| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MODEL SYSTEMS TO STUDY HOST/PATHOGEN INTERACTIONS |
| Discussion Leader: Fred Ausubel (Harvard University) |
| 7:30 pm - 8:00 pm | Bruno Lemaitre (CNRS)
"Drosophila as a model organism to study host-pathogen interactions and innate immunity" |
| 8:00 pm - 8:30 pm | Fred Ausubel (Harvard University)
"Signaling Pathways in the C. elegans Innate Immune Response" |
| 8:30 pm - 9:00 pm | Serap Aksoy (Yale University)
"The endocellular obligate symbiont of tsetse flies, Wigglesworthia glossinidia: a model for host-bacteria interactions" |
| 9:00 pm - 9:30 pm | Jean-Laurent Casanova (INSERM)
"Genetic dissection of immunity to infection: the human model" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CLOSE ENCOUNTERS WITH THE EPITHELIUM: ATTACHMENT AND INTERNALIZATION |
| Discussion Leader: Roy Curtiss III (Washington University) |
| 9:00 am - 9:30 am | Scott Hultgren (Washington University)
"Intracellular Bacterial Biofilm-like Pods in Urinary Tract Infections" |
| 9:30 am - 10:00 am | B. Brett Finlay (University of British Columbia)
"Global analysis of pathogenic E. coli/Citrobacter virulence genes" |
| 10:00 am | Coffee Break / Group Photo |
| 10:30 am - 11:00 am | Pascal Cossart (Institut Pasteur)
"Spatio-temporal exploitation of the cytoskeleton plasticity during entry of Listeria monocytogenes into mammalian cells" |
| 11:00 am - 11:30 am | Guy Tran Van Nhieu (Institut Pasteur)
"Signals and channels during Shigella invasion of epithelial cells" |
| 11:30 am - 12:00 pm | Sandrine Bourdoulous (CNRS)
"Signaling events induced in human endothelial cells following pilus-mediated adhesion of Neisseria meningitidis" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SURVIVING WITHIN CELLS: HOW TO BEAT TRAFFIC |
| Discussion Leader: Ralph Isberg (Tufts University) |
| 7:30 pm - 8:00 pm | David Russell (Cornell University)
"Why intracellular parasitism is not a degrading experience for Mycobacterium" |
| 8:00 pm - 8:30 pm | Craig Roy (Yale University)
"Cellular and immunological studies on Legionella phagosome transport" |
| 8:30 pm - 9:00 pm | Ralph Isberg (Tufts University)
"The dirty two dozen: a few minutes of life and death decisions made by L. pneumophila" |
| 9:00 pm - 9:30 pm | David Holden (Imperial College)
"Intracellular activities of Salmonella" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MICROBIAL LIFE IN COMMUNITY: BIOFILMS, QUORUM SENSING, COMMENSALISM |
| Discussion Leader: Roberto Kolter (Harvard University, Boston) |
| 9:00 am - 9:30 am | Soeren Molin (Technical University of Denmark)
"Steps in the development of microbial biofilms" |
| 9:30 am - 10:00 am | Roberto Kolter (Harvard University)
"Holding it all together in surface-associated bacterial communities" |
| 10:00 am | Coffee Break |
| 10:30 am - 11:00 am | Bonnie Bassler (Princeton University)
"Multiple Quorum Sensing Systems Converge to Control Virulence in Vibrio cholerae" |
| 11:00 am - 11:30 am | Paul Kolenbrander (NIH)
"Mixed-Species Communication Among Oral Bacteria" |
| 11:30 am - 12:00 pm | Lora V. Hooper (Washington University)
"How commensal bacteria shape innate immunity in the gut" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MODULATION OF HOST CELL VITAL PROCESSES BY MICROBIAL PATHOGENS |
| Discussion Leader: Jack Dixon (University of California, San Diego) |
| 7:30 pm - 8:00 pm | David Relman (Stanford University)
"Genome-wide patterns of response to infection: finding meaning amidst the 'chatter'" |
| 8:00 pm - 8:30 pm | Jack Dixon (UCSD)
"The YopT Super-Family of Cysteine Proteases: Their Roles in Animal and Plant Pathogensis" |
| 8:30 pm - 9:00 pm | Lorraine Hernandez (Yale University, New Haven)
"Salmonella-induced programmed cell death in macrophages" |
| 9:00 pm - 9:30 pm | Thomas Rudel (Max Planck Institute)
"Modulation of host cell apoptosis by bacterial infection" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MODULATION OF INNATE IMMUNITY OUTPUTS BY MICROBIAL PATHOGENS* |
| Discussion Leader: Staffan Normark (Karolinska Institute) |
| 9:00 am - 9:30 am | Ruslan Medzitov (Yale University)
"Toll pathway of host defense" |
| 9:30 am - 10:00 am | Bruce Beutler (The Scripps Research Institute)
"Forward Genetic Analysis of Innate Immunity" |
| 10:00 am | Coffee Break |
| 10:15 am - 10:45 am | Dana Philpott (Institute Pasteur)
"Nod1 and innate immunity to Helicobacter pylori infection" |
| 10:45 am - 11:15 am | J.M. Schroeder (University of Kiel)
"Adherent Bacteria as Inducers of Epithelial Antimicrobial Peptides and Proteins" |
| 11:15 am - 11:45 am | Staffan Normark (Karolinska Institute)
"Innate immune responses at epithelial linings and bacterial invasion" |
| 11:45 am - 12:15 pm | Sam Miller (University of Washington)
"Bacterial Innate Immunity" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CELL BIOLOGY OF ACQUIRED IMMUNITY TO MICROBIAL PATHOGENS * |
| Discussion Leader: Stefan Kaufmann (Max Planck Institute) |
| 7:30 pm - 8:00 pm | Eric Pamer (Memorial SloanKettering Cancer Center)
"Innate and adaptive immune responses to Listeria infection" |
| 8:00 pm - 8:30 pm | Leo Lefrançois (University of Connecticut)
"Migration and function of pathogen-specific T cells" |
| 8:30 pm - 9:00 pm | Mari-Jo Wick (Göteborg University)
"Innate and adaptive immunity to Salmonella" |
| 9:00 pm - 9:30 pm | Stefan Kaufmann (Max Planck Institute)
"Cellular and Molecular Crosstalk between Mycobacterium tuberculosis and Host Cells" |
| * Note: These sections have been made possible thanks to the generous support of The Ellison Foundation |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | INTERACTION OF PATHOGENS WITH POLYMORPHONUCLEAR CELLS AND MACROPHAGES |
| Discussion Leader: Guy Cornelis (University of Basel) |
| 9:00 am - 9:30 am | Arturo Zychlinsky (Max Planck Institute)
"Neutrophils in bacterial infections" |
| 9:30 am - 10:00 am | Carl Nathan (Cornell University)
"Defenses of Mycobacterium tuberculosis against macrophages" |
| 10:00 am | Coffee Break |
| 10:30 am - 11:00 am | Anthony Segal (University College London)
"Do ROS and reactive halides really kill microbes in the phagocytic vacuole? Almost certainly not!" |
| 11:00 am - 11:30 am | Jerold Weiss (University of Iowa College of Medicine)
"Molecular determinants of destruction and persistence of S. aureus within human neutrophils" |
| 11:30 am - 12:00 pm | Guy Cornelis (University of Basel)
"Yersinia: from Yscs to Yops" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | AGENTS OF BIOTERRORISM: THE CELL BIOLOGY OF INFECTION |
| Discussion Leader: John Young (The Scripps Research Institute) |
| 7:30 pm - 8:00 pm | John Young (The Salk Institute)
"Anthrax toxin-receptor interactions" |
| 8:00 pm - 8:30 pm | Stephen Leppla (NIH/NIDCR)
"Anthrax toxin" |
| 8:30 pm - 9:00 pm | Susan Straley (University of Kentucky)
"Pathogenesis of plague: the role of YopM" |
| 9:00 pm - 9:30 pm | Jean-Pierre Gorvel (INSERM)
"Modulation of the Immune response and evasion of macrophage killing by Brucella" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
