SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm | Site Director's remarks |
7:45 pm | Jean Vance (University of Alberta, Edmonton, Canada)
Chair's Welcome and Introduction |
7:55 pm - 9:30 pm | KONRAD BLOCH and EUGENE KENNEDY LECTURES |
| Discussion Leaders: Dennis E. Vance (University of Alberta, Edmonton) & Bill Dowhan (University of Texas, Houston) |
7:55 pm | Joseph Goldstein (University of Texas Southwestern, Dallas)
"The SREBP Pathway: Elucidation in Cultured Cells" |
8:35 pm | Michael Brown (University of Texas Southwestern, Dallas)
"The SREBP Pathway: Elucidation in Living Mice" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CHOLESTEROL METABOLISM |
| Discussion Leader: Laura Liscum (Tufts University, Boston) |
9:00 am | David Russell (University of Texas Southwestern, Dallas)
"Molecular Mechanisms of Cholesterol Turnover in the Brain" |
9:40 am | Daniel Ory (Washington University, St. Louis)
"Niemann-Pick C Disease Genes and Cholesterol Homeostasis" |
10:20 am | Short talk selected from abstracts |
10:30 am | Coffee Break / Photo |
10:50 am | Russell DeBose-Boyd (University of Texas Southwestern, Dallas)
"Delineating the Pathway for Sterol-Accelerated Degradation of Mammalian HMG-CoA Reductase" |
11:30 am | Randy Hampton (University of California San Diego)
"Regulation of Protein Stability by Lipid-Mediated Reversible Misfolding" |
12:10 pm | Short talk selected from abstracts |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | INTERORGANELLE LIPID TRANSPORT |
| Discussion Leader: Dennis Voelker (National Jewish Res. and Medical Center, Denver) |
7:30 pm | Masahiro Nishijima (National Inst. Infectious Diseases, Tokyo, Japan)
"Non-Vesicular Intracellular Trafficking of Ceramide by CERT" |
8:10 pm | Richard Pagano (Mayo Clinic and Foundation, Rochester)
"Coordinate Regulation of Caveolar Endocytosis and Secretory Processes by Sphingolipids and Cholesterol" |
8:50 pm | Gerrit van Meer (Utrecht University, the Netherlands)
"Fate and Function of Cellular Glycosphingolipids" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | PHOSPHOLIPID METABOLISM |
| Discussion Leader: Suzanne Jackowski (St. Jude Children's Research Hospital, Memphis) |
9:00 am | Howard Goldfine (University of Pennsylvania, Philadelphia)
"Bacterial Phospholipases in Host-Pathogen Interactions" |
9:40 am | Rosemary Cornell (Simon Fraser University, Vancouver, Canada)
"Activation of CTP:phosphocholine Cytidylyltransferase by Membrane Binding" |
10:20 am | Short talk selected from abstracts |
10:30 am | Coffee Break |
10:50 am | Neale Ridgway (Dalhousie University, Halifax, Canada)
"An Intranuclear Membrane System Regulated by CTP:phosphocholine Cytidylyltransferase and Phosphatidylcholine Synthesis" |
11:30 am | Arnold Strauss (Vanderbilt Children's Hospital, Nashville)
"Animal Models of a Human Mitochondrial Phospholipid Disorder: Barth's Syndrome" |
12:10 pm | Short talk selected from abstracts |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | FATTY ACID METABOLISM - 1 |
| Discussion Leader: Edward Dennis (University of California, San Diego) |
7:30 pm | Charles Martin (Rutgers University, New Jersey)
"Transcription and mRNA Stability: Regulation of Fatty Acid Desaturase Activities Through a Family of ER Membrane Proteins" |
8:10 pm | Thomas McIntyre (Cleveland Clinic, Cleveland)
"Metabolism of Oxidized Lipids and Mitochondrial Function" |
8:50 pm | William Smith (University of Michigan, Ann Arbor)
"Cyclooxygenases-1 and -2" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | FATTY ACID METABOLISM - 2 |
| Discussion Leader: Chuck Rock (St. Jude Children's Research Hospital, Memphis) |
9:00 am | John Cronan (University of Illinois, Urbana)
"ACP: New Stuff About an Old Protein" |
9:40 am | Diego de Mendoza (National University of Rosario, Argentina)
"Lipid Synthesis Regulated by a Transcription Factor Sensing Malonyl-CoA" |
10:20 am | Short talk selected from abstracts |
10:30 am | Coffee Break |
10:50 am | David Bernlohr (University of Minnesota, Minneapolis)
"Nutrient Sensing: Fatty Acid Transport in Adipocytes and Activation of AMP Kinase" |
11:30 am | James Ntambi (University of Wisconsin, Madison)
"Role of Stearoyl-CoA Desaturase in Lipid Metabolism" |
12:10 pm | Short talk selected from abstracts |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #2 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ABC TRANSPORTERS AND TRANSMEMBRANE LIPID FLUX |
| Discussion Leader: Chris Raetz (Duke University, Durham) |
7:30 pm | Peter Edwards (University of California Los Angeles)
"ABCG1: a Key Modulator of Lipid Flux" |
8:10 pm | Chip Davis (Schering-Plough Research Institute, Kenilworth)
"NPC1L1 Regulation of Intestinal Sterol Absorption" |
8:50 pm | Helen Hobbs (University of Texas Southwestern, Dallas)
"Trafficking of Dietary Cholesterol" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | TRIACYLGLYCEROL METABOLISM, OBESITY AND DIABETES |
| Discussion Leader: Rosalind Coleman (University of North Carolina, Chapel Hill) |
9:00 am | Dawn Brasaemle (Rutgers University, New Jersey)
"Lipid Droplet-Associated Proteins and the Control of Triacylglycerol Metabolism in Adipocytes" |
9:40 am | Karen Reue (University of California, Los Angeles)
"Lipin: a Modulator of Triglyceride Metabolism in Adipose Tissue and Muscle" |
10:20 am | Short talk selected from abstracts |
10:30 am | Coffee Break |
10:50 am | Hei-Sook Sul (University of California, Berkeley)
"Regulation of Fatty Acid and Fat Metabolism in Adipocytes" |
11:30 am | Chris Newgard (Duke University, Durham)
"Mechanisms of Lipid-Induced Tissue Failure in Diabetes" |
12:10 pm | Short talk selected from abstracts |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #2 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | TRANSCRIPTIONAL REGULATION OF LIPID METABOLISM |
| Discussion Leader: George Carman (Rutgers University, New Jersey) |
7:30 pm | Short talk selected from abstracts |
7:40 pm | Bruce Spiegelman (Dana Farber Cancer Inst., Harvard Univ., Boston)
"Regulation of Lipid and Energy Homeostasis Through the PGC-1 Transcriptional Co-activators" |
8:20 pm | Carl Sparrow (Merck, Rahway)
"The LXR Nuclear Receptor and the Cellular Response to Excess Cholesterol" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |