| SUNDAY |
| 7:30 - 9:30 PM | The XYZ of ABC transporters |
| Nancy Carrasco (Chairperson) - Welcoming remarks |
| Discussion Leader: Lydia Aguilar (Baylor) |
| Michael Dean (NIH)
The evolution of ABC transporters and their role in human disease |
| Robert Tampé (Frankfurt)
ABCs in cellular immunity and viral persistence |
| Lydia Aguilar (Baylor)
ATP sensitive K+ channels. |
| Bruno Stieger (Zürich)
Bile salt and organic anion transporters. |
| MONDAY |
| 9:00 AM - 12:30 PM | Regulation everywhere (but not the red tape kind) |
| Discussion Leader: Silvia Corvera (U. Mass) |
| Käthi Geering (Lausanne)
The role of FXYD proteins in tissue- and isozyme-specific regulation of Na+,K+-ATPase |
| Michael Caplan (Yale)
ATPase sorting in polarized epithelial cells. |
| Silvia Corvera (U. Mass)
Glucose transporters and diabetes. |
| Donald Hilgemann (UT Southwestern)
Lipid signaling and ion transport |
| 12:00 PM | Photo |
| 7:30 - 9:30 PM | Channel proteins: to open or not to open, that is the question |
| Discussion Leader: Diane Papazian (UCLA) |
| Diane Papazian (UCLA)
Molecular rearrangements underlying voltage-dependent activation in potassium channels |
| Eduardo Perozo (U. of Virginia)
Structural basis for activation of channel gating. |
| Francisco Bezanilla (UCLA)
Molecular rearrangements during voltage gating. |
| Bernard Rossier (U. of Laussane)
New insights in ENaC gating. |
| TUESDAY |
| 9:00 AM - 12:30 PM | What's in a structure? |
| Discussion Leader: Mario Amzel - (Hopkins) |
| Katjusa Brejc (Cytokinetics, Inc., San Francisco)
An acetylcholine binding protein reveals information on the binding site of nicotinic receptors |
| Bing K. Jap (UC Berkeley)
The three dimensional structure of aquaporin. |
| Akihito Yamaguchi (Osaka University)
Crystal structure of a bacterial multi-drug efflux transporter |
| Mario Amzel (Hopkins)
H+ transport coupled ATP synthesis |
| 7:30 - 9:30 PM | Transporters: the road from here to there (and back) |
| Discussion Leader: Ernest Wright (UCLA) |
| Amy Davidson (Houston)
Characterization of intermediates in the pathway of maltose transport. |
| Ian Forster (Zürich)
Structure-function relations of the renal Na+/Pi cotransporter. |
| Hannelore Daniel (Munich)
The peptide transporter superfamily. |
| Ernest Wright (UCLA)
SGLT1 the mediator of active glucose transport. |
| WEDNESDAY |
| 9:00 AM - 12:30 PM | Health and disease as a matter of transport I |
| Discussion Leader: Christine Bear (U. of Toronto) |
| Christine Bear (U. of Toronto)
The molecular basis for CFTR function and dysfunction as a chloride ion channel |
| Douglas Eaton (Emory)
Aldosterone regulation of Na transport |
| Matthias Hediger (Harvard)
Regulation of metal ion transporters in the intestine. |
| Bruno Gasnier (Paris)
Molecular characterization of lysosomal transporters. |
| 7:30 - 9:30 PM | Health and disease as a matter of transport II |
| Discussion leader: Kathleen Giacomini (UCSF) |
| George Sachs (UCLA)
The gastric H+/K+ ATPase and the H. pylori urea transporter |
| Kathleen Giacomini (UCSF)
Pharmacogenetics of Xenobiotic Transporters. |
| Michael Newman (Ontogen)
Multidrug resistance inhibitors. |
| Jesús González (Aurora Biosciences)
Discovery and characterization of CFTR modulators. |
| THURSDAY |
| 9:00 AM - 12:30 PM | Neurotransmitter and other transporters |
| Discussion Leader: Susan Amara (Volume Institute) |
| Susan Amara (Volume Institute)
Excitatory amino acid transporters |
| Jonathan Javitch (Columbia)
Dopamine transporters |
| Gary Rudnick (Yale)
Serotonin Transporter: Too much of a good thing? |
| Sriram Subramaniam (National Institute of Health)
Molecular Architecture of a Bacterial Oxalate Transporter |
| 7:30 - 9:30 PM | From bioenergetics to mechanism |
| Keynote Lecture: H. Ronald Kaback (UCLA)
"Life with the lac permease" |
