Saturday |
2:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Keynote Session: Signaling Mechanisms in Skeletal Muscle |
| Discussion Leader: Carlo Manno (Rush University, USA) |
3:45 pm - 4:20 pm | Martin Schneider (University of Maryland School of Medicine, USA) "Signaling Mechanisms in Skeletal Muscle" |
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | New Frontiers in
Excitation-Contraction Coupling and Its Modulation |
| Discussion Leader: Roger Bannister (University of Colorado, Denver, USA) |
7:30 pm - 7:50 pm | Michael Yuchi (University of British Columbia, Canada) "Crystal Structures of Repeat Domains in Ryanodine Receptors" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Anamika Dayal (Innsbruck Medical University, Austria) "The DHPR Calcium Current in Mammalian Skeletal Muscle: Just Vestigial?" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Ye Win Oo (The University of Newcastle, Australia) "Essential Role of Calmodulin in Dantrolene Inhibition of Cardiac and Skeletal RyRs" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Lan Wei-LaPierre (University of Rochester Medical Center, USA) "Reduced Intracellular Ca2+ Transients, Mitochondrial Ca2+ Uptake and Superoxide Production in Skeletal Muscle-Specific dnOrai1 Mice" |
9:20 pm - 9:30 pm | Discussion |
Sunday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | Understanding
Excitation-Contraction Coupling Through Disease Models |
| Discussion Leader: Johanna Lanner (Karolinska Institute, Sweden) |
9:00 am - 9:20 am | Donald Beqollari (University of Colorado, Denver, USA) "Progressive Impairment of CaV1.1 Function in Muscle of Mice Expressing a Mutant Cu/Zn Superoxide Dismutase 1 (SOD1 G93A)" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Johann Bohm (Institute of Genetics and Molecular and Cellular Biology, France) "Mutations in the SOCE Genes STIM1, ORAI1 and CASQ1 Cause Tubular Aggregate Myopathy (TAM)" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | James MacKrell (Eli Lilly & Company, USA) "Diet-Induced Vitamin D and/or Calcium Deficient Mice Exhibit Diminished Skeletal Muscle Function Attributable to Excitation-Contraction Uncoupling and Fiber Type Adaptations" |
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Bianca Vezzani (University of Siena, Italy) "Human Induced Pluripotent Stem Cells (hiPS) from Patients with a Vacuolar Myopathy as a Model to Study an Asp244Gly CASQ1 Mutation" |
10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship Component: Career Panel |
| Discussion Leaders: Anamika Dayal (Innsbruck Medical University, Austria) and James MacKrell (Eli Lilly & Company, USA) |
1:30 pm - 2:30 pm | Panel Discussion |
| "Career Development in Academia and Industry" |
|
- Roger Bannister (University of Colorado, Denver, USA)
- David Glass (Novartis Institutes for Biomedical Research, USA)
- Johanna Lanner (Karolinska Institute, Sweden)
|
2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
3:00 pm | Seminar Concludes |