SUNDAY |
2:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Molecular Bases of Neurological Diseases |
| Discussion Leader: Karl Herrup (HKUST) |
7:40 pm - 8:05 pm | Li-Huei Tsai (MIT)
"The Roles of DNA Double-Strand Breaks in Neurodegenerative Disease" |
8:05 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Virginia Lee (University of Pennsylvania)
"Cell-to-Cell Transmission of Neurodegenerative Disease Proteins: Insights from α-Synuclein in Parkinson's Disease" |
8:35 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Scott Brady (University of Illinois)
"Regulation of Axonal Transport and Pathogenesis in Adult Onset Neurodegeneration" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Short Talk #1: Jun Ding (Stanford University)
"Dynamic Synaptic Re-Organization in the Motor Cortex in Parkinson's Disease"
|
9:25 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Structural Bases of Synapse Formation |
| Discussion Leader: Eunjoon Kim (KAIST) |
9:00 am - 9:25 am | Lily Jan (UC San Francisco/HHMI)
"Ion Channels in Health and Disease" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Mingjie Zhang (HKUST)
"Phosphorylation-Dependent and -Independent Target Recognitions by MAGUK GK Domains" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Lin Mei (Georgia Regents University)
"LRP4 in Synapse Formation and Plasticity in Peripheral and Central Nervous Systems" |
10:35 am - 10:45 am | Discussion |
10:45 am - 11:00 am | Short Talk #2: Xiang Yu (Institute of Neuroscience)
"A Molecular Mechanism for Activity-Dependent, Competition-Based Spine Pruning"
|
11:00 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Group Photo / Coffee Break |
11:30 am - 12:20 pm | Keynote Lecture #1: Mu-Ming Poo (UC Berkeley)
"BDNF and Synaptic Plasticity" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Morphogenesis in Neural Development |
| Discussion Leader: Ron Yu (Stowers Institute for Medical Research) |
7:30 pm - 7:55 pm | Yuh Nung Jan (UC San Francisco/HHMI)
"Control of Neuronal Morphogenesis: From Form to Function to Regeneration" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Yimin Zou (UC San Diego)
"Signaling Mechanisms for Growth Cone Steering and Synapse Assembly" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Tomomi Shimogori (RIKEN Brain Science Institute)
"Molecular Mechanism of Circuit Development - Wiring of Thalamus and Cortex" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Short Talk #3: Sarah X. Luo (UC San Francisco)
"TGFβ and Synapse Homeostasis in Dopaminergic Neurons"
|
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Neural Development and Lineage Determination |
| Discussion Leader: Yi Sun (UCLA) |
9:00 am - 9:25 am | Arturo Alvarez-Buylla (UC San Francisco)
"Embryonic Origins of Postnatal Neural Stem Cell Specification" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | David Rowitch (UC San Francisco / HHMI)
"Astrocytes: Segmental Origins and Heterogeneous Functions" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:15 am | Short Talk #4: Chay Kuo (Duke University)
"Chemical Screen to Identify New Niche Components Sustaining SVZ Neurogenesis" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:35 am | Short Talk #5: Xuecai Ge (Stanford)
"Neuropilins Regulate Hedgehog Signal Transduction and Neurogenesis by Modulating cAMP Production and PKA Activity"
|
10:35 am - 10:40 am | Discussion |
10:40 am - 11:00 am | Coffee Break |
11:00 am - 11:25 am | Arnold Kriegstein (UC San Francisco)
"Molecular Motors and Gene Networks in Human Cortical Radial Glia" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Ulrich Mueller (The Scripps Research Institute)
"Lineage Origins of Glutamatergic Neurons in the Mammalian Neocortex" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:25 pm | Jeffrey Macklis (Harvard)
"Molecular Logic of Cortical Projection Neuron Development and Diversity" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Neural Circuit Development and Assembly |
| Discussion Leader: John Ngai (UC Berkeley) |
7:30 pm - 7:55 pm | Hongjun Song (Johns Hopkins University)
"Circuit Assembly During Adult Hippocampal Neurogenesis" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:30 pm | Rachel Wong (University of Washington)
"Circuit Assembly and Reassembly in the Vertebrate Retina" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:05 pm | Yi Zuo (UC Santa Cruz)
"Synapse Plasticity in the Motor Cortex" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Short Talk #6: Hideki Enomoto (Kobe University)
"Schwann Cell Precursors Undergo Neuronal Differentiation and Contribute to the Enteric Nervous System"
|
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Synaptic Diversity and Specification |
| Discussion Leader: Weichun Lin (UT Southwestern) |
9:00 am - 9:25 am | Peter Scheiffele (Biozentrum University of Basel)
"Neuronal Alternative Splicing Programs for Molecular Diversification" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Oliver Hobert (Columbia University/HHMI)
"Transcriptional Control of Synaptic Formation in C.elegans" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | H. Robert Horvitz (MIT/HHMI)
"The Conserved Protein VESA-1 Controls Synaptic Vesicle Acidification and Behavioral State" |
10:35 am - 10:45 am | Discussion |
10:45 am - 11:00 am | Short Talk #7: Simon Hippenmeyer (IST Austria)
"Unitary Production and Organization of Excitatory Neurons in the Neocortex" |
11:00 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Coffee Break |
11:30 am - 12:20 pm | Keynote Lecture #2: Thomas Südhof (Stanford University)
"Neurexin Diversity and Synapse Specification" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Neural Circuit Plasticity and Regeneration |
| Discussion Leader: Guo-Li Ming (Johns Hopkins University) |
7:30 pm - 7:55 pm | Kazuo Emoto (University of Tokyo)
"Sculpting Nociceptive Circuits in Drosophila" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Lu Chen (Stanford University)
"Molecular Mechanisms of Retinoic Acid-Mediated Synaptic Plasticity" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Zhigang He (Harvard University)
"Intrinsic Control of Axon Regeneration" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Short Talk #8: Yingxi Lin (MIT)
"A Novel Synaptic Mechanism in CA3 that is Critical for Contextual Memory Formation"
|
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Short Talk #9: Chun-Li Zhang (UT Southwestern)
"In vivo Reprogramming of Resident Astrocytes to Functional Neurons in the Adult Central Nervous System" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Neural Circuits and Behaviors |
| Discussion Leader: Yi Rao (Peking University) |
9:00 am - 9:25 am | Nirao Shah (UC San Francisco)
"Modular Molecular and Neural Control of Sexually Dimorphic Behaviors" |
9:25 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Toru Takumi (RIKEN Brain Science Institute)
"A Mouse Model of 15q Duplication Towards Understanding the Pathophysiology of Autistic Behavior" |
9:55 am - 10:00 am | Discussion |
10:00 am - 10:25 am | Yang Dan (UC Berkeley/HHMI)
"Neural Mechanisms for Sleep-Wake Control" |
10:25 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Coffee Break |
10:50 am - 11:15 am | Baoji Xu (The Scripps Research Institute Florida)
"Unraveling the CNS Pathways Regulating Body Weight" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Martha Constatine-Paton (MIT)
"A New Approach to Looking at the Roles of GluN2A and GluN2B in Developmental Plasticity" |
11:45 am - 11:50 am | Discussion |
11:50 am - 12:05 pm | Short Talk #10: Shernaz Bamji (University of British Columbia)
"Synaptic Adhesion Molecules in Learning and Memory"
|
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:25 pm | Short Talk #11: Christine Cho (Rockefeller University)
"An Interneuron Acts as Catalyst for Sensory Plasticity in Caenorhabditis elegans"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Mechanisms of Neurodegeneration and Regeneration |
| Discussion Leader: John Trojanowski (University of Pennsylvania) |
4:00 pm - 4:25 pm | Joseph Lewcock (Genentech)
"DLK-Dependent Regulation of the Neuronal Stress Response" |
4:25 pm - 4:30 pm | Discussion |
4:30 pm - 4:55 pm | Nancy Ip (HKUST)
"Targeting Synaptic Dysfunctions in Alzheimer's Disease"
|
4:55 pm - 5:00 pm | Discussion |
5:00 pm - 5:25 pm | Aaron Gitler (Stanford University)
"Genetic Interaction Between Two New Parkinson's Disease Genes" |
5:25 pm - 5:30 pm | Discussion |
5:30 pm - 5:55 pm | Cheng-Ting Chien (Academia Sinica)
"Dendrite Development and Degeneration Regulated by Leucine-Rich Repeat Kinases (Lrrk) and the Implication in Parkinson's Disease Pathogenesis" |
5:55 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |