Regulation of the Structure and Function of Lipids and Lipid Metabolizing Enzymes in Signaling and Metabolism

The 2023 Molecular and Cellular Biology of Lipids Gordon Research Conference and Seminar will provide a platform for scientists from various sub-disciplines of lipid biology, biochemistry, and biophysics to present and discuss their most recent discoveries that impact the field. The overarching focus is on the “Regulation of the Structure and Function of Lipids and Lipid Metabolizing Enzymes in Signaling and Metabolism”. This focus reflects the unique aspects and incredible diversity of lipids and their associated enzymes in regulating signaling pathways, membrane environments, metabolic pathways, and gene transcription to affect physiology and pathophysiology. The diversity in both lipid type and distribution plethora is important to the various roles various lipids they play in these processes. Modulating the levels of various lipids in different organ and subcellular compartments requires specific regulation of various lipid metabolizing enzymes. These enzymes are unique in that their substrates are hydrophobic or at least amphipathic. This imposes special requirements for the regulation and chemistry underlying their function. This conference focuses on understanding how the structure, chemistry, and dynamic distribution and regulation of these enzymes modulate lipids to affect signaling and metabolism. Invited speakers will anchor nine plenary sessions, and we will select 14 of the 36 talks from the submitted abstracts to capture the most recent groundbreaking research. Daily poster sessions will encourage lively discussions and feedback. Overall, this conference is designed to attract a variety of lipid researchers focused on different areas of lipid research to foster a productive exchange of ideas and encourage collaborations. Enhancing these exchanges is the ambiance of Waterville Valley set in the White Mountain National Forest. Traditionally, the outdoor activities here stimulates a number of informal and productive discussions that serve to accelerate research leading to groundbreaking discoveries. These discoveries advance our understanding of the impact of lipid biochemistry and biophysics in physiology and pathophysiology.