| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | YOU AREN’T WHAT YOU EAT WITHOUT MEMBRANE TRANSPORT PROTEINS |
| Discussion Leader: Lydia Aguilar Bryan (Baylor College of Medicine) |
| 7:30 pm - 7:55 pm | Nancy Carrasco (Albert Einstein College of Medicine)
"NIS" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Bernard Thorens (University of Lausanne)
"Glucose homeostasis and transporters" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:05 pm | Manuel Palacín (University of Barcelona)
"Heteromeric Amino Acid Transporters: the structure of the ectodomain of the heavy chain 4F2" |
| 9:05 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:30 pm | Poster Talk: Wanyoike W. Kang'ethe (University of California, Riverside)
"Aedes aegypti NHE8 mediates electroneutral Na+/H+ exchange across Malpighian tubule apical membrane and catalyzes Na+ and K+ transport in reconstituted vesicles" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | REGULATION OF MEMBRANE TRANSPORT PROTEINS |
| Discussion Leader: Aurelio Galli (Vanderbilt University) |
| 9:00 am - 9:25 am | Cecilia Canessa (Yale University)
"Sgk1 regulation of ion channels and transporters" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | Ulrik Gether (University of Copenhagen)
"CaMKII regulation of dopamine transporter function" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:40 am | Coffee Break |
| 10:40 am - 11:05 am | Melanie Cobb (University of Texas Southwestern)
"WNK1 regulation of membrane transport proteins" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 pm | Dany S. Adams (Forsyth Center for Regenerative and Developmental Biology)
"Some critical roles of ion flux during development and regeneration" |
| 11:40 pm - 11:50 pm | Discussion |
| 11:50 pm - 12:30 pm | Poster Talks: |
| Richard J. Reimer (Stanford University)
"Sialin, a proton coupled sialic acid transporter defines a novel vesicular compartment" |
| Carol Asher (Weizmann Institute of Science)
"Regulation of ion transport by FXYD proteins" |
| Edmund Kunji (Medical Research Council, DHNU)
"Mitochondrial carriers have a common substrate binding site in the cytoplasmic state" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PRIMARY TRANSPORTERS - STRUCTURE AND MECHANISM |
| Discussion Leader: Robert Tampé (Biocenter, Goethe-University Frankfurt) |
| 7:30 pm - 7:55 pm | Peter Dimroth (Swiss Federal Institute of Technology in Zurich)
"ATPase structure and function" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Jue Chen (Purdue University)
"Structure and function of ABC transporters" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:05 pm | Heather Pinkett (California Institute of Technology)
"ABC transporter structure" |
| 9:05 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:30 pm | Poster Talk: Thomas L. Sorensen (Diamond Light Source)
"ATP binding modes in the calcium pump" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PRIMARY TRANSPORTERS - INVOLVEMENT IN DISEASE |
| Discussion Leader: Robert Tampé (Biocenter, Goethe-University Frankfurt) |
| 9:00 am - 9:25 am | Joseph Bryan (Baylor College of Medicine)
"Sulfonylurea receptors and K(ATP) channels" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | Jack Oram (University of Washington)
"ATP-binding cassette transporter A1 and cholesterol trafficking" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:40 am | Coffee Break |
| 10:40 am - 11:05 pm | Kazu Ueda (Kyoto University)
"ABC proteins in lipid homeostasis" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 am | Robert Tampé (Biocenter, Goethe-University Frankfurt)
"The Transport Machinery TAP in Cellular Immunity" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:30 pm | Poster Talks: |
| Erik Procko (Harvard University)
"Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter" |
| Peter Chiba (Medical University of Vienna)
"Drug recognition and transport by multispecific drug efflux transporters" |
| Shimon Schuldiner (Hebrew University)
"On parallel and antiparallel topology of EmrE, an homodimeric multidrug transporter" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SECONDARY TRANSPORTERS - STRUCTURE AND MECHANISM |
| Discussion Leader: Gary Rudnick (Yale University School of Medicine) |
| 7:30 pm - 7:55 pm | H. Ron Kaback (University of California Los Angeles)
"Lac permease" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Etana Padan (Hebrew University of Jerusalem)
"NhaA" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:05 pm | Eric Gouaux (Oregon Health & Science University)
"Neurotransmitter transporters" |
| 9:05 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:30 pm | Poster Talk: Satinder Singh (Oregon Health & Science University)
"Structural basis for noncompetitive inhibition of a neurotransmitter sodium symporter" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SECONDARY TRANSPORTERS - INVOLVEMENT IN DISEASE |
| Discussion Leader: Gary Rudnick (Yale University School of Medicine) |
| 9:00 am - 9:25 am | Randy D. Blakely (Vanderbilt University)
"Neurotransmitter transporters in disease (autism)" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | Kevin Staley (University of Colorado)
"NKCC1 transporter and its role in seizures" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:40 am | Coffee break |
| 10:40 am - 11:05 am | Gajja S. Salomons (Vrije Universiteit Amsterdam)
"Creatine transporter dysfunction and mental retardation" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 am | Elena Bagley (University of Sidney)
"GAT currents and opiate withdrawal" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:30 pm | Poster Talks: |
| Gonzalo E. Torres (University of Pittsburgh)
"Direct interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin3" |
| Noa Rosental (Hebrew University)
"Dual role of two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter" |
| Joanna R. Dodd (University of Auckland)
"Identification of mutations that convert the creatine transporter into a GABA transporter" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CHANNELS - STRUCTURE AND MECHANISM |
| Discussion Leaders: Arthur Karlin (Columbia University) and Alfred L. George, Jr. (Vanderbilt University) |
| 7:30 pm - 7:55 pm | Diane M. Papazian (University of California Los Angeles)
"Voltage-gated potassium channels" |
| 7:55 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:30 pm | Ehud Isaacoff (University of California Berkeley)
"In situ optical biochemistry" |
| 8:30 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:05 pm | Alessio Accardi (Brandeis University)
"Transporters in channels" |
| 9:05 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:30 pm | Poster Talk: Renae M. Ryan (NINDS/NIH)
"Is the chloride conductance of glutamate transporters evolutionarily conserved?" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 9:00 am - 12:30 pm | CHANNELS - INVOLVEMENT IN DISEASE |
| Discussion Leaders: Alfred L. George, Jr. (Vanderbilt University) and Arthur Karlin (Columbia University) |
| 9:00 am - 9:25 am | Alfred L. George, Jr. (Vanderbilt University)
"Channelopathies in epilepsy and migraine" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 10:00 am | Peter Mohler (Vanderbilt University)
"Ion channel targeting and cardiac arrhythmias" |
| 10:00 am - 10:10 am | Discussion |
| 10:10 am - 10:40 am | Coffee break |
| 10:40 am - 11:05 am | Ted R. Cummins (Indiana University)
"Sodium channels and peripheral neuropathy" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:40 am | Ming Zhou (Columbia University)
"Redox modulation of Kv channels" |
| 11:40 am - 11:50 am | Discussion |
| 11:50 am - 12:30 pm | Poster Talks: |
| Stephen L. Altieri (Yale University)
"Ligand binding in cyclic nucleotide gated (CNG) channels" |
| Stuart S. Licht (Massachusetts Institute of Technology)
"Control of stochastic fluctuations in ATP-sensitive potassium channel gating" |
| Transporters and Ion Channels: Opportunities to Discover New Tools through the Molecular Libraries Screening Centers Network (MLSCN) |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | KEYNOTE PRESENTATION |
| Discussion Leader: Jonathan A. Javitch (Columbia University) |
| 7:30 pm - 8:30 pm | Rod MacKinnon (Rockefeller University)
"Channel structure and function" |
| 8:30 pm - 9:00 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
