Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: The Spatial Organization of Lipid Metabolism
Discussion Leader: Pushpendra Singh (Walter Reed Army Institute of Research / Henry M. Jackson Foundation, USA)
3:45 pm - 4:10 pm
Will Prinz (National Institutes of Health, USA)
"The Role of ER Membrane Contact Sites in Lipid Metabolism and Organelle Biogenesis"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Hanaa Hariri (University of Texas Southwestern Medical Center, USA)
"Regulation and Compartmentalization of Fatty Acid Metabolism"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Cellular Functions of Lipids
Discussion Leader: Mario Ruiz (University of Gothenburg, Sweden)
7:30 pm - 7:40 pm
Brooke Emerling (Sanford Burnham Prebys Medical Discovery Institute, USA)
"Targeting Non-Canonical Phosphoinositide Signaling for Metabolic Homeostasis"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Gregory Miner (University of North Carolina at Chapel Hill, USA)
"Mechanism of Lipid Droplet/Mitochondria Contacts and Role of Perilipin 5 in Lipid Metabolism"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Aastha Kumari (National Centre for Biological Sciences, Tata Institute of Fundamental Research, India)
"Unique Lipid Kinase Isoforms Tune PIP2 Resynthesis During G-Protein Coupled PLC Signaling In Vivo "
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Noah Steinfeld (University of Michigan, USA)
"Roles and Regulation of the Lipid Kinase, Vps34"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Ranjan Devkota (University of Gothenburg, Sweden)
"Membrane Fluidity Is Regulated by the C. elegans Transmembrane Protein FLD-1 and Its Human Homologs TLCD1/2"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Pushpendra Singh (Walter Reed Army Institute of Research / Henry M. Jackson Foundation, USA)
"Saturated Phospholipids Are Required for QS21-Induced Nano- to Micron-Size Transformation of Cholesterol-Containing Small Unilamellar Liposomes"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Jessica Gullett (St. Jude Children's Research Hospital, USA)
"The Role of Fatty Acid Binding Proteins in Gram Positive Pathogenic Bacteria"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Sarah Whaley (St. Jude Children's Research Hospital, USA)
"Is FabH Essential for the Initiation of Fatty Acid Synthesis in Staphylococcus aureus ?"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Nutrient Homeostasis in Health and Disease
Discussion Leader: Jahangir Iqbal (King Abdullah International Medical Research Center, Saudi Arabia)
9:00 am - 9:10 am
Scott Summers (University of Utah, USA)
"Ceramides: Intracellular Gauges of Lipid Excess"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Daniel Kelpsch (Carnegie Institution for Science, USA)
"A Whole Animal High-Throughput Screen to Identify Modulators of Atherogenic Lipoproteins"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Atefeh Rabiee (Stanford University, USA)
"Divergent Regulation of Adipogenesis and Insulin Sensitivity by the Timing and Order of CEBPB and CEBPA Levels"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Mario Ruiz (University of Gothenburg, Sweden)
"AdipoR1 and AdipoR2 Maintain Membrane Fluidity in Most Human Cell Types and Independently of Adiponectin"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Cunqi Ye (University of Texas Southwestern Medical Center, USA)
"Synthesis of Membrane Phospholipids Influences Redox Metabolism to Promote Cell Growth and Survival"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Kristen Johnson (University of Texas Southwestern Medical Center, USA)
"How Lipid Organization in Plasma Membranes Controls Cholesterol Homeostasis and Bacterial Infection"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Gerard Pernes (Baker Heart and Diabetes Institute, Australia)
"The Immune Cell Lipidome as a Defining Feature of the Cells of the Immune System"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Hema Adhikari (Duke University, USA)
"Discovery of PIP5K1A as a KRAS-Specific Therapeutic Vulnerability in RAS Mutant Cancers"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Starting a Young Investigator Career
Discussion Leader: Cunqi Ye (University of Texas Southwestern Medical Center, USA)
1:30 pm - 2:30 pm
Panel Discussion
Career Advice for Young Scientists
Rosalind Coleman (University of North Carolina at Chapel Hill, USA)
Judith Storch (Rutgers University, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
