| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | MEMBRANE DOMAINS |
| Discussion Leader: Scott Emr (Cornell University) |
| 7:40 pm - 8:05 pm | Bill Wickner (Dartmouth University)
"Yeast vacuole fusion: Lipids, Rab, HOPS, and SNAREs, dancing in a ring" |
| 8:05 pm - 8:30 pm | David Stephens (University of Bristol)
"Organization and mechanism of COPII dependent budding from the mammalian ER" |
| 8:30 pm - 8:55 pm | Suzanne Pfeffer (Stanford University)
"GTPase control of tethers and SNAREs that distinguish recycling routes to the TGN" |
| 8:55 pm - 9:10 pm | Richa Rikhy (NIH)
"Analysis of dynamin's function in the developing syncytial Drosophila embryo" |
| 9:10 pm - 9:30 pm | Chair's Overview and Open Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | MEMBRANE FUSION |
| Discussion Leader: Hugh Pelham (MRC Laboratory of Molecular Biology) |
| 9:00 am - 9:25 am | Josep Rizo (UT Southwestern Medical Center)
"How can proteins bend membranes to induce neurotransmitter release?" |
| 9:25 am - 9:50 am | James McNew (Rice University)
"Regulation of SNARE-mediated membrane fusion" |
| 9:50 am - 10:05 am | Yeon-Kyun Shin (Iowa State University)
"A single molecule view on synaptic membrane fusion" |
| 10:05 am - 10:30 am | Coffee Break |
| 10:30 am - 10:45 am | Doug Hattendorf (Stanford University)
"Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism" |
| 10:45 am - 11:10 am | Reinhard Jahn (Max-Planck-Institute for Biophysical Chemistry)
"Exocytosis - attempts to bridge the gap between native and artificial membranes" |
| 11:10 am - 11:35 am | Andreas Mayer (University of Lausanne)
"The docking event in yeast vacuole fusion" |
| 11:35 am - 11:50 am | Christian Ungermann (University of Osnabrueck)
"Function of tethering complexes in endolysosomal biogenesis and cargo sorting" |
| 11:50 am - 12:05 pm | Michael Sacher (Concordia University)
"A structure-based approach to understanding the function of a vesicle tethering complex" |
| 12:05 pm - 12:30 pm | Chair's Overview and Open Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | LIPID TRANSPORT AND LOCALIZATION |
| Discussion Leader: Fred Maxfield (Weill Cornell Medical College) |
| 7:30 pm - 7:55 pm | Dawn Brasaemle (Rutgers Cook College)
"Lipid droplet-associated proteins and the control of triacylglycerol metabolism" |
| 7:55 pm - 8:20 pm | Will Prinz (NIH)
"Oxysterol-binding proteins and non-vesicular sterol transport" |
| 8:20 pm - 8:45 pm | Peter Espenshade (Johns Hopkins University)
"Sterol sensing and adaptation to hypoxia" |
| 8:45 pm - 9:00 pm | Arun Radhakrishnan (University of Texas Southwestern Medical Center)
"Protein sensors for membrane sterols" |
| 9:00 pm - 9:30 pm | Chair's Overview and Open Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ORGANELLE STRUCTURE AND DYNAMICS |
| Discussion Leader: Lois Weisman (University of Michigan) |
| 9:00 am - 9:25 am | Janet Shaw (University of Utah)
"The road to Budsville: multiple pathways for mitochondrial inheritance in yeast" |
| 9:25 am - 9:50 am | Liza Pon (Columbia University)
"Mitochondrial motility and inheritance in budding yeast: checks and balances" |
| 9:50 am - 10:05 am | Yui Jin (University of Michigan)
"PTC1 regulates the myosin V-based inheritance of several organelles via action on both myosin V and its receptors" |
| 10:05 am - 10:30 am | Coffee Break |
| 10:30 am - 10:45 am | Shawn Ferguson (Yale University School of Medicine)
"The role of dynamins in synaptic vesicle endocytosis" |
| 10:45 am - 11:10 am | Chris Kaiser (MIT)
"Redox homeostasis of the endoplasmic reticulum" |
| 11:10 am - 11:35 am | Catherine Rabouille (University of Utrecht)
"Novel role for dGRASP in fly development" |
| 11:35 am - 11:50 am | Suraj Saksena (Cornell University)
"MVB pathway: the assembly and disassembly of ESCRT-III" |
| 11:50 am - 12:05 pm | Roger Williams (MRC Laboratory of Molecular Biology)
"Sorting out and shaping up in the MVB pathway" |
| 12:05 pm - 12:30 pm | Chair's Overview and Open Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PATHOGENS AND MEMBRANE TRAFFIC |
| Discussion Leader: Pascale Cossart (Pasteur Institute) |
| 7:30 pm - 7:55 pm | Norma Andrews (Yale University)
"Plasma membrane repair in cells permeabilized by bacterial toxins" |
| 7:55 pm - 8:20 pm | Craig Roy (Yale University)
"Bacterial proteins that control Rab1 recruitment, activation and conversion on the Legionella-containing vacuole" |
| 8:20 pm - 8:45 pm | Tom Wileman (Pirbright Laboratory)
"Response of early secretory compartments, aggresomes and autophagosomes to virus infection" |
| 8:45 pm - 9:00 pm | Stephen Gould (Johns Hopkins University)
"Higher-order oligomerization targets plasma membrane proteins, including HIV Gag, to exosomes" |
| 9:00 pm - 9:30 pm | Chair's Overview and Open Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | VESICLE FORMATION |
| Discussion Leader: Sandy Schmid (The Scripps Research Institute) |
| 9:00 am - 9:25 am | Bill Balch (The Scripps Research Institute)
"The adaptability of trafficking" |
| 9:25 am - 9:50 am | Anne Spang (Biozentrum, University of Basel)
"Analysis of the role of ArfGAPs in vesicle formation" |
| 9:50 am - 10:05 am | Rajesh Ramachandran (The Scripps Research Institute)
"Real-time observation of dynamin reveals a dynamic interaction with the membrane under various nucleotide- and effector-bound states" |
| 10:05 am - 10:30 am | Coffee Break |
| 10:30 am - 10:45 am | Ela Knapik (Vanderbilt University)
"Genetic analysis of collagen trafficking in developing zebrafish chondrocytes" |
| 10:45 am - 11:10 am | Randy Schekman (University of California at Berkeley)
"An E. coli type III secretion protein required for pathogenesis that interferes with host secretion and COPII function" |
| 11:10 am - 11:35 am | Charlie Barlowe (Dartmouth University)
"COPII-dependent ER export mechanisms" |
| 11:35 am - 11:50 am | Karin Reinisch (Yale University School of Medicine)
"A catalytic coiled-coil: activation of the Rab GTPase Sec4p by Sec2p" |
| 11:50 am - 12:05 pm | Mary Munson (UMass Medical School)
"Molecular dissection of the exocyst complex" |
| 12:05 pm - 12:30 pm | Chair's Overview and Open Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | REACHING THE PLASMA MEMBRANE |
| Discussion Leader: Peter Novick (Yale University) |
| 7:30 pm - 7:55 pm | Vivek Malhotra (University of California at San Diego)
"Formation of transport carriers at the trans-Golgi network" |
| 7:55 pm - 8:20 pm | Patrick Brennwald (University of North Carolina at Chapel Hill)
"Role of the Lgl/Sro7 protein family in polarized exocytosis" |
| 8:20 pm - 8:45 pm | Ira Mellman (Yale University)
"Formation of polarized plasma membrane domains in epithelial cells" |
| 8:45 pm - 9:00 pm | Heike Folsch (Northwestern University)
"Molecular basis for AP-1B function in polarized membrane trafficking" |
| 9:00 pm - 9:30 pm | Chair's Overview and Open Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TRAVERSING THE GOLGI |
| Discussion Leader: Alberto Luini (Consorzio Mario Negri Sud) |
| 9:00 am - 9:25 am | Adam Linstedt (Carnegie Mellon University)
"Golgi compartmentalization requires coat-tether interaction" |
| 9:25 am - 9:50 am | Francis Barr (Max-Planck-Institute of Biochemistry)
"Polarized trafficking to cilia" |
| 9:50 am - 10:05 am | Vladimir Lupashin (University of Arkansas for Medical Sciences)
"The COG complex directly interacts with the t-SNARE Syntaxin5a/Sed5 to enhance stability of the intra-Golgi SNARE complex" |
| 10:05 am - 10:30 am | Coffee Break |
| 10:30 am - 10:45 am | David Banfield (Hong Kong University of Science and Technology)
"A signal-mediated mechanism for the retention of glycosyltransferases in the yeast Golgi" |
| 10:45 am - 11:10 am | Roman Polishchuk (Consorzio Mario Negri Sud)
"Soluble proteins traverse the Golgi by diffusion via cPLA2a-dependent intercisternal continuities" |
| 11:10 am - 11:35 am | Aki Nakano (RIKEN Discovery Research Institute)
"State-of-the-art imaging of the secretory pathway: from the ER and through the Golgi" |
| 11:35 am - 11:50 am | Nava Segev (University of Illinois at Chicago)
"Ypt/Rab GTPases and traffic coordination" |
| 11:50 am - 12:05 pm | Cecilia Alvarez (Universidad Nacional de Cordoba)
"Role of Rab1b in ER to Golgi transport" |
| 12:05 pm - 12:30 pm | Chair's Overview and Open Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | ENTERING THE ER |
| Discussion Leader: Ari Helenius (Swiss Federal Institute of Technology) |
| 7:30 pm - 7:55 pm | Tom Rapoport (Harvard Medical School)
"ER translocon structure and function" |
| 7:55 pm - 8:20 pm | Gunnar von Heijne (Stockholm University)
"Sec61-mediated insertion of membrane proteins in the ER" |
| 8:20 pm - 8:45 pm | Peter Walter (University of California at San Francisco)
"Making life/death decisions with the unfolded protein response" |
| 8:45 pm - 9:00 pm | Federica Brandizzi (Michigan State University)
"Dynamics of the ER export sites in plant cells" |
| 9:00 pm - 9:20 pm | Chair's Overview and Open Discussion |
| 9:20 pm | 2007 Gordie Awards |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
