| Sunday Evening |
| Protein Translocation |
| Chair: Peter Novick |
| 7.30-7.45 | Welcome and Introduction |
| 7:45-8:20 | Walter Neupert
Translocation of proteins across and into the membranes of mitochondria |
| 8:20-8:55 | Reid Gilmore
Transfer of ribosomes from the SRP to the Sec61 complex |
| 8:55-9:20 | Ramanujan Hedge
The encoding of functional diversity in N-terminal signal sequences |
| Monday Morning |
| Translocation and folding |
| Chair: Ineke Braakman |
| 8:30-9:00 | Group Photograph |
| 9:00-9:35 | Suresh Subramani
Assembly and dynamics of the peroxisomal matrix protein import machinery |
| 9:35-10:10 | Chris Kaiser
Pathways for disulfide transfer in the endoplasmic reticulum |
| 10.10-10.40 | Coffee |
| 10:40-11:15 | Tom Rapoport
Protein Disulfide Isomerase Acts as a Redox-dependent Chaperone to Unfold Cholera Toxin |
| 11:15-11:50 | Ari Helenius
Close-up View of the Calnexin/Calreticulin Cycle |
| 11:50-12:25 | Randy Schekman
Domains of Sec24p involved in cargo sorting into COPII vesicles |
| Monday Evening |
| Vesicle Budding |
| Chair: Mike Roth |
| 7:30-7:55 | Charles Barlowe
Mechanisms of COPII dependent transport |
| 7:55-8:30 | Juan Bonifacino
Role of the GGAs in protein sorting at the TGN |
| 8:30-9:05 | Suzanne Pfeffer
Role for Rabs in Cargo selection in endosome-TGN transport |
| 9:05-9:40 | Sandra Schmid
Molecular Mechanisms Regulating Receptor-mediated Endocytosis |
| Tuesday Morning |
| Vesicle Targeting |
| Chair: Jennifer Lippincott-Schwartz |
| 9:00-9:35 | Susan Ferro-Novick
Tethering of ER-derived vesicles to the Golgi |
| 9:35-10:10 | Bill Balch
GTPase Regulation of ER Export |
| 10:10-10:45 | Hugh Pelham
The late Golgi compartment in yeast: entry and exit |
| 10:45-11:15 | Coffee |
| 11:15-11:50 | Graham Warren
Golgi transport and biogenesis |
| 11:50-12:25 | William Wickner
Mechanisms of homotypic vacuole fusion |
| Tuesday Evening |
| Membrane/Cytoskeletal Interactions |
| Chair: Janet Shaw |
| 7:30-8:05 | David Drubin
Roles for the actin cytoskeleton in endocytosis |
| 8:05-8:40 | Trina Schroer
Cytoplasmic dynein, dynactin and cytoplasmic organization |
| 8:40-9:15 | Julie Donaldson
Polyphosphoinositide turnover and Arf6-regulated membrane traffic |
| 9:15-9:50 | Lois Weisman
Identification of an organelle-specific myosin V receptor |
| Wednesday Morning |
| Protein/Lipid Interaction |
| Chair: Sean Munro |
| 9:00-9:35 | Scott Emr
Phosphoinositide- and ubiquitin-dependent protein sorting at the prevacuolar endosome in yeast |
| 9:35-10:10 | Antonella de Matteis
Role of PI4Kb in membrane trafficking |
| 10:10-10:45 | Marino Zerial
Rab GTPases and their effectors in the compartmental organization and function of early endosomes |
| 10.45-11:10 | Coffee |
| 11:10-11.45 | Silvia Corvera
PI3-kinase comes to life: early endsome dynamics visualized by high-speed Microscopy |
| 11.45-12:20 | Vytas Bankaitis
Phosphatidylinositol transfer protein function in eukaryote |
| Wednesday Evening |
| New Structures |
| Chair: Gerry Waters |
| 7.30-8.05 | Axel Brunger
Recent structural and biophysical studies of vesicle fusion proteins |
| 8.05-8.30 | Fred Hughson
Regulated assembly and refolding of membrane fusion proteins |
| 8.30-9.05 | Frances Brodsky
Structure-function analysis of a novel clathrin homologue |
| 9.05-9.40 | Jonathan Goldberg
GTPase structure and function at the Golgi |
| Thursday Morning |
| Synaptic cycle |
| Chair: Peter Arvan |
| 9:00-9:35 | Thomas Sudhof
The enigmatic functions of sec1/munc18-like proteins in membrane fusion |
| 9.35-10.10 | Reg Kelly
Linking endocytosis to exocytosis in neurons |
| 10:10-10:40 | Coffee |
| 10:40-11:15 | Pietro DeCamilli
Phosphoinositides and actin in clathrin-mediated endocytosis at the synapse |
| 11:15-11:50 | Dennis Selkoe
Intramembranous Proteolysis of Notch and APP and the Origin of Alzheimer's Disease |
| 11:50-12:15 | Andreas Meyer
Vacuole fusion: linking NSF dependent SNARE activation to the V-ATPase V0 sector |
| 12:15-12:30 | Peter van der Sluijs
Rabaptin4 directly interacts with gamma-adaptin on early endosomes and regulates membrane recycling |
| Thursday Evening |
| Polarity and Signalling |
| Chair: Jennifer Stow |
| 7.30-8.05 | Ira Mellman
Conventional and unconventional mechanisms of epithelial cell polarity |
| 8:05-8:40 | Rob Parton
Caveolae and Caveolins; linking cholesterol and signal transduction |
| 8:40-9:05 | Sean Munro
PtdIns(4)P dependent targeting of PH domains to the Golgi apparatus |
| 9:05-9:30 | Todd Graham
Requirement for an integral membrane P-type ATPase in clathrin-coated vesicle budding from the trans-Golgi network |
