SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | SPORULATION, CELL DIVISION AND THE CYTOSKELETON |
7:40 pm - 7:50 pm | Discussion Leader: Lotte SOGAARD-ANDERSEN (Max Planck Institute, Marburg) |
7:50 pm - 8:15 pm | Jeff ERRINGTON (Newcastle University) "Lives of ancient bacteria: Growth and division of bacteria lacking peptidoglycan" |
8:15 pm - 8:25 pm | Discussion |
8:25 pm - 8:50 pm | Richard LOSICK (Harvard Medical School)
"A Feeding Tube that Activates a Cell-Specific Transcription Factor" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | David RUDNER (Harvard Medical School) "Cell-cell signaling though regulated proteolysis: access to the caged interior of a membrane protease" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm | Reception |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | TOXINS, SECRETION SYSTEMS AND VIRULENCE FACTORS |
9:00 am - 9:10 am | Discussion Leader: Guy CORNELIS (Biozentrum Basel) |
9:10 am - 9:35 am | Samuel MILLER (University of Washington) "Recent structural progress on the rings that make up the Salmonella typhimurium type III secretion needle complex" |
9:35 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Aimee SHEN (Stanford University)
"Small molecule-induced allosteric activation of autoprocessing bacterial toxins" |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break / Group Photo (10:15 am) |
10:30 am - 10:55 am | John MEKALANOS (Harvard Medical School) "Cholera as a paradigm for understanding emergence, virulence and temporal
patterns of disease" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Wim HOL (University of Washington, Seattle) "Towards understanding the architecture of the Type 2 Secretion System" |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Wilbert BITTER (VU Amsterdam)
"Characterization of ESX-5, one of the mycobacterial type VII secretion systems" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Erec STEBBINS (The Rockefeller University)
"Mechanism of host kinase inhibition by H. pylori CagA" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | THE BACTERIAL CELL ENVELOPE |
7:30 pm - 7:40 pm | Discussion Leader: Jan TOMMASSEN (Utrecht University) |
7:40 pm - 8:05 pm | Guido GRANDI (Novartis, Siena) "Characterization of bacterial surface proteins and their interactions" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Chris WHITFIELD (University of Guelph) "Biosynthesis and assembly of microbial polysaccharides" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Gabriel WAKSMAN (Birkbeck College) "Molecular assembly machines at the outer membrane" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CELL-CELL COMMUNICATION AND REGULATORY NETWORKS |
9:00 am - 9:10 am | Discussion Leader: Stephen LORY (Harvard Medical School) |
9:10 am - 9:35 am | Stephen LORY (Harvard Medical School) "Complexity of regulatory networks controlling the expression of acute and chronic virulence factors in Pseudomonas aeruginosa" |
9:35 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Christophe GRANGEASSE (IBCP-CNRS, Lyon)
"Structural and functional insights into bacterial tyrosine-kinases" |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Hannah ENGELBERG-KULKA (Hebrew University) "The Toxin-Antitoxin module mazEF as a determinant of death, life, signaling and the multicellularity of bacteria" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Matthew PARSEK (University of Washington) "CdrA, a biofilm matrix cross-linking adhesin whose expression is controlled by cyclic-di-GMP" |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Jonathan DWORKIN (Columbia University) "Characterization of a novel signaling pathway that responds to peptidoglycan" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Sigal BEN-YEHUDA (Hebrew University)
"High error levels during bacterial gene expression-a source of robustness" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | BIOFILMS AND MICROBIAL COMMUNITY |
7:30 pm - 7:40 pm | Discussion Leader: Jean Marc GHIGO (Institut Pasteur) |
7:40 pm - 8:05 pm | George O’TOOLE (Dartmouth University) "To Build a Biofilm" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:25 pm | Lynn HANCOCK (Kansas State University)
"The role of fratricide in Enterococcus faecalis biofilm development" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:40 pm | Hera VLAMAKIS (Harvard Medical School)
"Extracellular signals dictate cell fate in biofilms" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:10 pm | Nathalie BALABAN (Hebrew University) "Noise in bacterial persistence" |
9:10 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | INFECTION AND IMMUNITY |
9:00 am - 9:10 am | Discussion Leader: Philippe SANSONETTI (Institut Pasteur) |
9:10 am - 9:35 am | Michael GILMORE (Schepens Eye Research Institute) "Modular structure and movement of the Enterococcus faecalis
pathogenicity island" |
9:35 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Benoît MARTEYN (Institut Pasteur/Imperial College London)
"Oxygen-dependent modulation of Shigella virulence" |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Fidel ZAVALA (Johns Hopkins University) "Development of memory CD8+ T-cell populations against malaria liver stages" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Alexis KALERGIS (Catholic University of Chile)
"Modulating the immunological synapse to enhance pathogen immunity" |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Sarkis MAZMANIAN (California Institute of Technology) "Say hello to your little friends; beneficial bacteria prevent inflammatory disease during commensalism" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Suzana SALCEDO (CIML/Marseille) "Subversion of innate immune responses by Brucella" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | MODELS TO STUDY HOST-PATHOGEN INTERACTIONS |
7:30 pm - 7:40 pm | Discussion Leader: Gad FRANKEL (Imperial College London) |
7:40 pm - 8:05 pm | Gordon DOUGAN (The Sanger Research Institute UK) "The infection lifecycle of C. difficile" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Dominique FERRANDON (CNRS, Strasbourg)
"Homeostasis of the Drosophila midgut epithelium during Serratia marcescens intestinal infections" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Raphael VALDIVIA (Duke University) "Heterologous expression systems for the identification and characterization of Chlamydia effector proteins" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
9:00 am - 12:30 pm | MODULATION OF HOST CELL RESPONSE BY PATHOGENS |
9:00 am - 9:10 am | Discussion Leader: Stephane MERESSE (CIML, Marseille) |
9:10 am - 9:35 am | Brad COOKSON (University of Washington) "Pyroptosis - host inflammatory response" |
9:35 am - 9:45 am | Discussion |
9:45 am - 9:55 am | Ana ARBELOA (Imperial College London)
"The WxxxE effector EspM2 is a RhoA guanine nucleotide exchange factor" |
9:55 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Michael WAY (Cancer Research UK, London)
"A common Nck and N-WASP dependent actin based motility in divergent vertebrate poxviruses" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Xavier NASSIF (INSERM Necker, Paris) "A tragic confusion at the blood brain interface is responsible for meningococcal meningitis" |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Richard FERRERO (Monash University) "NOD1 responses to H. pylori; An example in which host detection may
be synonomous with host subversion" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Leigh KNODLER (Rocky Mountain Laboratories, Montana) "Salmonella egress from polarized epithelia" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | INTRACELLULAR SURVIVAL |
7:30 pm - 7:40 pm | Discussion Leader: Joanne ENGEL (UCSF) |
7:40 pm - 8:05 pm | Christophe DEHIO (Biozentrum Basel) "Bartonella entry into endothelial cells and erythrocytes" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Craig ROY (Yale University) "Subversion of eukaryotic vesicle trafficking by Legionella pneumophila" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Kasturi HALDAR (Northwestern University)
"Pathogenic secretomes: from predictions to molecular function" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |