| Session 1 |
Sunday Evening |
| Introductory Talk |
| 7:30 p.m. |
Leader: Staffan Normark - Karolinska Institute
Microbial Pathogenesis and Innate Defenses
|
| Innate Immune Responses to Microbial Pathogens |
| 8:10 p.m. |
Emil Unanue - Washington University
Antigen processing and presentation in normal and SCID mice |
| 8:50 p.m. |
Break |
| Host and Microbial Developmental Pathways |
| 9:00 p.m. |
Jeff Gordon - Washington University
Effect of Microbial Colonization on Host Development |
| Session 2 |
Monday Morning |
| Bacterial Secretion of Virulence Factors |
| 9:00 a.m. |
Photo Session |
| 9:15 a.m. |
Leader: Joseph St. Geme - Washington University
Secretion of Haemophilus non-pilus adhesins |
| 9:50 a.m. |
Olaf Schneewind - U.C.L.A.
Type III Secretion |
| 10:25 a.m. |
Ralph Isberg - Tufts University
Secretion in Intracellular Legionella |
| 11:00 a.m. |
Coffee Break |
| 11:20 a.m. |
Peter Christie - University of Texas
Type IV Secretion |
| 12:00 |
Françoise Jacob-Dubuisson - Institut Pasteur-de Lille
FHA secretion in Bordetella |
| Session 3 |
Monday Evening |
| Translocation of Virulence Factors into Eukaryotic cells |
| 7:30 p.m. |
Leader: Hans Wolf-Watz - Umeå University
Mechanism of Translocation of Yop Proteins |
| 8:10 p.m. |
Clarence Kado - UC-Davis
Pilus-Mediated Translocation of Virulence Factors into Plant Cells |
| 8:50 p.m. |
Break |
| 9:00 p.m. |
Patricia Zambryski - Berkeley
T-DNA Translocation |
| Session 4 |
Tuesday Morning |
| Intracellular Action of Translocated Virulence Factors |
| 9:00 a.m. |
Leader: Jorge Galán - Yale
Type III Secretion in Salmonella |
| 9:40 a.m. |
Vassilis Koronakis - Cambridge
Nucleation and Bundling of Actin Salmonella |
| 10:20 a.m. |
Ulla Bonas - University of Halle
Avr Proteins |
| 11:00 a.m. |
Break |
| 11:20 a.m. |
Bruno Rouot - Montepellier University
Intracellular Action of Yops |
| 12:00 |
Christoph Dehio - Max Planck-Tübingen
Bartonella |
| Session 5 |
Tuesday Evening |
| Pathogen-induced Responses in Host Cells |
| 7:30 p.m. |
Leader: Philippe Sansonetti - Institut Pasteur
Mechanism of Action of Ipa's in Shigella |
| 8:10 p.m. |
Mary Beth Mudgett - Berkeley
HR Reactions in Plants |
| 8:45 p.m. |
Break |
| 9:00 p.m. |
Matthew Mulvey - Washington University
Innate Host Defenses Triggered by Uropathogenic E. coli |
| 9:35 p.m. |
Agneta Richter - Karolinska Institute
Hemolysin-Induced Oscillatory Calcium Response |
| Session 6 |
Wednesday Morning |
| Structural Basis of Organelle Biogenesis in Microbes |
| 9:00 a.m. |
Leader: Colin Hughes - Cambridge
Flagellum Assembly and Swarming |
| 9:30 a.m. |
Virginia Miller - Washington University
The Flagellar Basal Body - A New Pathway for the Export of Virulence Determinants |
| 10:00 a.m. |
Stefan Knight - Uppsala University
Structure-Function of Bacterial Adhesins |
| 10:35 a.m. |
Fredric Sauer - Washington University
Structural Basis of Pilus Assembly: Donor Strand Complementation |
| 10:55 a.m. |
Break |
| 11:15 a.m. |
Katrina Forest - University of Wisconsin
Structural Analysis of Type 4 Pili |
| 11:45 a.m. |
Joseph Lutkenhaus - Kansas University
Bacterial Cell Division |
| 1:00 - 5:00 |
Sailing Excursion |
| Session 7 |
Wednesday Evening |
| Molecular Cross Talk and Environmental Sensing |
| 7:30 p.m. |
Leader: Mike Caparon - Washington University
Environmental Sensing Pathways in Streptococcus |
| 8:10 p.m. |
Tom Silhavy - Princeton
Cpx: Global Regulator of the Attached State in E. coli |
| 8:50 p.m. |
Break |
| 9:05 p.m. |
Dale Kaiser - Stanford University
Social motility of Myxococcus |
| Session 8 |
Thursday Morning |
| Host-Pathogen Interactions |
| 9:00 a.m. |
Leader: Soman Abraham - Duke University
E. coli Interactions with Host Immune Cells |
| 9:40 a.m. |
Elaine Tuomanen - St. Jude's
Pneumococcal Signaling to Host Cells |
| 10:20 a.m. |
Hank Seifert - Northwestern University
Antigenic Variation in Neiserria |
| 11:00 a.m. |
Break |
| 11:20 a.m. |
James Kaper - University of Maryland
New Paradigms in Type 4 Pili and Type III Secretion |
| 12:00 p.m. |
Mike Koomey - Norway
Biogenesis of Type 4 pili: Twitching Motility |
| 12:15 p.m. |
Matthieu Arlat - Toulouse
Contact Induced Expression of Hrp Genes in Ralstonia |
| Session 9 |
Thursday Evening |
| Pathogen Attachment and Infection |
| 7:30 p.m. |
Leader: Brett Finlay - University of British Columbia
EPEC Colonization and Signaling |
| 8:10 p.m. |
Xavier Nassif - Institut Pasteur
Neiserria Colonization |
| 8:50 p.m. |
Break |
| 9:00 p.m. |
Gary Schoolnik - Stanford University
Function of type 4 pili in EPEC |
