SATURDAY |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Lecture |
3:45 pm - 4:15 pm | Brian Kobilka (Stanford University) |
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Structural biology of GPCRs and post-receptor components |
| Discussion Leaders: Susanna Cotecchia (University of Lausanne, Switzerland) and Philip E. Boulais (University of Sherbrooke, Canada) |
7:30 pm - 7:50 pm | Cheng Zhang (Stanford University) "Crystal structure of beta2 adrenergic receptor bound with an irreversible agonist" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Jacek Mokrosinski (University of Copenhagen, Denmark) "Highly conserved proline residues in TM-II and IV - importance for biased signaling probed in multiple 7TM receptors" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Jonathan Fay (Oregon Health and Science University) "Purification and Site-Directed Fluorescence Labeling Studies in the Human Neuronal Cannabinoid (CB1) Receptor" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Angeline M Lyon (Life Sciences Institute, University of Michigan) "Regulation and Activation of Phospholipase Cβ" |
9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Cell biology of GPCRs and post-receptor components |
| Discussion Leaders: JoAnn Trejo (University of California at San Diego) and James N Hislop (University of California at San Francisco) |
9:00 am - 9:20 am | Allen P Liu (The Scripps Research Institute) "Biophysical and chemical tools for studying GPCR endocytosis in living cells" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Frederic Jean-Alphonse (Imperial College, UK) "Spatio-temporal signaling regulation of gonadotropin receptors by GIPC and APPL1" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Anastasia G Henry (University of California at San Francisco) "Controlling GPCR endocytosis by ubiquitin-dependent regulation of clathrin-coated pit surface lifetime" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | General Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 3:00 pm | Physiological roles of GPCRs |
| Discussion Leader: Mark von Zastrow (University of California at San Francisco) and Claudia Staubert (University of Leipzig) |
1:30 pm - 1:50 pm | Dawn Thompson (Gallo Institute, University of California at San Francisco) "GASP and the postendocytic sorting of the Dopamine receptor family" |
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Cristina M Costantino (Mount Sinai School of Medicine, NY) "Agonism of cannabinoid receptor 2 attenuates HIV-1 infection in CD4+ T cells" |
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |