, United Kingdom)
"The Ctf19/CCAN Kinetochore Complex Is Essential for Kinetochore-Microtubule Attachment in Meiosis I"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Meiotic Errors and Checkpoint Signaling Mechanisms
Discussion Leader: Needhi Bhalla (University of California, Santa Cruz, USA)
1:30 pm - 1:40 pm
Zhouliang Yu (University of California, Berkeley, USA)
"The DNA Damage Response Regulates Chromosome Axis Assembly During C. elegans Meiosis"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Viji Subramanian (New York University, USA)
"Ends: A Means to Establishing Chromosome Size Bias"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:10 pm
Stephen Wellard (Johns Hopkins Bloomberg School of Public Health, USA)
"Regulation of Synaptonemal Complex Disassembly by Aurora Kinases During Mouse and Human Meiosis"
2:10 pm - 2:15 pm
Discussion
2:15 pm - 2:25 pm
Kostika Sofroni (University of Hamburg, Germany)
"Control of Meiotic Progression Through Cyclin-Dependent Kinase Complexes"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
