Sunday
2:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Development of the Nervous System
Discussion Leader: Yishi Jin (University of California, San Diego, USA)
7:40 pm - 8:20 pm
Stephen Zipursky (University of California, Los Angeles, USA)
"In Search of Cajal's 'Unfathomable Mystery of Life'"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Kang Shen (Stanford University, USA)
"Coordination of Dendritic Development and Function in a Proprioceptive Neuron"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Tomomi Shimogori (RIKEN Center for Brain Science, Japan)
"Activity Dependent Btbd3 Protein Dynamics for Selective Dendrite Morphogenesis in Developing Neurons"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Synapses and Synaptic Development
Discussion Leader: Xiang Yu (Institute of Neuroscience, Chinese Academy of Sciences, China)
9:00 am - 9:20 am
Shernaz Bamji (University of British Columbia, Canada)
"Regulation of Synapse Formation and Plasticity by Palmitoylating Enzymes"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Cagla Eroglu (Duke University Medical Center, USA)
"How Do Astrocytes Sculpt Synaptic Circuits?"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 10:50 am
Mingjie Zhang (Hong Kong University of Science and Technology, Hong Kong SAR China)
"Postsynaptic Density Formation and Regulation via Phase Transition"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
Lu Chen (Stanford University, USA)
"Synaptic RA Signaling Mediates Experience-Dependent Hippocampal Function in Learning"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Thomas Sudhof (Stanford University, USA)
"Deconstructing Neuroligin Functions: Enduring Contradictions, Possible Solutions"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Selected from Poster Abstracts: Matthew Dalva (Thomas Jefferson University, USA)
"Synaptic Nanomodules Underlie the Organization and Plasticity of Spine Synapses"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Xin Duan (University of California, San Francisco, USA)
"Combinatorial Cadherins Guide the Assembly of Retinal Direction-Selective Circuits"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Neural Stem Cells and Development
Discussion Leader: Elva Diaz (UC Davis School of Medicine, USA)
7:30 pm - 7:50 pm
Christopher Walsh (Division of Genetics and Genomics, Boston Children's Hospital / Howard Hughes Medical Institute, USA)
"Somatic Mutation and Genomic Diversity in Human Cerebral Cortex"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Samantha Butler (University of California, Los Angeles, USA)
"Rethinking the Role of Netrin1 in Axon Guidance: Chemotaxis vs Haptotaxis?"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Selected from Poster Abstracts: Meng-meng Fu (Stanford University, USA)
"The Golgi Outpost Protein TPPP Is Critical for Myelination by Mediating Microtubule Growth in Oligodendrocytes"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Selected from Poster Abstracts: Hongyan Wang (Duke-NUS Medical School, Singapore)
"An Intrinsic Mechanism Controls Reactivation of Neural Stem Cells"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Marius Wernig (Stanford University, USA)
"Interrogating Autism Mutations in Human Neurons"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Circuits and Behavior
Discussion Leader: Jun Ding (Stanford University, USA)
9:00 am - 9:20 am
Yang Dan (University of California, Berkeley, USA)
"Neural Circuits Controlling Sleep"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Zhigang He (Harvard Medical School, USA)
"Dissecting the Function of Direct Corticospinal Projections"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Claire Wyart (Brain and Spine Institute (ICM), France)
"A Sensory Interface with the Cerebrospinal Fluid Modulates Function and Development of Motor Circuits in Vertebrates"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Mu-ming Poo (Institute of Neuroscience, Chinese Academy of Sciences, China)
"Learning-Associated Changes in Neuronal Population Dynamics"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Yuki Oka (California Institute of Technology, USA)
"The Organization of Neural Circuits Underlying Fluid Homeostasis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Selected from Poster Abstracts: Ishmail Abdus-Saboor (University of Pennsylvania, USA)
"A Mouse Pain Scale: Assessment of Pain Sensation in Mice Using Sub-Second Behavioral Mapping and Statistical Modeling"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Sarah Luo (Singapore Bioimaging Consortium, A*STAR, Singapore)
"Feeding Regulation by Tuberal Nucleus Somatostatin Neurons"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
2:00 pm - 4:00 pm
Poster Session
4:00 pm - 6:00 pm
Visualization and Analysis of the Connectome
Discussion Leader: Yimin Zou (University of California, San Diego, USA)
4:00 pm - 4:20 pm
Hongwei Dong (University of Southern California, USA)
"Molecular Neuroanatomy and Neural Networks of the Mouse Hippocampus"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 4:50 pm
Ann-Shyn Chiang (National Tsinghua University, Taiwan)
"Multiscale Anatomy of the Drosophila Connectome"
4:50 pm - 5:00 pm
Discussion
5:00 pm - 5:20 pm
Tianyi Mao (Vollum Institute, Oregon Health and Science University, USA)
"Integration of Multiple Connectomic Datasets for Analyzing Functional Circuits and Their Plasticity"
5:20 pm - 5:30 pm
Discussion
5:30 pm - 5:50 pm
Qingming Luo (Huazhong University of Science and Technology, China)
"Surveying and Mapping the Genetically Defined Brain-Wide Networks"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 7:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Genetic and Epigenetic Basis of Neuronal Identity and Function
Discussion Leader: Yi Sun (University of California, Los Angeles, USA)
9:00 am - 9:20 am
Hongkui Zeng (Allen Institute for Brain Science, USA)
"Cell Type Characterization and Circuit Mapping in the Mouse Cortex and Beyond"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Joseph Ecker (Salk Institute for Biological Studies / Howard Hughes Medical Institute, USA)
"Epigenomic Signatures of Neuron of Diversity in the Mammalian Brain"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Jens Hjerling Leffler (Karolinska Institutet, Sweden)
"Transcriptional Identification of Brain Cell Types and the Analysis of Disease"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
Ed Lein (Allen Institute for Brain Science, USA)
"Conserved and Specialized Features of Human Cortical Cell Types"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
Stavros Lomvardas (Columbia University, USA)
"Interchromosomal Genomic Interactions Regulate Olfactory Receptor Expression"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Selected from Poster Abstracts: Anita Thambirajah (University of Victoria, Canada)
"Transcriptomic Variations in the Developing Hippocampus Associate with Dynamic Histone Variant H2A.Z Deposition"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Xiaohong Xu (Institute of Neuroscience, Chinese Academy of Sciences, China)
"Regulation of Sexually Dimorphic Behaviors by the Medial Preoptic Area"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Sensory Systems
Discussion Leader: Nirao Shah (Stanford University, USA)
7:30 pm - 7:50 pm
Ardem Patapoutian (Scripps Research Institute / Howard Hughes Medical Institute, USA)
"Mechanotransduction: May the Force Be with You!"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Stephen Liberles (Harvard Medical School, USA)
"Internal Senses of the Vagus Nerve"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Lisa Stowers (The Scripps Research Institute, USA)
"Decoding Scent Marking Circuits: A Simple Model to Study Innate Olfactory Behavior"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Sandeep Robert Datta (Harvard Medical School, USA)
"Cortical Representations for the Olfactory World"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Disease Models of the Nervous System
Discussion Leader: Louis Reichardt (Simons Foundation, USA)
9:00 am - 9:20 am
Susan Ackerman (University of California, San Diego, USA)
"mRNA Translation Defects and Neurological Disorders"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Eric Huang (University of California, San Francisco, USA)
"Neuroimmune Interactions in Neurodegeneration: Lessons from Progranulin Deficiency"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Hailan Hu (Zhejiang University, China)
"Neural Mechanism of Depression"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
James Bibb (University of Alabama at Birmingham Medical Center, USA)
"Protein Phosphorylation in Reward and Aversion"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Selected from Poster Abstracts: Dong Yan (Duke University, USA)
"Function and Regulation of Antimicrobial Peptides in Ageing- and Infection-Associated Neurodegeneration"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Selected from Poster Abstracts: Polina Kosillo (University of California, Berkeley, USA)
"mTOR Is a Critical Molecular Regulator of Dopamine Neuron Function"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Selected from Poster Abstracts: Tong-Wey Koh (Temasek Life Sciences Laboratory, Singapore)
"Genetic Modifiers of Alpha-Synuclein in a Drosophila Parkinson's Disease Model"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Selected from Poster Abstracts: Simon Chen (University of Ottawa, Canada)
"Dissecting Neural Circuits Underlying Delayed Motor Learning Pathology in the 16p11.2 Deletion Mouse Model of Autism"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Keynote Session: Advanced Imaging Technologies in Neuroscience
Discussion Leader: Liqun Luo (Howard Hughes Medical Institute / Stanford University, USA)
4:00 pm - 4:40 pm
Xiaowei Zhuang (Harvard University / Howard Hughes Medical Institute, USA)
"Illuminating Neurobiology at the Nanoscale and Systems Scale by Imaging"
4:40 pm - 4:50 pm
Discussion
4:50 pm - 5:10 pm
Jin Hyung Lee (Stanford University, USA)
"Optogenetic fMRI and the Investigation of Global Brain Circuit Mechanisms"
5:10 pm - 5:20 pm
Discussion
5:20 pm - 5:30 pm
Selected from Poster Abstracts: Linlin Fan (Harvard University, USA)
"All-Optical Electrophysiology of Cortical Layer 1 Neurons In Vivo "
5:30 pm - 5:35 pm
Discussion
5:35 pm - 5:45 pm
Selected from Poster Abstracts: Subhojit Roy (University of Wisconsin-Madison, USA)
"Processive Movement by Biased Polymerization: A New Paradigm of Slow Axonal Transport Revealed by Super-Resolution Microscopy and Live Imaging"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:00 pm
Closing Remarks
6:00 pm - 7:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure