| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Invasion and Dissemination
of Pathogens |
| Discussion Leader: Kimberly Davis (Tufts University School of Medicine, USA) |
| 3:45 pm - 3:50 pm | Opening Remarks |
| 3:50 pm - 4:05 pm | Samantha Prezioso (Emory University, USA)
"Direct and Indirect Impact of EftM on Pseudomonas aeruginosa Adhesion" |
| 4:05 pm - 4:10 pm | Discussion |
| 4:10 pm - 4:25 pm | Rebeccah Lijek (Harvard Medical School, USA)
"Chlamydia trachomatis Serovar-Specific Virulence Factors Drive Immunopathology" |
| 4:25 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Immunity and Inflammation During Infection |
| Discussion Leaders: Andrew Olive (University of Massachusetts Medical School, USA) and Lillian Juttukonda (Vanderbilt University, USA) |
| 7:30 pm - 7:45 pm | Jeannette Tenthorey (University of California, Berkeley, USA)
"Recognition of Multiple Motifs on Bacterial Ligands by NAIP Receptors Constrains Bacterial Immune Evasion" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Jonathan Lenz (University of Wisconsin-Madison, USA)
"Role for Neisseria gonorrhoeae LdcA in NOD1-Agonist Peptidoglycan Release and Effects on Inflammatory Responses in Human Blood and Fallopian Tube" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Mariana Byndloss (University of California, Davis, USA)
"PPARγ Signaling Mediates Colonization Resistance Against Escherichia coli" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Tobias Kerrinnes (University of California, Davis, USA)
"Host Cell Polyamine Synthesis Provides a Crucial Nutrient Source for Intracellular Growth and Persistence of Brucella abortus" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Matthew Hendricks (University of Pittsburgh School of Medicine, USA)
"Dysregulation of Nutritional Immunity During Respiratory Virus Infection Enhances Pseudomonas aeruginosa Biofilm Growth" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Aimee Wilde (Vanderbilt University, USA)
"Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Secretion Systems and Maintaining the Replicative Niche |
| Discussion Leaders: Kate Zulauf (University of North Carolina at Chapel Hill, USA) and Stephanie Shames (Yale University, USA) |
| 9:00 am - 9:15 am | Adelle McFarland (University of Washington, USA)
"Cyclic Dinucleotide Detection by RECON Controls Innate Immune Responses" |
| 9:15 am - 9:20 am | Discussion |
| 9:20 am - 9:35 am | Brandon Anjuwon-Foster (University of North Carolina at Chapel Hill, USA)
"A Genetic Switch Controls Flagellum Biosynthesis and Toxin Production in Clostridium difficile" |
| 9:35 am - 9:40 am | Discussion |
| 9:40 am - 9:55 am | James Grayczyk (Loyola University Chicago, USA)
"Staphylococcus aureus Suppression of Immune Responses via Metabolic Cofactors" |
| 9:55 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Troy Hubbard (Harvard Medical School, USA)
"Genetic Analysis of Vibrio parahaemolyticus Intestinal Colonization" |
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:35 am | Brian Russo (Massachusetts General Hospital, USA)
"Intermediate Filaments Enable Pathogen Docking to Trigger Type 3 Effector Translocation" |
| 10:35 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Kristin Kotewicz (Sackler School of Graduate Biomedical Sciences, Tufts University, USA)
"L. pneumophila Remodels Host ER Tubules via Bacterial Ubiquitin Editing Proteins" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Microbial Toxins |
| Discussion Leader: Walter Adams (Tufts University, USA) |
| 1:30 pm - 1:50 pm | Divya Balasubramanian (New York University School of Medicine, USA)
"Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes" |
| 1:50 pm - 1:55 pm | Discussion |
| 1:55 pm - 2:15 pm | Laura Ristow (University of Wisconsin-Madison, USA)
"Identification of a Host Receptor for Hemolysin from Uropathogenic Escherichia coli" |
| 2:15 pm - 2:20 pm | Discussion |
| 2:20 pm - 2:30 pm | Closing Remarks |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
