Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: The Evolving Role of an Evolutionary Microbiologist
Discussion Leader: Eleanor Rand (Harvard University, United States)
3:45 pm - 4:15 pm
Bill Hanage (Harvard T.H. Chan School of Public Health, United States)
"Notes from a House on Fire: Lessons Learned from the SARS CoV 2 Pandemic"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Microbial Communities: Exploring the role of Phages, Bacteria, and their Environments
Discussion Leaders: Siân Owen (Harvard Medical School, United States) and Katherine Xue (Stanford University, United States)
7:30 pm - 7:40 pm
Anni Zhang (Massachusetts Institute of Technology, United States)
"CRISPR Spacer Acquisition is a Rare Event in Human gut Microbiome"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Amy Zamora (Harvard University, United States)
"Effects of Prophages on Evolutionary paths to Ciprofloxacin Resistance in S. Typhimurium"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Joshua Borin (University of California San Diego, United States)
"Bacteria-Phage Coevolution Rapidly Drives the Emergence of Multi-Scale Networks"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Jana S. Huisman (Massachusetts Institute of Technology, United States)
"The rate of Horizontal Gene Transfer in the gut"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Maribel Okiye (University of Michigan, United States)
"Unveiling the Biological Potential of the Human oral Microbiome"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Elisa Granato (University of Oxford, United Kingdom)
"Intermicrobial Warfare and Horizontal Gene Transfer"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Akshit Goyal (MIT, United States)
"Structured Interactions Explain the Absence of Keystone Species in Synthetic Marine Microcosms"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Mische Holland (University of Pittsburgh, United States)
"Uncovering Impacts of HGT and Recombination on Bacterial Virulence Genes"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Molecular Approaches to Microbial Ecology and Evolution
Discussion Leaders: Michael Blazanin (Yale University, United States) and J. Carlos R. Hernandez-Beltran (Max Planck Institute for Evolutionary Biology, Germany)
9:00 am - 9:10 am
Teresa Gil-Gil (CNB-CSIC, Spain)
"What’s the matter with MICs: The Contribution of Nutrients and Limiting Resources to the Pharmacodynamics of Antibiotics and Bacteria"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Tatiana Ruiz Bedoya (University of Toronto, Canada)
"The Emergence of Virulence via Collective Action of Bacterial Effectors"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Miaoxiao Wang (Department of Environmental Systems Science, ETH Zürich, Switzerland)
"Cell-cell Connection Mediated by Bacterial Stalks Facilitates Metabolic Cross-Feeding"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Evangeline Williams (Drexel University College of Medicine, United States)
"Shared and Divergent Transcriptional Responses During Haemophilus Influenzae Biofilm Formation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Mona Förster (University of Cologne, Germany)
"Distribution of Fitness Effects of Cross-Species Transformation Reveals Potential for Fast Adaptive Evolution"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Beatriz Baselga-Cervera (University of Minnesota, United States)
"Increased size and Morphological Diversity in the Cyanobacterium Anabaena Variabilis"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Rohan Maddamsetti (Duke University, United States)
"The Distribution of Duplicated Antibiotic Resistance Genes Across Complete Microbial Genomes Reflects Ecologically Relevant Selection and Horizontal Gene Transfer"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Xiaoyu Shan (Massachusetts Institute of Technology, United States)
"Mutation-Induced Infections of Phage-Plasmids"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
The Role of Microbial Evolution on Human Health
Discussion Leader: Kyle Card (Cleveland Clinic, United States)
1:30 pm - 1:40 pm
Alief Moulana (Harvard University, United States)
"Broad Protein Landscape Explorations of SARS-CoV-2 Omicron Lineages"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Elisa Visher (Stanford University, United States)
"Spatial Structure Reverses the Impact of local Adaptation on Pathogen Exploitation Rates"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:10 pm
Jorge Sastre-Dominguez (Spanish National Center for Biotechnology (CNB-CSIC) (CIF: Q2818002D), Spain)
"The Carbapenemase-Encoding Plasmid pOXA-48 Facilitates the Adaptation of Clinical Strains via Movement of Insertion Sequences"
2:10 pm - 2:15 pm
Discussion
2:15 pm - 2:25 pm
Davis Weaver (Case Western Reserve University, United States)
"Reinforcement Learning Informs Optimal Treatment Strategies to Limit Antibiotic Resistance"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes