SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair: Zachary Dalebroux (University of Washington) |
3:45 pm - 4:30 pm | Host-Pathogen Interactions |
| Discussion Leader: Aimee Richard (University of Pennsylvania) |
3:45 pm - 4:15 pm | Andrew Olive (Harvard Medical School)
"Chlamydia trachomatis-mediated alterations in host protein stability are required for bacterial growth" |
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I: Toxin Action and the Host Response to Infection |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mechanisms of Toxin Action |
| Discussion Leader: Francis Alonzo (NYU School of Medicine) |
7:30 pm - 7:50 pm | David Anderson (Medical College of Wisconsin)
"ExoU and Ubiquitin: A Model System for Bacterial-Host Protein Interaction and Effector Folding" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Ladislav Bumba (Institute of Microbiology - Czech Republic)
"Structural basis for RTX protein folding upon secretion through the Type I secretion system"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Andrew McCluskey (Harvard Medical School)
"Changing the receptor specificity of anthrax toxin" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Doris LaRock (University of Washington)
"A Salmonella Typhimurium translocated glycerophospholipid: cholesterol acyltransferase promotes virulence by binding to the RhoA switch regions" |
9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Immunity and the Host Response to Infection |
| Discussion Leader: Chris LaRock (University of Washington) |
9:00 am - 9:20 am | Dara Burdette (University of California-Berkeley)
"A Mechanism for the Innate Immune Sensing of Cyclic Dinucleotides" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Lisa Maudsdotter (Stockholm University-Sweden)
"Lactobacilli inhibit adherence of pathogenic bacteria to host cells by interfering with host cell calcium signaling" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Kerri-Lynn Sheahan (Tufts University)
"Host Cell Contribution to Type III Secretion in Yersinia pseudotuberculosis" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Sarah Clark (University of Pennsylvania)
"Phosphorylcholine allows for evasion of bactericidal antibody by Haemophilus influenzae" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II: Virulence Mechanisms of Bacterial Pathogens |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:40 pm | Regulatory Mechanisms of Bacterial Pathogens |
| Discussion Leader: Edward Geisinger (Tufts University) |
1:30 pm - 1:50 pm | Jeffrey Mellin (CIRAD - France)
"A Cobalamin riboswitch regulates a long antisense RNA in Listeria monocytogenes"
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1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Joseph Boll (University of Texas Southwestern)
"Involvement of the Flagellar MS- and C-Rings in the Regulatory Cascade that Influences Flagellar Gene Expression in Campylobacter jejuni" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 2:40 pm | Concluding Remarks: Zachary Dalebroux (University of Washington) and Aimee Richard (University of Pennsylvania) |
2:40 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |