Session I
Sunday PM, February 14 | G protein-coupled receptors |
- 6:00 pm - Welcome reception
- 7:30 pm - Introduction by Brian Kobilka, M.D.
- 7:40 pm - Henry R. Bourne, MD - "How do receptors talk to G proteins?"
- 8:20 pm - Thue W. Schwartz, MD, Ph.D. - "In vivo drug development - molecular pharmacology of virally encoded chemokines and chemokine 7TM receptors"
- 9:00 pm - Jurgen Wess, Ph.D. - "Structure-function analysis of G protein-coupled receptors"
Session II
Monday AM, February 15 | G Protein-coupled receptors |
- 9:00 am - Introduction by Agnes Schonbrunn, Ph.D.
- 9:10 am - T. Kendall Harden, Ph.D. - "G protein-coupled receptors for extracellular adenine and uridine nucleotides"
- 9:50 am - Elaine Sanders-Bush, Ph.D. - "Regulation of the serotonin 5-HT2C receptor by RNA editing"
- 10:30 am - Coffee / Photo break
- 11:20 am - Jerold J.M. Chun, M.D., Ph.D. - "Insights on lysophospholipid (LP) receptor signaling from analyses of the mammalian nervous system"
- 12:00 pm - Lunch
Session III
Monday PM, February 15 | Receptor Trafficking |
- 7:30 pm - Introduction by M. Marlene Hosey, Ph.D.
- 7:40 pm - Jeffrey Benovic, Ph.D. - "Role of GRKs and arrestins in receptor trafficking"
- 8:20 pm - Shaun Coughlin, M.D., Ph.D. - "Protease-activated receptor signaling and trafficking"
- 9:00 pm - Mark von Zastrow, M.D., Ph.D. - "Agonist-specific endocytosis of opioid receptors"
Session IV
Tuesday AM, February 16 | Heterotrimeric G proteins and RGS function |
- 9:00 am - Introduction by Eva Neer, M.D.
- 9:10 am - Melvin I. Simon, Ph.D. - "Galphaq and Galpha12 family knockouts"
- 9:50 am - David P. Siderovski, Ph.D. - "RGS11 & RGS12: Novel binding domains within the G-protein alpha GAPs"
- 10:25 am - Coffee break
- 10:55 am - Paul C. Sternweis, Ph.D. - "G-protein/Rho connections and regulation of phospholipase D"
- 11:30 am - Selected short talks
- Moritz Bünemann
- Richard Premont
- Ji-Yun Kim
- Vladen Slepak
- Thomas M. Wilkie
- 12:30 pm - Lunch
Session V
Tuesday PM, February 16 | Subcellular Localization of Signaling Molecules |
- 7:30 pm - Introduction by Lee Limbird, Ph.D.
- 7:40 pm - Dr. Michael P. Lisanti - "Caveolae, signaling and cell transformation"
- 8:20 pm - Daria Mochly-Rosen, Ph.D. - "Protein kinase C isozymes and their anchoring proteins; a pharmacological opportunity"
- 9:00 pm - Selected short talks
- Jeremy Richman
- Neil Fraser
- James Konopka
- Peter Devreotes
- Andrew Brown
Session VI
Wednesday AM, February 17 | Small G proteins, growth and cytoskeleton development |
- 9:00 am - Introduction by Joan Heller Brown, Ph.D.
- 9:10 am - Diane Barber, Ph.D. - "Role of Na-H exchangers in cytoskeletal organization"
- 9:50 am - J. Silvio Gutkind, Ph.D. - "Cell growth regulation by G protein-coupled receptors: From signal transduction to signal integration"
- 10:25 am - Coffee break
- 10:40 am - Dr. Kozo Kaibuchi - "Regulation of cytoskeleton and cell adhesion by targets of Rho family GTPases"
- 11:20 am - Dr. Jeffrey Settleman - "Regulation and function of Rho GTPases in development"
- 12:00 pm - Lunch
- Afternoon trip to Getty Museum (extra cost)
Session VII
Wednesday PM, February 17 | Keynote Speaker |
- 6:30 pm - Roger Tsien, Ph.D., ASPET Molecular Pharmacology Division Lecturer - "Glowing molecules as biological spies, industrial workhorses, and fun toys"
- 7:30 pm - Banquet
- 9:00 pm - Entertainment
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