Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Molecular and Translational Biology of Membrane Transport Proteins
Discussion Leader: Xunan Wang (University of Toronto, Canada)
3:15 pm - 3:20 pm
Introduction by Discussion Leader
3:20 pm - 3:35 pm
Marina Wright Muelas (University of Liverpool, United Kingdom)
"Deorphanisation of the Solute Carriers SLC16A11 and SLC16A14 via Untargeted Metabolomics"
3:35 pm - 3:40 pm
Discussion
3:40 pm - 3:55 pm
Zachary Frangos (University of Sydney, Australia)
"A Conserved Cholesterol Binding Site Modulates Glycine Transporter Functionality and Pharmacology"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Molecular and Translational Biology of Membrane Transport Proteins cont.
Discussion Leader: Samuel Mabry (University of Alabama at Birmingham, United States)
5:30 pm - 5:55 pm
Nancy Carrasco (Vanderbilt University, United States)
"The Tale of the Sodium/Iodide Symporter (NIS): From Its Cloning to Its Structure"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:15 pm
Balint Dudas (Université Paris Cité, France)
"ABCG2 Transport Mechanism Revealed through Kinetically Excited Targeted Molecular Dynamics Simulations"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:35 pm
Daniele Zanella (University of Alabama at Birmingham, United States)
"Bariatric Surgery and Bile Acids Modulate Central Cocaine Reward"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 6:55 pm
Marco Niello (Medical University of Vienna, Austria)
"New Psychoactive Substances to Investigate New Avenues of Transporter Pharmacology"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:25 pm
Michael Grabe (University of California, San Francisco, United States)
"Heating Things Up: A Mitochondrial Transporter that Thinks It's a Channel"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Structure and Function of Membrane Transport Proteins
Discussion Leaders: Carlos Cruz Cortes (University of Michigan, United States)
9:00 am - 9:15 am
Joana Fort (IRB Barcelona, Spain)
"LAT Transporters, from Function to Structure and Back"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
David Tippett (University of Zurich, Switzerland)
"Structural & Functional Characterisation of the SLC26A6 Anion Transporter"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Alexandra Schwartz (Vanderbilt University, United States)
"Conformational Dynamics of a Neurotransmitter:Sodium Symporter Homolog"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Jaroslava Seflova (Department of Cell and Molecular Physiology, Loyola University Chicago, United States)
"Sodium Pump Regulation in Health and Disease"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Svein Isungset Støve (University of Bergen, Norway, Norway)
"High-throughput Screening for VMAT2 Activity Modulators"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Erin Williams (University of Toronto, Canada)
"Characterizing the Binding of Bupropion and Ibogaine to the Human Dopamine Transporter"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Mentorship Stories from Membrane Transport Scientists
Discussion Leader: Ednah Ooko (Kenya Medical Research Institute (KEMRI) - Wellcome Trust, Kenya)
1:30 pm - 1:55 pm
Michael Grabe (University of California, San Francisco, United States)
"My Scientific Life Told in Transporters"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:25 pm
Nancy Carrasco (Vanderbilt University, United States)
"An Unending Source of Surprises"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes