Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Polymicrobial Interactions in the Context of Disease
Discussion Leader: Michael Connor (Institut Pasteur, France)
3:45 pm - 4:00 pm
Lauren Radlinski (UC Davis, United States)
"Proton-Consuming Reactions Allow Salmonella to Overcome Colonization Resistance in the Gut"
4:00 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Matthew Munneke (Vanderbilt University, United States)
"Clostridioides difficile nucleobase scavenging in the competitive gut environment"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Host Response to Pathogens
Discussion Leader: Kara Eichelberger (Vanderbilt University Medical Center, United States)
7:30 pm - 7:50 pm
Rafael Rivera-Lugo (University of California Berkeley, United States)
"MAIT Cell Avoidance is a Determinant of Listeria monocytogenes Pathogenesis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Anna-Lisa Lawrence (University of Michigan, United States)
"Human Neutrophils Direct Epithelial Cell Extrusion to Enhance Intestinal Epithelial Host Defense during Salmonella Infection"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Vladimir Diaz-Ochoa (University of California, Davis, United States)
"Nutrition is Linked to to Immunity Against Bacterial Pathogens via the NRAMP1 Metal Transporter"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Justin Roncaioli (UC Berkeley, United States)
"Cell Death Pathways in Intestinal Epithelial Cells Define Mouse Resistance to Oral Shigella flexneri Challenge"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Overcoming the Stress of Host Invasion
Discussion Leader: Stephanie Lehman (National Institutes of Health, United States)
9:00 am - 9:20 am
Miro Thorsten Wilhelm Plum (University of Basel, Switzerland)
"Type VI Secretion System-5 of Burkholderia thailandensis Assembles to Lyse Host Cell Protrusions"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Rochelle Glover (University of Washington, United States)
"A Genome-Wide CRISPR-Cas9 Knockout Screen Reveals PTEN as a Novel Host Factor Required for Macrophage Infection by Listeria monocytogenes "
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Amanda Brady (University of Louisville, United States)
"Yersinia pestis Inhibits Host Synthesis of Leukotriene B4, a Potent Mediator of Inflammation"
10:20 am - 10:30 am
Discussion
10:30 am - 10:50 am
Zachary Resko (Loyola University Chicago, United States)
"Elucidating the Role of a Staphylococcal Glucosaminidase in Host Innate Immune Responses"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Toxins and Other Virulence Factors: The Diversity of Bacterial Weapons
Discussion Leader: Sean Callahan (University of Tennessee, United States)
1:30 pm - 1:45 pm
Brady Spencer (University of Colorado-Anschutz Medical Campus, United States)
"A Type VII Secretion System in Group B Streptococcus Mediates Cytotoxicity and Virulence"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Christopher Peritore-Galve (Vanderbilt University Medical Center, United States)
"Uncovering the pathophysiology of Clostridioides difficile -associated diarrhea"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Alexis Waller (UT Southwestern Medical Center, United States)
"Flagellar Filament Length Regulation in Polarly-Flagellated Pathogens"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes