Systems Biology and Integrative Omics for Precision Medicine

Metabolomics is the study of small molecules and the associated repertoire of biochemical reactions within cells, tissues, and biofluids of an organism. There is a need to understand metabolism at the large scale and complexity of systems biology to begin to impact human health and medicine. Integrative omics have emerged as quickly evolving technologies and have reinvigorated an interest in the study of the human metabolome, particularly as it pertains to health and disease. The key potential lies in the idea that the human metabolome provides a quantifiable and direct readout for health and disease states. In this respect, precision health reimagines these ideas from the viewpoint of the individual aiming to predict, prevent, and cure disease precisely. In this Gordon Research Seminar, we will focus on emerging systems biology technologies and their integration with metabolomics for the study of human health and disease. We will discuss and examine recent advancements in the field and their impact on disease mechanisms, heterogeneity, and progression and their impact on precision medicine. We will further cover critical challenges and future perspectives as well as the development of new tools and technologies. As is the goal and philosophy of GRS, we will highlight work from young scientists and emerging experts and nurture the emergence of a vibrant community that will enable future advancement in this exciting and quickly developing field. We invite early career members from academia, industry, and regulatory agencies to attend this meeting.