Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Signal Transduction Mechanisms Controlling Microbial Community Behavior |
| Discussion Leader: Matthew Parsek (University of Washington, USA) |
7:40 pm - 8:05 pm | Pete Greenberg (University of Washington, USA) "Quorum Sensing and Social Engineering in Bacterial Groups" |
8:05 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Kimberly Kline (Nanyang Technological University, Singapore) "Interspecies Biofilm Interactions Promote Polymicrobial Infection" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Allon Hochbaum (University of California, Irvine, USA) "The Role of Rhamnolipids in an Interspecies Biofilm Dispersal Signaling Pathway" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | John Whitney (University of Washington, USA) "Intoxication by a Type VI Secretion-Delivered NAD(P)+ Glycohydrolase Effector Requires a Target Cell Permissive Factor" |
9:25 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Surface Interactions and Their Impact on Cellular Physiology |
| Discussion Leader: Fitnat Yildiz (University of California, Santa Cruz, USA) |
9:00 am - 9:25 am | Jean-Marc Ghigo (Pasteur Institute, France) "Escherichi coli Adapts to Local Biofilm Conditions by Using a New Fermentation Pathway" |
9:25 am - 9:40 am | Discussion |
9:40 am - 9:50 am | Nathan Feirer (Indiana University Bloomington, USA) "Pterin-Dependent
Surface Attachment Control in Agrobacterium tumefaciens" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:05 am | Joe Harrison (University of Calgary, Canada) "A Bacterial Thermosensor Modulates Biofilm Formation in Response to Human Body Temperature" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Tracy Raivio (University of Alberta, Canada) "Surface Sensing by the CpxA Sensor Kinase" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:45 am | John Gunn (The Ohio State University, USA) "Mechanistic Insights into the Establishment and Maintenance of Salmonella Chronic Carriage" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Eric Klein (Rutgers University-Camden, USA) "Physiological Properties of the Caulobacter crescentus Stalk" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Medha Raina (National Institutes of Health, USA) "Investigation of a Highly-Regulated, 28-Residue Amphipathic Helix Protein AzuC" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Signaling Between the Host and Pathogen |
| Discussion Leader: Joerg Vogel (University of Wuerzburg, Germany) |
7:30 pm - 7:55 pm | Andreas Baumler (University of California, Davis, USA) "Why Is Getting Intimate So Important? Lessons Learned from AE Pathogens" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Jeffery Cox (University of California, San Francicso, USA) "Transporters at the Interface of Tb and the Host" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Craig Roy (Yale University School of Medicine, USA) "Autophagy Manipulation by Coxiella" |
9:15 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Bacterial Regulatory Networks |
| Discussion Leader: Joshua Woodward (University of Washington, USA) |
9:00 am - 9:25 am | Petra Dersch (Helmholtz Center for Infection Research, Germany) "Sensory and Regulatory RNAs as Mediators of Yersinia Virulence Gene Expression" |
9:25 am - 9:40 am | Discussion |
9:40 am - 9:50 am | Casey Greene (Geisel School of Medicine, Dartmouth College, USA) "Unsupervised Discovery of Genomic and Regulatory Features with ADAGE: Large-Scale Analysis of Gene Expression in the Bacterial Pathogen Pseudomonas aeruginosa" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:05 am | Linda Kenney (Mechanobiology Institute, Singapore) "A FRET Biosensor Tracks OmpR-Dependent Acidification of Salmonella in the Macrophage Vacuole" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Luciano Marraffini (The Rockefeller University, USA) "Co-Transcriptional DNA and RNA Cleavage During Type III CRISPR-Cas Immunity" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Aimee Shen (University of Vermont, USA) "Identification of a Novel Clostridium difficile Lipoprotein that Is Required for Spore Germination and Infection" |
11:30 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Julie Valastyan (Princeton University, USA) "Investigating Qrr4 Using RSort-Seq, a High-Throughput Strategy that Reveals Nucleotides Vital for sRNA Function in Bacteria" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Michelle Reniere (University of California, Berkeley, USA) "Virulence Gene Regulation of an Intracellular Pathogen" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Composition of the Interface |
| Discussion Leader: Nina Salama (Fred Hutchinson Cancer Research Center, USA) |
7:30 pm - 7:55 pm | Hank Steven Seifert (Northwestern University, USA) "How Are Some Pilus Functions Retained with Neisseria gonorrhoeae Pilus Variations?" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Samuel Miller (University of Washington, USA) "Cardiolipin Transport to the Outer Membrane Promotes Salmonella Virulence" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:00 pm | Swaine Chen (National University of Singapore / Genome Institute of Singapore, Singapore) "Complete Definition of Cis-Acting Mutations at the fimS Locus Regulating Type 1 Pili in E. coli by Saturating Genome Editing" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Antoine-Emmanuel Saliba (University of Wuerzburg, Germany) "Single-Cell RNA-Seq of Infected Macrophages Reveals the Host Response to Non-Replicating Salmonella" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | New Strategies for Antibiotics and Anti-Infectives |
| Discussion Leader: Kimberly Kline (Nanyang Technological University, Singapore) |
9:00 am - 9:25 am | Dirk Bumann (Biozentrum, University of Basel, Switzerland) "Salmonella Virulence and Control in Infected Tissues: Location, Location, Location" |
9:25 am - 9:40 am | Discussion |
9:40 am - 9:50 am | Ian Henderson (University of Birmingham, United Kingdom) "Resolution of Pseudomonas aeruginosa Infection in Patients Through Antibody Modulation" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:05 am | Edouard Jurkevitch (The Hebrew University of Jerusalem, Israel) "Prey Sensing and Its Effects on the Obligate Predatory Bacterium Bdellovibrio bacteriovorus Cell Cycle" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Jan-Willem Veening (University of Groningen, The Netherlands) "Antibiotic-Induced Bacteriocin Expression in the Human Pathogen Streptococcus pneumonia" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Elizabeth Libby (Columbia University, USA) "A Eukaryotic-Like Ser/Thr Kinase Mediates Induction of a (p)ppGpp Synthetase During Antibiotic Stress" |
11:30 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Jason Rosch (St Jude Children's Research Hospital, USA) "Novel Antibiotics for Gram-Positive Pathogens" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Nathalie Balaban (Hebrew University, Israel) "Experimental Evolution Under Intermittent Antibiotic Exposure" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | New Technologies and Genome-Wide Approaches |
| Discussion Leader: Christoph Dehio (Biozentrum, University of Basel, Switzerland) |
7:30 pm - 7:55 pm | Michael Gilmore (Harvard Medical School, USA) "Genome-Wide Comparisons Define the Genus Enterococcus and Its Colonization Properties" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Nassos Typas (European Molecular Biology Laboratory, Germany) "From High-Throughput Approaches to Molecular Mechanism" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Daniel Lopez (National Centre for Biotechnology (CNB), Spain) "Structural and Functional Characterization of Lipid Rafts in Staphylococcus aureus" |
9:15 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Bacterial and Eukaryotic Cell Biology |
| Discussion Leader: Karine Gibbs (Harvard University, USA) |
9:00 am - 9:25 am | Pascale Cossart (Pasteur Institute, France) "Cytoskeletal and Organelle Dynamics: New Concepts from Listeria Infections" |
9:25 am - 9:40 am | Discussion |
9:40 am - 9:50 am | Joel Selkrig (European Molecular Biology Laboratory, Germany) "Intracellular Salmonella enterica Typhimurium Modulates the Extracellular Proteome of Infected Cells" |
9:50 am - 9:55 am | Discussion |
9:55 am - 10:05 am | Renee Tsolis (University of California, Davis, USA) "The ER Stress-Induced Pro-Inflammatory Response Is Mediated by the NOD1/NOD2 Signaling Pathway" |
10:05 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | David Holden (Imperial College, United Kingdom) "Intracellular Anchoring of Salmonella Vacuoles" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Matthew Wargo (University of Vermont, USA) "Members of a Specific AraC Subfamily Mediate Detection of Host-Derived Accessory Nitrogen Compounds" |
11:30 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Joshua Woodward (University of Washington, USA) "Eavesdropping on Bacterial Conversations: A Novel Eukaryotic c-di-AMP-Binding Protein Affects Host Inflammation and Bacterial Pathogenesis" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Feng Shao (National Institute of Biological Sciences, China) "Innate Immune Sensing of Cytosolic Bacteria and Bacterial Virulence" |
12:15 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Model Systems for Studying Signal Transduction Networks |
| Discussion Leader: Daniel Lopez (National Centre for Biotechnology (CNB), Spain) |
7:30 pm - 7:55 pm | Fitnat Yildiz (University of California, Santa Cruz, USA) "Signal Transduction Networks Controlling Vibrio cholerae Biofilm Formation" |
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Karine Gibbs (Harvard University, USA) "Identity Information at the Nexus of Development and Defense in a Multicellular Community" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:00 pm | Salim Islam (CNRS - Laboratoire de Chimie Bactérienne, France) "Bacterial Gliding Motility Is Mediated by a Malaria-Like Cleavage of a Surface Adhesin" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Mauricio Pontes (Yale University, USA) "Cellular Translation Rates and c-di-GMP Signaling in Salmonella enterica" |
9:20 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |