SUNDAY |
4:00 pm - 9:00 pm | Arrival and Check-in |
4:30 pm | Reception : Fellows' Garden |
7:30 pm - 9:30 pm | CHAIRS' SESSION |
| Discussion Leaders: Peter Caravan (EPIX Pharmaceuticals) and Peter J. Sadler (University of Edinburgh) |
7:30 pm - 7:45 pm | Welcome from Chairs and GRC |
7:45 pm - 8:30 pm | Bob Williams (University of Oxford)
"Natural Selection of the Elements for Medicine" |
8:45 pm - 9:30 pm | George McLendon (Duke University)
"Cytochrome c and the Suicide Hotline" |
9:45 pm | Chair's reception |
MONDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ANTIVIRALS AND ANTIMICROBIALS |
| Discussion Leader: Wiley Youngs (University of Akron) |
9:00 am - 9:20 am | Introductory comments, Discussion Leader. |
9:20 am - 9:50 am | Simon Silver (University of Illinois at Chicago)
"Silver as Biocides in Burn and Wound Dressings and Bacterial Resistance to Silver Compounds" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:15 am | Coffee Break |
10:15 am - 10:45 am | Carolyn L. Cannon (Washington University School of Medicine)
"Nebulized Silver Carbene Complexes for Treatment of Pulmonary Infections" |
10:45 am - 10:50 am | Discussion |
10:50 am - 11:20 am | Luigi Marzilli (Louisiana State University)
"Antiviral Activity of Platinum Complexes" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:55 am | Simon Fricker (Anormed)
"Metal Compounds for Treatment of Parasitic Diseases" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Round Table Discussion |
12:45 pm | Group Photo Followed by Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | METALS AND APOPTOSIS: THERAPEUTIC IMPLICATIONS |
| Discussion Leader: Larry Boise (University of Miami School of Medicine) |
7:30 pm - 7:45 pm | Introductory comments, Discussion Leader. |
7:45 pm - 8:15 pm | Milan Vasak (University of Zurich)
"Role of Metallothioneins in Health and Disease" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Colin Duckett (University of Michigan)
"Altered Properties of XIAP in Copper Toxicosis Diseases" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Valérie Lallemand (CNRS, Hôpital Saint Louis, Paris)
"PML, a specific target of As2O3 in Acute Promyelocytic Leukemia" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ANTICANCER COMPLEXES |
| Discussion Leader: Jan Reedijk (Leiden University) |
9:00 am - 9:20 am | Introductory comments, Discussion Leader. |
9:20 am - 9:50 am | Gianni Sava (University of Trieste)
"Ruthenium Complexes can Control Tumor Malignancy" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Eric Meggers (University of Pennsylvania)
"Protein Kinase Inhibition with Metal Complexes" |
10:25 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Coffee Break |
10:50 am - 11:20 am | Bernhard Keppler (University of Vienna)
"New Antitumor-Active Metal Complexes, Preclinical Development and Clinical Experience" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:55 am | Dolores Fregona (University of Padua)
"Metal Dithiocarbamate Complexes: A New Class of Potential Anticancer Drugs" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Round Table Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | METALS AND MAGNETIC RESONANCE IMAGING |
| Discussion Leader: Silvio Aime (University of Turin) |
7:30 pm - 7:45 pm | Introductory comments, Discussion Leader. |
7:45 pm - 8:15 pm | Tom Meade (Northwestern University)
"The Coordination Chemistry of q-modulated MR Contrast Agents" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Alan Koretsky (National Institutes of Health)
"Molecular and Cellular MRI of the Brain with Manganese and Iron" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Claire Corot (Guerbet)
"Superparamagnetic Iron Oxides Nanoparticles for Magnetic Resonance Imaging Applications" |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ANTI-DIABETIC METAL COMPLEXES |
| Discussion Leader: Chris Orvig (University of British Columbia) |
9:00 am - 9:20 am | Introductory comments, Discussion Leader. |
9:20 am - 9:50 am | Debbie C. Crans (Colorado State University)
"Investigating the Insulin-like Properties of Vanadium and Other Transition Metal Complexes" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Dieter Rehder (University of Hamburg)
"Targeting Insulin-enhancing Vanadium Complexes - Structure, Speciation and Action profile" |
10:25 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Coffee Break |
10:50 am - 11:20 am | Joan J. Guinovart (University of Barcelona)
"Anti-diabetic and Anti-obesity Properties of Tungstate" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:55 am | David L. Brautigan (University of Virginia)
"Chromium Complexes in Insulin Action" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Round Table Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | PHOTOTHERAPEUTIC AND PHOTODIAGNOSTIC AGENTS |
| Discussion Leader: Kazuko Matsumoto (Waseda university) |
7:30 pm - 7:45 pm | Introductory comments, Discussion Leader. |
7:45 pm - 8:15 pm | Jeffrey Zaleski (Indiana University)
"Radical Approaches to Photo-Therapeutics and Diagnostics: Rummaging Through the Metal-Ligand Toolbox" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | David Parker (University of Durham)
"Emissive Lanthanide Probes for Live Cell Imaging" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Stephane Petoud (University of Pittsburgh)
"Highly Sensitive and Photo-resistant Biosensors Based on Luminescent Lanthanide Complexes" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | RADIOPHARMACEUTICALS |
| Discussion Leader: Roger Alberto (Univ. of Zürich) |
9:00 am - 9:20 am | Introductory comments, Discussion Leader. |
9:20 am - 9:50 am | Clemens Decristoforo (Medical University Innsbruck)
"Targeting receptors with 99mTc labelled peptides: From Chemistry to Pharmacology to Imaging" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:25 am | Shuang Liu (Purdue University)
"Cationic 99mTc Radiotracers for Myocardial and Tumor Imaging" |
10:25 am - 10:30 am | Discussion |
10:30 am -10:50 am | Coffee Break |
10:50 am - 11:20 am | Jon Zubieta (Syracuse University)
"Bifunctional Chelates for Rhenium and Technetium and Their Applications to Nuclear Imaging" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:55 am | Hans-Juergen Wester (Technical University of Munich)
"Development and Evaluation of Tracers Labelled with [99mTc(CO)3(H2O)3]+" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Round Table Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | VICE-CHAIR'S SESSION |
| Discussion Leader: Sonya Franklin (University of Iowa) |
7:30 pm - 8:45 pm | Hot Topics picked by the Chairs and Vice-Chair |
8:45 pm - 9:15 pm | Hanns-Joachim Weinmann (Schering AG)
"Gadolinium Chelates for Diagnostic Imaging: From the Past to the Future" |
9:15 pm - 9:30 pm | Discussion |
FRIDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am | Depart |