This Gordon Research Conference (GRC) on Membrane Transport Proteins has been a highly successful GRC that focuses on recent discoveries in a diverse group of ATPases, ion channels and transporters. The Conference places particular emphasis on developing connections, both scientific and collaborative, between investigators who do not normally interact and on bringing young investigators into the transport protein field. The 2008 Conference will be the 6th meeting of this group and will continue to stress the role of transport proteins in both their normal physiologic setting and their role(s) in a wide variety of disease states. The program is fully international, the 2008 meeting will feature 40 investigators (25 from the USA, 15 from Europe and Japan) covering a wide range of topics including: Glucose Transport in the Brain, TRP Channels in Health and Disease, Trafficking of Membrane Transporters, Multiple Drug Resistance and Anti-microbial, Anti-cancer and Anti-epileptic Compounds, Structure of Membrane Transporters, CNS Diseases of Membrane Transporters, Heavy Metal Ion Transport, Membrane Transport and Metabolic Sensing, and Biotechnology: Molecular Sensors. The international scope of this conference is emphasized by the decision at the last meeting to alternate every two years between venues in the US and Europe in an effort to make the conference financially accessible to more investigators, particularly graduate students and post doctoral fellows.