| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Transport Carrier Formation |
| Discussion Leader: Randy Schekman (UC Berkeley) |
| 7:30 pm - 8:00 pm | Vivek Malhotra (UCSD)
Formation of transport carriers of the TGN to cell surface pathway |
| 8:00 pm - 8:30 pm | Bruno Antonny (Université de Nice)
How ArfGAP1 senses membrane curvature to control COPI dynamics |
| 8:30 pm - 8:45 pm | Todd Graham (Vanderbilt University)
Role for a lipid flippase in budding post-Golgi vesicles |
| 8:45 pm - 9:00 pm | Raul Rojas (NIH/NICHD)
Redundant functions of Snx1 and Snx2 in the recruitment of mammalian retromer to membranes and the trafficking of CI-MPR |
| 9:00 pm - 9:15 pm | Meir Aridor (University of Pittsburgh)
COPII vesicle formation and fission |
| 9:15 pm - 9:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Photo |
| 9:00 am - 12:30 pm | Organelle Biogenesis and Dynamics |
| Discussion Leader: Graham Warren (Yale University) |
| 9:00 am - 9:30 am | Judith Klumperman (Utrecht University Medical School)
Endosomal carriers involved in protein transport |
| 9:30 am - 10:00 am | Jennifer Lippincott-Schwartz (NIH/NICHD)
Golgi inheritance in mammalian cells depends on ER absorptive/export activities |
| 10:00 am - 10:15 am | Aki Nakano (Riken Discovery Research Institute)
Live imaging of yeast Golgi cisternal dynamics |
| 10:15 am - 10:30 am | Ben Glick (University of Chicago)
Golgi formation and dynamics |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Sean Munro (MRC, Cambridge)
Arf-like GTPases and membrane traffic in the Golgi |
| 11:30 am - 12:00 pm | Alberto Luini (Consorzio Mario Negri Institute)
A Golgi-based signaling circuit coordinates the secretory pathway |
| 12:00 pm - 12:15 pm | Cynthia He (Yale University School of Medicine)
Golgi duplication in Trypanosoma brucei requires centrin2 |
| 12:15 pm - 12:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Lipids and Compartment Identity |
| Discussion Leader: Pietro DeCamilli (Yale University) |
| 7:30 pm - 8:00 pm | Temo Kurzchalia (Max Planck Institute, Dresden)
Many faces of cholesterol: From membrane structure to signaling |
| 8:00 pm - 8:30 pm | Jean Gruenberg (University of Geneva)
Dynamics of intra-endosomal membranes |
| 8:30 pm - 9:00 pm | Scott Emr (UCSD)
PIPs point the way |
| 9:00 pm - 9:15 pm | Peter Mayinger (Oregon Health and Science University)
Growth-dependent phosphoinositide control at ER and Golgi |
| 9:15 pm - 9:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Conformational Dynamics at the Membrane |
| Discussion Leader: Bill Balch (Scripps Research Institute) |
| 9:00 am - 9:30 am | Ehud Isacoff (UC Berkeley)
Conformational dynamics of a voltage-gated ion channel |
| 9:30 am - 10:00 am | Diane Papazian (UCLA)
Voltage-induced conformational changes in ion channels |
| 10:00 am - 10:15 am | Christopher Reyes (Scripps Research Institute)
Structural basis of lipopolysaccharide flipping: ABC transporter MsbA in complex with ADP·Vi and lipopolysaccharide |
| 10:15 am - 10:30 am | Fred van Goor (Vertex Pharmaceuticals)
Small molecule modulators of DF508-CFTR in HBE isolated from multiple CF patients |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Don Engelman (Yale University)
Transmembrane helix insertion can transport molecules into cells |
| 11:30 am - 12:00 pm | David Andrews (McMaster University)
Bcl-2 protein gymnastics regulate the permeabilization of mitochondria during apoptosis |
| 12:00 pm - 12:15 pm | Gia Voeltz (Harvard Medical School)
A role for reticulon/nogo in the formation of the tubular endoplasmic reticulum |
| 12:15 pm - 12:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Membrane Fusion |
| Discussion Leader: Bill Wickner (Dartmouth Medical School) |
| 7:30 pm - 8:00 pm | Margaret Kielian (Albert Einstein College of Medicine)
Alphavirus-membrane fusion: Structural and functional studies of a class II fusion protein |
| 8:00 pm - 8:30 pm | Reinhart Jahn (Max Planck Inst Biophys Chem, Gottingen)
Molecular anatomy of a trafficking organelle |
| 8:30 pm - 9:00 pm | Ed Chapman (University of Wisconsin-Madison)
Mechanisms and modes of exocytosis |
| 9:00 pm - 9:15 pm | Rutilio Fratti (Dartmouth Medical School)
Regulatory lipids and fusion proteins cooperate to form a ring shaped microdomain for vacuole hemifusion and fusion |
| 9:15 pm - 9:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Organizing Membrane Subdomains |
| Discussion Leader: Ira Mellman (Yale University) |
| 9:00 am - 9:30 am | Matthias Weiss (DKFZ)
Domain formation in ER and Golgi: An in silico approach |
| 9:30 am - 10:00 am | Catherine Rabouille (University Medical Center Utrecht)
The organization and function of the tER-Golgi units in Drosophila |
| 10:00 am - 10:15 am | Adam Linstedt (Carnegie Mellon University)
Uniform Golgi enzyme distribution in mammalian cells requires lateral cisternal fusion |
| 10:15 am - 10:30 am | Tobias Walther (UCSF)
Eisosomes: A static cortical protein assembly that defines sites of endocytosis |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Rob Parton (University of Queensland)
New ultrastructural insights into clathrin-independent endocytic pathways |
| 11:30 am - 12:00 pm | Mark Metzstein (Stanford University)
Role of vesicle trafficking in the formation of intracellular lumens in Drosophila tracheal terminal cells |
| 12:00 pm - 12:15 pm | Greg Odorizzi (University of Colorado)
Distinct sizes of MVB vesicles revealed by electron tomography |
| 12:15 pm - 12:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Membrane Bending/Fission |
| Discussion Leader: Janet Shaw (University of Utah) |
| 7:30 pm - 8:00 pm | Harvey McMahon (MRC, Cambridge)
The hare and the tortoise: Different mechanisms of synaptic vesicle endocytosis |
| 8:00 pm - 8:30 pm | Michael Kozlov (Tel Aviv University)
Elastic consideration of membrane fission |
| 8:30 pm - 9:00 pm | Jodi Nunnari (UC Davis)
Dnm1 is the master regulator of mitrochondrial fission |
| 9:00 pm - 9:15 pm | Toshiki Itoh (Yale University)
A family of actin regulatory proteins defined by the presence of a BAR-like membrane deforming module |
| 9:15 pm - 9:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Diverse Translocation Machineries |
| Discussion Leader: Tom Rapoport (Harvard Medical School) |
| 9:00 am - 9:30 am | Art Johnson (Texas A&M University)
Mechanism of BiP-mediated gating of the aqueous ER translocon pore |
| 9:30 am - 10:00 am | Shou-ou Shan (Calif Institute of Technology)
A tale of two GTPases in co-translational protein targeting |
| 10:00 am - 10:30 am | Hidde Ploegh (Harvard Medical School)
Surprises in the dislocation of type I membrane proteins from the endoplasmic reticulum: New components identified |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Nikolaus Pfanner (Universität Freiburg)
Import and assembly of mitochondrial proteins |
| 11:30 am - 12:00 pm | Andrei Fagarasanu (University Alberta)
Peroxisome dynamics in Saccharomyces cerevisiae |
| 12:00 pm - 12:15 pm | Henk Tabak (Utrecht University)
A new function of the ER: Formation of peroxisomes |
| 12:15 pm - 12:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Sorting and Targeting |
| Discussion Leader: Peter Walter (UCSF) |
| 7:30 pm - 7:45 pm | Scott M. Stagg (Scripps Research Institute)
Structure of the self-assembling molecular lattice mediating COPII vesicle budding |
| 7:45 pm - 8:00 pm | Bob Fuller (University of Michigan)
Direct recognition by GGA proteins of distinct types of sorting signals in TGN-endosome transport |
| 8:00 pm - 8:30 pm | Linda Hicke (Northwestern University)
Role of ubiquitin-binding proteins in receptor endocytosis |
| 8:30 pm - 8:45 pm | Ramanujan Hegde (NIH)
A mechanism for preemptive quality control at the endoplasmic reticulum |
| 8:45 pm - 9:00 pm | Ruth Collins (Cornell University)
Rab GTPase activation and the mystery of familial dysautonomia |
| 9:00 pm - 9:15 pm | Suzanne Pfeffer (Stanford University)
A TGN tether for Mannose 6-phosphate receptor recycling |
| 9:15 pm - 9:30 pm | Chair's overview and chair led discussion on unresolved issues and future directions |
| 2005 Gordie Awards |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
