Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Late-Breaking Topics
Discussion Leader: Thomas Fox (Cornell University, USA)
7:40 pm - 7:55 pm
Opening Remarks
7:55 pm - 8:15 pm
Introduction by Discussion Leader
8:15 pm - 8:35 pm
Martin Jonikas (Princeton University, USA)
"Structure and Biogenesis of the Eukaryotic CO2 -Concentrating Organelle, the Pyrenoid"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Selected from Poster Abstracts: Felix Boos (Technische Universität Kaiserslautern, Germany)
"The Mitochondrial Stress Response"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Nils-Goran Larsson (Karolinska Institutet, Sweden)
"Maintenance and Transmission of Mammalian mtDNA"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Evolution of Organelles
Discussion Leader: Andreas Weber (Heinrich Heine University Duesseldorf, Germany)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Thijs Ettema (Uppsala University, Sweden)
"The Symbiotic Origin of Eukaryotic Cells"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Eva Nowack (Heinrich Heine University Duesseldorf, Germany)
"The Transition from Bacterial Endosymbiont to Eukaryotic Organelle"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
Selected from Poster Abstracts: Pavel Doležal (Charles University, Czech Republic)
"Ancestral Mitochondrial Protein Secretion"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Selected from Poster Abstracts: Giel van Dooren (Australian National University, Australia)
"A Divergent Cytochrome c Oxidase in Apicomplexan Parasites"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
Yoshihisa Hirakawa (Faculty of Life and Environmental Sciences, University of Tsukuba, Japan)
"Evolution of Secondary Plastid-Bearing Algae"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Andre Schneider (University of Bern, Switzerland)
"Mitochondrial Biogenesis in Trypanosomatids: Variations on a Theme or Fundamentally Different?"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Doron Rapaport (University of Tuebingen, Germany)
"Independent Evolution of Functionally Exchangeable Mitochondrial Outer Membrane Import Complexes"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizers: Carla Koehler (University of California, Los Angeles, USA) and Christine Foyer (University of Leeds, United Kingdom)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Gene Expression in Organelles
Discussion Leader: Alice Barkan (University of Oregon, USA)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
Bob Lightowlers (Institute for Cell and Molecular Biosciences, Newcastle University, United Kingdom)
"Investigating the Complexities of Mitochondrial Protein Synthesis in Man"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Selected from Poster Abstracts: Brendan Battersby (University of Helsinki, Finland)
"Molecular Basis of C12orf65 Function in a Ribosome Rescue Pathway of Mitochondrial Protein Synthesis"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
Selected from Poster Abstracts: Philippe Giegé (Institute of Molecular Biology of Plants (IBMP), CNRS, France)
"Small Is Big in Arabidopsis Mitochondrial Ribosome"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Selected from Poster Abstracts: Felix Willmund (Technical University of Kaiserslautern, Germany)
"Ribosome Profiling Reveals Similarities and Differences in Chloroplast Protein Synthesis Between a Green Alga and Land Plants"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
Elena Rugarli (University of Cologne, Germany)
"CLUH Mediates Post-Transcriptional Regulation of Mitochondrial Metabolism"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Protein Import into Mitochondria and Chloroplasts
Discussion Leader: Carla Koehler (University of California, Los Angeles, USA)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Nikolaus Pfanner (University of Freiburg, Germany)
"Mitochondrial Machineries for Protein Translocation and Sorting"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Diana Stojanovski (Bio21 Institute, University of Melbourne, Australia)
"The Human TIM22 Complex: A Modern View of an Essential Mitochondrial Inner Membrane Insertase"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
Danny Schnell (Michigan State University, USA)
"Mechanism and Regulation of the Chloroplast Protein Import Machinery"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
Selected from Poster Abstracts: Danja Schuenemann (Ruhr-University Bochum, Germany)
"Analysis of the Interaction Between Ribosomes and the Signal Recognition Particle in Chloroplasts"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
Rong Li (Johns Hopkins University, USA)
"Mitochondria in Cytosolic Proteostasis and Cellular Aging"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Selected from Poster Abstracts: Carlo Vascotto (University of Warsaw, Poland)
"DNA Repair Protein APE1 Degrades Damaged Abasic mRNA in Human Mitochondria"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Ivan Tarassov (GMGM (UMR 7156), CNRS / University of Strasbourg, France)
"Mitochondrially Targeted Small Noncoding RNAs as a Tool to Influence Human Mitochondrial DNA"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Assembly of Organellar Protein Complexes: Proteins, Lipids and Cofactors
Discussion Leader: Antoni Barrientos (Miller School of Medicine, University of Miami, USA)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
Eric Shoubridge (McGill University, Canada)
"Interrogating the Mitochondrial Interactome Using BioID"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Selected from Poster Abstracts: Rachel Cox (Uniformed Services University of the Health Sciences, USA)
"Dynamics of Clu-Containing Bliss Particles as a Read-out of Mitochondrial Function"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Shu-Ou Shan (California Institute of Technology, USA)
"Structures and Functions of Protein Biogenesis Machineries"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Selected from Poster Abstracts: Lynn Richardson (Michigan State University, USA)
"Molecular Topology of the Transit Peptide During Chloroplast Protein Import"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Selected from Poster Abstracts: Caroline Dewar (University of Bern, Switzerland)
"Deciphering the Mitochondrial Quality Control Mechanism in Trypanosoma brucei "
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Signaling to and from Organelles
Discussion Leader: Ophry Pines (Hebrew University of Jerusalem, Israel)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Christine Foyer (University of Leeds, United Kingdom)
"The Role for Whirly1 in Chloroplast Development"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Jared Rutter (University of Utah / Howard Hughes Medical Institute, USA)
"Mitochondria, Metabolism and Cell Decisions: Entwined in Health and Disease"
10:05 am - 10:15 am
Discussion
10:15 am - 10:35 am
Jesse Woodson (University of Arizona, USA)
"Balancing Stress and Energy Production: Chloroplasts as Environmental Sensors"
10:35 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:25 am
Selected from Poster Abstracts: Chan Yul Yoo (University of California, Riverside, USA)
"Mechanism of Nucleus-to-Plastid Light Signaling for Initiating Chloroplast Biogenesis"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Selected from Poster Abstracts: Markus Teige (University of Vienna, Austria)
"Chloroplast Ca2+ -Signalling in Plastid Development and Stress Response"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Sebastian Hiller (University of Basel, Switzerland)
"Dynamic Chaperone-Client Interactions"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Abdussalam Azem (Tel Aviv University, Israel)
"Mitochondrial Protein Folding by Hsp70 System in Health and Disease"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Large Scale Organelle Biology
Discussion Leader: Sacha Baginsky (Martin Luther University of Halle-Wittenberg, Germany)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
Bettina Warscheid (University of Freiburg, Germany)
"Defining the Mitochondrial Proteome in a Cellular Context"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
Klaas Van Wijk (Cornell University, USA)
"Protease Networks of the Chloroplast"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
Selected from Poster Abstracts: Inge Kühl (Institute for Integrative Biology of the Cell (I2BC), CNRS, France)
"Hallmarks of Mitochondrial Dysfunction in Mouse Heart"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
Jan Riemer (University of Cologne, Germany)
"Cytosolic Quality Control in the Regulation of IMS Protein Import"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Organelle Dynamics
Discussion Leader: Benedikt Westermann (University of Bayreuth, Germany)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
Laura Lackner (Northwestern University, USA)
"Mitochondrial Anchors: Positioning Mitochondria and More"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
Heidi McBride (McGill University, Canada)
"Mechanisms of Mitochondrial Vesicle Formation"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
Selected from Poster Abstracts: Serena Schwenkert (Ludwig Maximilian University of Munich, Germany)
"Identifying Novel Factors in Chloroplast Biogenesis"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Selected from Poster Abstracts: Ellen Yeh (Stanford University, USA)
"1+1=1: A Forward Screen for Novel Plastid Biogenesis Genes in Malaria Parasites"
10:40 am - 10:45 am
Discussion
10:45 am - 11:15 am
Coffee Break
11:15 am - 11:35 am
Joerg Nickelsen (Ludwig Maximilian University of Munich, Germany)
"Spatial Organization of Thylakoid Membrane Biogenesis"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
Thomas Meier (Imperial College London, United Kingdom)
"Structure of Complete ATP Synthases from Yeast Mitochondria and Spinach Chloroplasts"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Derek Narendra (National Institutes of Health, USA)
"Parkinson-Related CHCHD2 Is Necessary for Oligomerization of ALS/FTD-Related CHCHD10"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Organelle Autophagy and Aging
Discussion Leader: Richard Youle (National Institute of Neurological Disorders and Stroke, NIH, USA)
6:00 pm - 6:15 pm
Introduction by Discussion Leader
6:15 pm - 6:35 pm
Konstanze Winklhofer (Institute for Biochemistry and Pathobiochemistry, Ruhr-University Bochum, Germany)
"Mitochondria as a Platform for Ubiquitin Signaling"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
Selected from Poster Abstracts: Elizabeth Vierling (University of Massachusetts Amherst, USA)
"The Mitochondrial mTERF and ATAD3 Proteins in Arabidopsis "
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
Masanori Izumi (Tohoku University, Japan)
"How Chlorophagy Is Executed: Induction and Intracellular Events"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
Selected from Poster Abstracts: Ingrid Lafontaine (UMR7141, CNRS / Sorbonne Université, France)
"Assessment of an Antimicrobial Origin of Chloroplast Targeting Peptides"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure