| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Molecular Membrane Biology: A Twenty-Year Perspective |
| Discussion Leader: Jennifer Lippincott-Schwartz (NICHD, NIH, Bethesda, MD) |
| 7:30 pm - 8:30 pm | James Rothman (Sloan-Kettering, NYC, NY)
"Recent Studies of Membrane Fusion" |
| 8:30 pm - 9:30 pm | Michael Brown (UTSW Medical Center, Dallas, TX)
"Traveling with Membranes: A 30 Year Journey" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Coat Protein Dynamics: its Roles and Regulation |
| Discussion leader: Charlie Barlowe (Dartmouth Univ., Dartmouth, NH) |
| Randy Schekman (UC Berkeley, Berkeley, CA)
"Sec24p displays multiple sites for COPII cargo protein discrimination" |
| Bruno Antonny (CNRS, France)
"In vitro studies of the dynamics of the COPI and COPII coats" |
| Tommy Nilsson (EMBL, Heidelberg, Germany)
"New techniques to probe Golgi function" |
| Coffee Break |
| Nihal Altan-Bonnet (NIH, Bethesda, MD)
Short Talk: "Arf1 dynamics and its role in mitotic Golgi disassembly, chromosome segregation and cytokinesis" |
| Juan Bonifacino (NIH, Bethesda, MD)
"Molecular Recognition Events in Protein Coat Function" |
| Scotty Robinson (MBL, Cambridge, UK)
"Coated vesicle adaptors" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Protein Folding / Translocation / Turnover |
| Discussion Leader: Chris Akey (Boston Univ. Sch. Med., Boston, MA) |
| Jonathan Weissman (UCSF, San Francisco, CA)
"Mechanisms of Oxidative Protein Folding in the ER" |
| Ineke Braakman (Utrecht University, Utrecht, Holland)
Short Talk: "Protein folding and disulfide bond formation in the ER" |
| Tom Rapoport (Harvard Univ., Boston, MA)
"Transport of Proteins In and Out of the ER" |
| Art Johnson (Texas A&M)
"Regulation of ER membrane permeability by nascent chain folding inside the ribosome" |
| Randy Hampton (UCSD, La Jolla, CA)
"Quality and quantity control in the ER" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Vesicle Fission, Targeting and Fusion |
| Discussion Leader: Elizabeth Sztul (Univ. Alabama, Birmingham, AL) |
| William Wickner (Dartmouth University, Dartmouth, NH)
"Yeast Vacoule Fusion Mechanisms" |
| William Balch (Scripps Institute, La Jolla, CA)
"GTPase Regulation of Cargo Traffic" |
| Aki Nakano (RIKEN, Japan)
Short Talk: "Dynamic Organization of Yeast Golgi" |
| Coffee Break |
| Fred Hughson (Princeton University, Princeton, NJ)
"Toward Structure and Function of the Conserved Oligomeric Golgi (COG) Complex" |
| Peter Novick (Yale University, New Haven, CT)
"Spatial Regulation of the Secretory Machinery" |
| Susan Ferro-Novick (Yale University, New Haven, CT)
"Myo4p, a type V myosin motor, is required for ER inheritance in Saccharomyces cerevisiae" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Organelle Maintenance and Biogenesis |
| Discussion Leader: Kathryn Howell (Univ. Colorado HSC, Denver, CO) |
| Peter Walter (UCSF, San Francisco, CA)
"ER biogenesis" |
| Janet Shaw (University of Utah, Salt Lake City, UT)
"Mitochondrial Machinations: The Role of GTPases in Mitochondiral Membrane Fission and Fusion" |
| Carla Koehler (UCLA, Los Angeles, CA)
Short Talk: "Protein import into the mitochondrial inner membrane" |
| Stan Terlecky (Wayne State University)
Short Talk: "Peroxisome Senescence on Human Fibroblasts" |
| Graham Warren (Yale University, New Haven, CT)
"Biogenesis of the Golgi apparatus in protozoan parasites" |
| Ben Glick (University of Chicago, Chicago, IL)
"Building the Golgi" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Control of Signaling/Transport by Membrane Partitioning and Remodeling |
| Discussion Leader: Michael Roth (UTSW Medical Center, Dallas, TX) |
| Kai Simons (Max Planck Institute, Dresdan, Germany)
"O-glycans and Lipid Rafts in Cell Surface Transport in Yeast" |
| Marino Zerial (Max Planck Institute, Dresdan, Germany)
"Rab Domains in Endosome Organization and Signaling" |
| Vivek Malhotra (UCSD, La Jolla, CA)
"Regulating the Formation of Transport Vesicles and Entry into Mitosis from Golgi Membranes" |
| Coffee Break |
| Scott Emr (UCSD, La Jolla, CA)
"Lipid Kinase Signaling and Ubiquitin in Endosomal Trafficking" |
| Linda Hicke (Northwestern University, Chicago, IL)
"Phosphoinositides regulate ubiquitination of endosomal cargo by the Rsp5 ubiquitin ligase" |
| Mark Philips (New York University, NYC, NY)
Short Talk: "Compartment-Specific RAS Signaling" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Lipid, Cytoskeleton, and Membrane Interactions |
| Discussion Leader: Silvia Corvera (U. Mass., Worcester, MA) |
| 7:30 pm - 9:00 pm | Pietro De Camilli (Yale University, New Haven, CT)
"Phosphoinositides in the regulation of membrane traffic at the synapse" |
| 8:00 pm - 8:20 pm | John Hancock (University of Queensland, Brisbane, Australia)
Short Talk: "Plasma membrane micro-localization of Ras proteins" |
| 8:20 pm - 8:40 pm | John Hammer (NIH, Bethesda, MD)
"Molecular Genetic Analysis of Motor: Organelle Interactions" |
| 8:40 pm - 9:00 pm | Mark Stamnes (Univ. Iowa Coll Med, Iowa City, IA)
Short Talk: "Connecting COPI vesicles to the cytoskeleton" |
| 9:00 pm - 9:30 pm | Antonella De Matteis (Consorzio Negri Sud, Italy)
"The PI4P binding proteins FAPPs control the formation of transport carriers at the TGN" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Membrane Transport in Cell Motility and Development |
| Discussion Leader: Sharon Tooze (Imperial Cancer Res., London, UK) |
| Mark Bretscher (MBL, Cambridge University, Cambridge, UK)
"How Does an Amoeboid Cell Move?" |
| Ira Mellman (Yale University, New Haven, CT)
"Sorting and transporting cargo in polarized cells" |
| Enrique Rodrigues-Boulan (Cornell Univ. Med. College, NYC, NY)
"Live imaging of protein exit from the TGN in epithelial cells" |
| Coffee Break |
| Lois Weisman (Univ. Iowa, Iowa City, IA)
Short Talk: "Regulation of myosin V-based membrane movement" |
| Phil Beachy (Johns Hopkins University Medical School, Baltimore, MD)
"Lipids and transport in Hedgehog signaling" |
| Aaron Turkewitz (University of Chicago, Chicago, IL)
Short Talk: "The regulation of dense core formation in Tetrahymena secretory granules" |
| Sandy Simon (Rockefeller University, NYC, NY)
Short Talk: "Characterization of the steps in vesicle-membrane fusion" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Membrane Dynamics |
| Discussion Leader: Yoav Henis (Tel-Aviv Univ., Tel-Aviv, Israel) |
| Ken Jacobson (Univ. North Carolina, Chapel Hill, NC)
"Lipid Rafts: Function in Search of Structure" |
| Aki Kusumi (Univ. Nagoya, Japan)
"Single Molecule Observations in Stabilized Rafts Revealed by Digital Signal Transduction" |
| Anne Kenworthy (Vanderbilt University, TN)
Short Talk: "Dynamics of Lipid Rafts at the Cell Surface" |
| Wolf Almers (Oregon Health Science Univ., Portland, OR)
"Imaging the microphysiology of exocytosis and endocytosis by evanescent field microscopy" |
| Joshua Zimmerberg (NIH, Bethesda, MD)
Short Talk: "Is a Lipid Fence Formed by Raft Lipids and Influenza HA Needed for Membrane Fusion?" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
