SUNDAY |
2:00 pm - 9:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 pm - 9:00 pm | Towards 2D/3D-Structure of Membrane Transport Proteins: Swiss Contributions |
| Discussion Leader: Andreas Engel (Bale) & Heini Murer (Zurich) |
7:30 pm - 8:00 pm | Raimund Dutzler (Zurich)
"The structural basis of ClC channel function" |
8:00 pm - 8:30 pm | Kaspar Locher (Zurich)
"Structural and Functional Studies of Bacterial ABC Transporters" |
8:30 pm - 9:00 pm | Fritz Winkler (Villigen)
"Ammonium transporters: do they really transport ammonium?" |
9:00 pm | Welcome reception |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Structure/Function Relationship in Membrane Transport Proteins |
| Discussion Leader: Ernest M. Wright (Los Angeles) and Ian Forster (Zurich) |
9:00 am - 9:30 am | Baruch Kanner (Jerusalem)
"Molecular Determinants of Substrate Binding and Gating in Sodium- and Potassium-coupled Glutamate Transporters" |
9:30 am - 10:00 am | Ulrik Gether (Copenhagen)
"The Dopamine Transporter: 'zinc' twice" |
10:00 am | Coffee Break / Conference Photo |
10:30 am - 11:00 am | Hannelore Daniel (Munich)
“Electrogenic Proton-dependent Amino Acid and Peptide Transporters” |
11:00 am - 11:30 am | Don Loo (UCLA)
“Conformational Changes in SGLT1 Using Local Motion Detectors” |
11:30 am - 12:00 pm | Gary Rudnick (Yale, New Haven)
“Mechanistic insights into serotonin transporter function and regulation” |
12:00 pm - 12:30 pm | Invited Discussants:
Ana M Pajor (UTMB, Galveston)
Leila Virkki (Zürich)
and others |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Recently Discovered Amino Acid Transporter Families |
| Discussion Leaders: François Verrey (Zurich) & Stefan Broer (Canberra) |
7:30 pm - 8:00 pm | Yoshikatsu Kanai (Tokyo)
"The Na+-independent System-L like Amino Acid Transporter Family" |
8:00 pm - 8:30 pm | François Verrey (Zurich)
"Novel Epithelial Amino Acid Transporters" |
8:30 pm - 9:00 pm | Stefan Broer (Canberra)
"Hartnup disorder is caused by mutations in the neutral amino acid transporter SLC6A19" |
9:00 pm - 9:30 pm | free communications |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Transporter Proteins as Components of Heteromultimeric Complexes |
| Discussion Leader: Michael Caplan (New Haven) and Jürg Biber (Zurich) |
9:00 am - 9:30 am | Lydia Aguilar-Bryan (Baylor College, Houston)
"Assembling an ion channel from a pore and a transporter" |
9:30 am - 10:00 am | Christine Bear (Toronto)
"Chloride Channel Interactions within Multimeric Complexes" |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Michael Caplan (New Haven)
"Trafficking of Ion Transport Proteins: New Partners and Potential Therapies" |
11:00 am - 11:30 am | Ed Weinman (Baltimore)
"NHERF-1 and the Regulation of NHE3 and the Trafficking of Npt2a" |
11:30 am - 12:00 pm | Jeffrey Rothstein (Baltimore)
"Pathways for glutamate transporter regulation" |
12:00 am - 12:30 pm | Invited discussants:
Nati Hernando (Zürich) |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Transporter Proteins in Intracellular Organelles |
| Discussion Leader: Gary Rudnick (New Haven) and Bruno Hagenbuch (Zurich) |
7:30 pm - 7:55 pm | Robert Edwards (Standford)
"Developmental Regulation of Vesicular Glutamate Transport" |
7:55 pm - 8:15 pm | Dinesh Yernool (New York)
"Structure of a Glutamate Transporter Homolog from Pyrococcus Horikoshii" |
8:15 pm - 8:40 pm | Robert Tampé (Frankfurt)
"ABCs of Immunology: The Transporter Associated with Antigen Processing" |
8:40 pm - 9:05 pm | Gerard Brandolin (Grenoble)
"The Mitochondrial ADP/ATP Carrier" |
9:05 pm - 9:30 pm | Nathan Nelson (Tel Aviv)
"Structure and Function of V-ATPase" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Regulation of Membrane Transport Proteins |
| Discussion Leader: Amira Klip (Toronto) and Roland Wenger (Zurich) |
9:00 am - 9:25 am | Randy Blakely (Vanderbilt, Nashville)
"Vesicular Trafficking and Activation of Neurotransmitter Transporters" |
9:25 am - 9:50 am | Orson Moe (Southwestern, Dallas)
"New Insights into Acute Regulation of Na+/H+ Exchange" |
9:50 am | Coffee Break |
10:20 am - 10:45 am | Biff Forbush (New Haven)
"Function and Regulation of Na-K-Cl cotransporter" |
10:45 am - 11:10 am | Amira Klip (Toronto)
"Regulation of Glucose Transporters" |
11:10 am - 11:35 am | Antonio Zorzano (Barcelona)
"Regulation of GLUT4 glucose transporter gene transcription in muscle" |
11:35 am - 12:00 pm | H. Moo Kwon (U. Maryland, Baltimore)
"Transcriptional Regulation of Organic Osmolyte Transporters: Story of TonEBP/NFAT5" |
12:00 pm - 12:25 pm | Aurelio Galli (Vanderbilt, Nashville)
"DAT trafficking: vigilant border patrol" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mutations/Polymorphisms of Membrane Transport Proteins |
| Discussion Leader: Manuel Palacin (Barcelona) and Bruno Stieger (Zurich) |
7:30 pm - 7:55 pm | Rene J.M. Bindels (UMC, Nijmegen)
"TRP Channels and Hypomagnesemia Syndromes" |
7:55 pm - 8:20 pm | Josep Chillarón (Barcelona)
"Structure/function of the Heteromeric Amino Acid Transporters. First Steps towards a Molecular Understanding of Cystine and Dibasic Aminoacidurias" |
8:20 pm - 8:45 pm | Shu-Ichi Ueno (Tokushima)
"Genetic Polymorphisms of Neurotransmitter Transporters in Mental Disorders" |
8:45 pm - 9:10 pm | Yuichi Sugiyama (Tokyo)
"Drug Transporter Polymorphisms and Pharmakokinetics" |
9:10 pm - 9:30 pm | Kristopher Kahle (New Haven)
"The sodium/iodide symporter (NIS): from the molecule to the patient" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Gene Modified Animals and Membrane Transport Proteins |
| Discussion Leader: Bernard Thorens (Lausanne) and Carsten Wagner (Zurich) |
9:00 am - 9:30 am | Daniel Markovich (Brisbane)
"Characterization of the NaSi-1-null mouse phenotypes" |
9:30 am - 10:00 am | Nancy Carrasco (New York)
"The sodium/iodide symporter (NIS): from the molecule to the patient" |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Andreas Stahl (Palo Alto)
"Molecular Physiology of Fatty Acid Transport Proteins" |
11:00 am - 11:30 am | Edith Hummler (Lausanne)
"Epithelial sodium channels and sodium homeostasis" |
11:30 am - 12:00 pm | Bernard Thorens (Lausanne)
"Glucose Ttransporter and Glucose Sensing" |
12:00 pm - 12:30 pm | Ken Philipson (Los Angeles)
“Sodium-Calcium Exchange: Absence Makes the Heart Grow Fonder” |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7.30 pm | Business Meeting |
7:30 pm - 9:30 pm | Paracellular Transport |
| Discussion Leader: James M. Anderson (Chapel Hill) and Jonathan A. Javitch (New York) |
7:30 pm - 8:00 pm | James M. Anderson (UNC at Chapel Hill)
"Selectivity of Paracellular Transport" |
8:00 pm - 8:30 pm | Mikio Furuse (Kyoto)
"Claudins and Paracellular Transport" |
8:30 pm - 9:30 pm | Closing Lecture: Thomas Jentsch (Hamburg)
"Pathologies due to Defects in Chloride and Potassium Transport" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |