SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:00 pm | At the Frontier in Molecular Membrane Biology |
| Discussion Leader: Charlie Barlowe (Dartmouth) |
7:45 pm - 8:35 pm | Peter Walter (University of California San Francisco)
"The unfolded protein response in health and disease" |
8:35 pm - 9:00 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Membrane Bending and Fusion |
| Discussion Leader: Jodi Nunnari (University of California Davis) |
9:00 am - 9:20 am | Tom Rapoport (Harvard Medical School)
"How the ER gets into shape" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | James McNew (Rice University)
"Molecular analysis of membrane fusion by the GTPase atlastin" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Marijn Ford (University of California Davis)
"Molecular mechanisms of mitochondrial behavior" |
10:20 am -10:30 am | Discussion |
10:30 am | Group Photo / Coffee Break |
11:00 am - 11:20 am | Sandy Schmid (Scripps Research Institute)
"A tale of two dynamins" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Bill Wickner (Dartmouth)
"Protein:lipid interplay for membrane fusion" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Daniel Kuemmel (Yale University)
"Structural basis for clamping of membrane fusion by complexin" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Wei Guo (University of Pennsylvania)
"Membrane remodeling by the exocyst component Exo70" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Membrane Coats |
| Discussion Leader: Sandy Schmid (Scripps Research Institute) |
7:30 pm - 7:50 pm | David Owen (University of Cambridge)
"Selecting cargo for clathrin mediated endocytosis" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Randy Schekman (University of California Berkeley)
"Accommodation of large cargo by the COPII coat" |
8:20 pm - 8:30pm | Discussion |
8:30 pm - 8:40 pm | Jeroen Strating (Heidelberg University)
"Functional studies of coatomer using recombinant coatomer subcomplexes" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:05 pm | Max Nachury (Stanford University)
"Trafficking of signaling receptors to and from the primary cilium" |
9:05 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Dusanka Deretic (University of New Mexico)
"Mechanism for coupling of cargo recognition with cargo destination in delivery to the primary cilium" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ER in Health and Disease |
| Discussion Leader: Randy Schekman (University of California Berkeley) |
9:00 am - 9:20 am | Bob Keenan (University of Chicago)
"Tail-anchored membrane protein biosynthesis" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Ineke Braakman (University of Utrecht)
"Protein folding in the Endoplasmic Reticulum" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Liz Miller (Columbia University)
"High throughput yeast genetics reveals novel aspects of ER quality control" |
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Sima Lev (Weizmann Institute)
"The Conserved Oligomeric Golgi (COG) complex and its role in retrograde trafficking" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Aki Nakano (RIKEN)
"High-resolution live imaging of cargo delivery from ER exit sites to the Golgi apparatus" |
11:40 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Jon Audhya (University of Wisconsin)
"Regulation of COPII recruitment at ER exit sites" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Bill Balch (Scripps Research Institute)
"Trafficking, vesicles and proteostasis" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Leading Edges of Membrane Biology I |
| Discussion Leader: Suzanne Pfeffer (Stanford University) |
7:30 pm - 7:50 pm | Jay Groves (University of California Berkeley)
"Spatial organization and the mechanics of signal transduction in cell membranes" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:10 pm | Jeanne Stachowiak (Sandia National Laboratories)
"Epsin1 bends lipid membranes by molecular crowding" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:25 pm | Usha Acharya (University of Massachusetts Medical School)
"Sphingolipids regulate intracellular trafficking to maintain photoreceptor homeostasis" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Fred Hughson (Princeton University)
"CATCHR-family complexes: structure and mechanism" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Susan Ferro-Novick (University of California San Diego)
"Coats, tethers, Rabs and SNAREs work together to mediate the specificity of vesicle traffic" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Organelle Structure and Function |
| Discussion Leader: Fred Hughson (Princeton University) |
9:00 am - 9:20 am | Janet Shaw (University of Utah)
"Mechanisms of mitochondrial membrane dynamics" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Gia Voeltz (University of Colorado)
"A 3D analysis of yeast ER structure reveals how ER Domains are organized by membrane curvature" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Federica Brandizzi (Michigan State University)
"Integrity of the plant Golgi" |
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Graham Warren (University of Vienna)
"Biogenesis of the Golgi" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Greg Lavieu (Yale University)
"Real-time imaging of inter-Golgi transport supports a bi-directional vesicular transport model" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:05 pm | Anne Spang (University of Basel)
"Novel roles for the ArfGEFs in C. elegans" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Maya Schuldiner (Weizmann Institute)
"Towards creation of a traffickome: a novel approach to pair secretory cargo receptors with their cargo" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Leading Edges of Membrane Biology II |
| Discussion Leader: Peter Novick (University of California San Diego) |
7:30 pm - 7:50 pm | Jonathan Weissman (University of California San Francisco)
"Towards a comprehensive view of the mammalian endocytic machinery" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Amy Kiger (University of California San Diego)
"Coordination of phosphoinositide and Rab GTPase regulation and functions" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Suzanne Pfeffer (Stanford University)
"Transport vesicle tethering at the TGN" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Svetlana Dokudovskaya (IGR-Villejuif)
"A novel conserved coatomer-related complex" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Jodi Nunnari (University of California Davis)
"MitOS is a conserved mitochondrial skeletal structure" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Endosomes and Autophagy |
| Discussion Leader: Beverly Wendland (Johns Hopkins University) |
9:00 am - 9:20 am | Jennifer Lippincott-Schwartz (National Institutes of Health - NICHD)
"Anatomy of cytokinetic membrane abscission by ESCRTs" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Scott Emr (Cornell University)
"TORC1 regulates endocytosis via a kinase signaling cascade and phosphoinhibition of a Ub ligase adaptor" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | James Hurley (National Institutes of Health - NIDDK)
"New ways for ESCRTs to get to endosomes" |
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Tamotsu Yoshimori (Osaka University)
"Autophagosome Formation: between the ER and Mitochondria" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Liz Conibear (University of British Columbia)
"New regulators of the AP-1 complex" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Peter Van Der Sluijs (University Medical Center Utrecht)
"Munc13-4 rab27 complex is required for tethering secretory lysosomes at the plasma membrane" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Heike Folsch (Northwestern University)
"Regulation of AP-1B function in polarized epithelial cells" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Small GTPases in Membrane Dynamics |
| Discussion Leader: Francis Barr (University of Oxford) |
7:30 pm - 7:50 pm | Rodger Goody (Max-Planck-Dortmund)
"Learning about vesicular transport from bacteria" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:10 pm | Chris Fromme (Cornell University)
"Regulation of Arf GTPase activation and effector function at the trans-Golgi network" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:35 pm | Barth Grant (Rutgers University)
"Basolateral recycling in a C. elegans polarized epithelium: RAB-10 and its effectors" |
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 8:55 pm | Stefan Eimer (ENI-Gottingen) "Regulation of RAB-2 GTPase involved in dense-core vesicle maturation" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Peter Novick (University of California San Diego)
"Regulation of membrane traffic by networks of Rab GTPases" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |