SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
4:00 - 6:00 pm | Informal Welcome Reception and Poster Presentations (A) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Functional Tumor Lymphangiogenesis vs. Invasion |
| Discussion Leader: Kari Alitalo |
| Michael Pepper Lymphangiogenesis and Tumor Metastasis |
| Rakesh K. Jain Formation and Function of Tumor-Associated Lymphatics |
| Mihaela Skobe Mechanisms of Lymphatic Metastasis |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Molecular Mechanisms of Lymphangiogenesis |
| Discussion Leader: Jorg Wilting |
| Kari Alitalo Recent insight into lymphedema and lymphatic metastasis |
| Michael Detmar Molecular Mechanisms of Lymph Vessel Formation |
| Marika Karkkainen VEGF-C in Embryonic and Postnatal Lymphangiogenesis |
| Marc Achen Molecular Mechanisms Regulating Lymphangiogenesis |
| Miikka Vikkula
Molecular Genetics of Lymphedema
|
12:30 pm | Lunch Lymphatic Research Foundation Grants and Awards Program |
4:00 pm - 6:00 pm | Announcement of Young Investigator Awards
Poster Presentations (A)
|
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mechanisms of Lymphatic Metastasis |
| Discussion Leader: Mihaela Skobe |
| Gerhard Christofori Distinct Mechanisms of Tumor Metastasis |
| David Bates Lymphangiogenesis in Skin Cancer |
| Shahin Rafii Role of Marrow Derived Lymphatic Endothelial Progenitors in the Regulation of Tumor Growth and Metastasis |
| Toshio Ohhashi Biological Properties of Lymph Vessels Governing Lymphatic Metastasis of Carcinoma Cells and Lymphangiogenesis |
9:30 pm | Informal Reception sponsored by Lymphatic Research Foundation |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of Lymph Formation and Propulsion |
| Discussion Leader: Neil Granger |
| Daniela Negrini Mechanics of the Initial Lymphatics |
| Geert Schmid-Schönbein The Requirement and Mechanisms for Unidirectionality in Lymphatic Endothelial Cells |
| Pierre-Yves von der Weid
The Basis of Spontaneous Lymphatic Vessel Pumping
|
| Noel McHale Mechanism of Pacemaking in Lymphatic Vessels |
| David Zawieja Molecular Mechanisms Involved in Lymphatic Muscle Contraction |
| Miles Johnston
Lymphatic Transport of Cerebrospinal Fluid |
12:30 pm | Lunch Lymphatic Research and the National Institutes of Health: Past, Present, Future - Stephen Goldman, PhD, National Institutes of Health (NHLBI)
Following lunch there will be an informal Q&A session with Dr. Goldman for all interested parties |
4:00 pm - 6:00 pm | Poster Presentations (B) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Role of the Interstitium in Lymphatic Biology |
| Discussion Leader: Geert Schmidt-Schonbein |
| Melody Swartz Interplay Between Physical and Biochemical Mediators of Lymphangiogenesis |
| David Jackson Insights into Lymphatic Biology from the HA-Receptor LYVE-1 |
| Vincent Hascall Hyaluronan-Based Matrices Promote Leukocyte Adhesion and Activation in Inflammatory Responses |
| Rolf Reed Capillary-Interstitial-Lymphatic Interaction |
| Lee Leak New Approaches to Proteomic Analysis of Lymphangiogenesis |
9:30 pm | Informal Reception sponsored by Lymphatic Research Foundation |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Biomolecular Modulators of Lymphatic Development |
| Discussion Leader: David Bates |
| Guillermo Oliver Transcriptional Regulation in Developmental Lymphangiogenesis |
| Gavin Thurston Angiopoietin and Lymphatics |
| Jan Kitajewski Notch Function in Vascular Development |
| Jörg Wilting Cellular and Molecular Mechanisms of Embryonic Lymphangiogenesis: Clinical Implications |
| Thomas W. Glover Foxc2 and Lymphatic Abnormalities in Humans and Mice |
| Farhad Abtahian
Separation of Blood and Lymphatic Vascular Networks
|
12:30 pm | Lunch |
6:00 pm | Dinner |
7:00 pm | Business Meeting (mandatory for all attendees) |
7:30 pm - 9:30 pm | Lymphatic-Related Pathogenesis |
| Discussion Leader: Stan Rockson |
| Peter Mortimer Characterisation of Phenotypic Abnormalities in Primary Lymphoedema |
| Edwin A. Deitch Mesenteric Lymphatics: The Link Between the Ischemic Gut and the Development of Organ Failure |
| Don Ganem Pathogenesis of Kaposi’s Sarcoma, a Viral Infection of Lymphatic Endothelium |
| Dontscho Kerjaschki The Membrane Mucoprotein Podoplanin: From Renal to Lymphovascular Pathology |
| Steven Fishman Clinical Manifestations and Current Management of Lymphatic Anomalies |
| Patrick Tso
The Use of Lymph Fistula Mouse Model to Study Intestinal Lipid and Lipoprotein Metabolism |
9:30 pm | Informal Reception sponsored by Lymphatic Research Foundation |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Immune Cells, Inflammation, and the Lymphatics |
| Discussion Leader: Peter Mortimer |
| Gwendalyn J. Randolph Dendritic Cell Migration via Lymphatic Vessels |
| Donald McDonald Lymphangiogenesis in Chronic Inflammation |
| Caroline M. Pond Local Interactions Between Lymphoid and Adipose Tissues: Their Natural Functions and Role in the HIV-Related Adipose Redistribution Syndrome |
| Soichiro Miura In Vivo Demonstration of Lymphoid Cell Trafficking into and from the Intestine |
| Waldemar Olszewski
"De Novo" Formation Of Lymphoid Tissue In Adults - Antigen Stimulation, Cell Recruitment And Functional Organization |
12:30 pm | Lunch |
| Optional excursions (at your own expense - sign-up sheets will be provided)
We anticipate excursions for wine-tasting and whale watching; details to be provided at registration |
6:00 pm | Dinner |
7:30 pm - 8:00 pm | Presentations by the Andrew Moisoff Young Investigator Award Recipients (Lymphatic Research Foundation) |
| (TBA) |
8:00 pm - 9:30 pm | Keynote Address |
| Peter Carmeliet |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |