Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Integration of Neural Mechanisms
Discussion Leaders: Ismary Blanco (Georgetown University, United States) and Gilda Stefanelli (University of Toronto Mississauga, Canada)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
Anita Devineni (Emory University, United States)
"Mechanisms of Sensory Processing and Behavioral Flexibility in the Fly Taste System"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanisms of Neurological Disease
Discussion Leader: Yevheniia Ishchenko (Yale University, United States)
7:30 pm - 7:45 pm
Aileen Nava (UCLA, United States)
"Using OMICS Strategies to Identify Mechanisms Underlying the Neuropathology in Arboleda-Tham Syndrome and Related Chromatinopathies"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Andrii Kopach (National Institute of Neurological Disorders and Stroke, United States)
"TPPP Forms Liquid Condensates and Aggregates in Multiple System Atrophy"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Luke Bartelt (Duke University, United States)
"Purkinje-enriched snRNA-seq Reveals Synaptic Alterations in Spinocerebellar Ataxia Type 7 (SCA7)"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Mulatwa Haile (University of California Irvine, United States)
"Region and Cell type Specific Deletion of Neurexin-2 Causes Spontaneous Recurrent Seizures and ASD-like Behavior Impairments"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Wenjie Bian (Stanford University, United States)
"Developmental Role of Sleep in Shaping Social Interaction Behavior"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Yifei Cai (Yale University, United States)
"Spatial Proteomics and iPSC Modeling Uncover Mechanisms of Axonal Pathology in Alzheimer’s Disease"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Molecular Mechanisms, Neurodevelopment and Synaptic Signaling
Discussion Leader: Tyler Martinez (University of Colorado Anschutz Medical Campus, United States)
9:00 am - 9:15 am
Sarah Hill (National Institutes of Health (NIH/NINDS), United States)
"TDP-43 Represses Cryptic Exons in TFIIH Components to Regulate Epigenetic Remodeling at Neuronal Enhancers"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Hannah Shoenhard (University of Pennsylvania, United States)
"The Calcium-Sensing Receptor (CaSR) Regulates Zebrafish Sensorimotor Decision-Making Via a Genetically Defined Cluster of Hindbrain Neurons"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Michael Ratz (Karolinska Institute, Sweden)
"Next-Generation Lineage Tracing with Single-Cell and Spatial Transcriptomics"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
Norjin Zolboot (The Scripps Research Institute, CA, United States)
"Size Doesn't Matter: Macro Roles for MicroRNAs in Cerebellar Purkinje Cell Development"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
Haani Jafri (Thomas Jefferson University, United States)
"Quantal Synaptic Events in Single Dendritic Spines"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
Francisco Blanco (Baylor College of Medicine, United States)
"Tiam1 Modulates Hippocampal-Dependent Learning and Memory by Restricting the Structural and Functional Plasticity of Dentate Granule Cell Synapses"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
New Tools in Neuroscience
Discussion Leaders: Xin Jiang (MassGeneral Hospital/Harvard Medical School, United States)
1:30 pm - 1:45 pm
Jessie Brunner (Vrije Universiteit Amsterdam, The Netherlands)
"Power and Optimal Study Design in iPSC-Based Brain Disease Modelling"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Surya Aryal (University of Kentucky, United States)
"Single Molecule Fluorescence Imaging to Study Nicotinic Acetylcholine Receptors in the Brain"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Federico Zampa (The Scripps research institute, United States)
"Ribo-STAMPing the neuronal translatome"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
