SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Pioneering the frontiers of membrane biology |
| Discussion Leader: Francis Barr (Oxford, UK) |
7:40 pm - 8:10 pm | Felix Wieland (Biochemie Zentrum, Heidelberg)
"Vesicle formation: mechanisms of coating and fission"
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8:10 pm - 8:30 pm | Discussion |
8:30 pm - 9:15 pm | James Rothman (Yale)
"Regulation of Membrane Fusion for Synchronous Neurotransmitter Release" |
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of protein translocation and biosynthesis |
| Discussion Leader: Karin Reinisch (Yale) |
9:00 am - 9:20 am | Tom Rappoport (Harvard)
"Mechanisms of protein translocation across membranes"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Irmi Sinning (Biochemie-Zentrum, Heidelberg)
"SIMIBI twins regulate protein translocation"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Shu-Ou Shan (Caltech)
"ATPase and GTPase tangos during intracellular protein targeting"
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10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Ramanujan Hegde (MRC-LMB Cambridge, UK)
"Quality control of errors during protein biosynthesis"
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11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Maya Schuldiner (Weizman Institute, Israel)
"The SND pathway - a new and conserved pathway for targeting SRP Independent proteins to the ER"
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11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Maho Niwa (UCSD) |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cytoskeleton-membrane interactions |
| Discussion Leader: Suzanne Pfeffer (Stanford) |
7:30 pm - 7:50 pm | Melina Schuh (MRC-LMB Cambridge, UK)
"Vesicles as actin network modulators"
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7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Michael Way (CRUK-LRI, London, UK)
"How clathrin promotes actin dependent spread of vaccinia"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Elizabeth Chen (Johns-Hopkins University School of Medicine)
"Mechanisms of cell-cell fusion"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Anna Akhmanova (Utrecht, The Netherlands)
"Control of microtubule-membrane interactions by microtubule end-binding proteins"
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9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Vesicle formation and cargo selection |
| Discussion Leader: Maya Schuldiner (Weizman Institute, Israel) |
9:00 am - 9:20 am | Vivek Malhotra (CRG Barcelona, Spain)
"Getting Collagen out of the ER"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Liz Miller (Columbia)
"It takes two: Erv14 and Sec24 cooperate to promote ER export of plasma membrane proteins"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Charles Barlowe (Dartmouth)
"Coordination of COPII-dependent export and ER quality control"
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10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Lauren Jackson (Cambridge, UK)
"Molecular basis for recognition of dilysine-based cargo by the COPI coat" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Susan Ferro-Novick (UCSD)
"The role of phosphorylation and dephosphorylation in COPII vesicle traffic"
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11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Jon Audhya (University of Wisconsin-Madison)
"Regulatory mechanisms that control COPII-mediated vesicle secretion"
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12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Organelle biogenesis and structure |
| Discussion Leader: Anne Spang (Biozentrum, Basel) |
7:30 pm - 7:50 pm | Eija Jokitalo (University of Helsinki, Finland)
"Interplay between ER sheets and actin cytoskeleton" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Tobias Walther (Yale)
"Lipid Droplet biogenesis from the Endoplasmic Reticulum"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Gia Voeltz (Boulder)
"New roles for ER structure and dynamics at inter-organelle contact sites"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Mikael Simons (Göttingen, Germany)
"Mechanisms of myelin membrane assembly and wrapping in the central nervous system"
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9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms for coding membrane identity |
| Discussion Leader: Gia Voeltz (Boulder) |
9:00 am - 9:20 am | Christian Ungermann (Osnabrück, Germany)
"GAP and GEF-control of yeast Rab5 and Rab7 proteins"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Shaeri Mukherjee (Yale)
"Manipulation of Rab GTPases by Legionella effectors"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Suzanne Pfeffer (Stanford)
"Tethering at the Golgi by Golgins and motor proteins"
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10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Sean Munro (MRC-LMB, Cambridge, UK)
"Small G proteins and Golgi membrane identity"
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11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Aymelt Itzen (Munich, Germany)
"RabGEFs are a major determinant for specific Rab membrane targeting"
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11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Karen Reinisch (Yale)
"About the architecture of the Stt4 PI4P kinase patch"
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12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Structural insights into membrane shaping and bending |
| Discussion Leader: Fred Hughson (Princeton) |
7:30 pm - 7:50 pm | Vincenz Unger (Northwestern)
"Bending Boundaries - A Tale About Molecular Mechanisms of Membrane Remodeling"
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7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | James Hurley (UC Berkeley)
"The beginning of the end: How the Atg1 complex scaffolds autophagosome biogenesis"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Patricia Bassereau (Institut Curie, Paris, France)
"Membrane bending induced by transmembrane proteins"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Mike Henne (Cornell)
"Oligomerization and membrane insertion drive ESCRT-III-mediated vesicle budding at multivesicular bodies"
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9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Golgi and post-Golgi trafficking |
| Discussion Leader: Sean Munro (MRC-LMB Cambridge, UK) |
9:00 am - 9:20 am | Julia von Blume (MPI of Biochemistry, Germany)
"Mechanism of secretory cargo sorting at the TGN"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Catherine Rabouille (Utrecht, The Netherlands)
"Secretion under stress and in pathology" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Anne Spang (Biozentrum Basel, Switzerland)
"Temporal and spatial control of the localization of plasma membrane proteins"
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10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:20 am | Ben Glick (Chicago)
"Role of Arf and COPI in yeast Golgi structure and dynamics"
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11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Peter Novick (UCSD)
"The Synaptobrevin Homolog, Snc2p Recruits the Exocyst to Secretory Vesicles by Binding to Sec6p" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Axel Brunger (Stanford)
"Reconstitution of calcium-triggered synaptic vesicle fusion"
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12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Trafficking in cell polarization and division |
| Discussion Leader: Anna Akhmanova (Utrecht, The Netherlands) |
7:30 pm - 7:50 pm | Randy Schekman (Berkeley)
"Sorting of planar cell polarity signaling receptors at the TGN"
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7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Sally Horne-Badovinac (Chicago)
"Spinning the matrix: polarized basement membrane secretion during organ morphogenesis"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Fernando Martin-Belmonte (CBMSO (CSIC), Madrid, Spain)
"PLLP controls single-hole formation in epithelial tubulogenesis"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Arnaud Echard (Institut Pasteur, Paris, France)
"Rab35 and PI(4,5)P2 homeostasis on membranes"
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9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |