| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 4:00 pm - 6:00 pm | Reception / Poster Mounting |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | INITIATION FACTORS FOR SKELETAL DEVELOPMENT AND DIFFERENTIATION |
| Discussion Leader: Sandell Linda, Washington University St. Louis,
St. Louis., MO, USA
Co-Discussion Leader: Kim Young-Jo, Children's Hospital, Boston, MA, USA |
| 7:30 pm - 8:10 pm | Lyons Karen, UCLA, Los Angeles, CA, USA
"Skeletal tissue formation and genetic regulation" |
| 8:10 pm - 8:50 pm | Fässler Reinhard, Max Planck Institute for Biochemistry, Martinsried/Munich, Germany
"Cell migration, adhesion and differentiation in skeletogenesis" |
| 8:50 pm - 9:30 pm | Yang Xiangli, Baylor College of Medicine, Houston, TX, USA
"Regulators in osteoblast differentiation and function" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | GROWTH FACTORS AND MECHANOREGULATION |
| Discussion Leader: Cancedda Ranieri, Laboratorio Differenziamento Cellulare, Genova, Italy |
| 9:00 am - 9:40 am | Grotendorst Gary R., University of Miami School of Medicine, Miami, FL, USA
"A structure/function analysis of CTGF regulation of proliferation and differentiation of connective tissue cells" |
| 9:40 am - 10:00 am | Selected presentations from poster session |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Salter Donald M., Edinburgh University Medical School, Edinburgh, U.K.
"Cytokine and neuropeptide involvement in human articular chondrocyte mechano-transduction" |
| 11:10 am - 11:50 am | Chen Qian, Pennsylvania State University College of Medicine, Hershey, PA, USA
"The role of Indian hedgehog in mechanical stress and cell proliferation" |
| 11:50 am - 12:30 pm | Selected presentations from poster session |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MOLECULAR MECHANICS AND SIGNAL TRANSDUCTION MECHANISMS |
| Discussion Leader: Grodzinsky Alan J., MIT, Cambridge, MA, USA |
| 7:30 pm - 8:10 pm | Ortiz Christine, MIT, Cambridge, MA, USA
"Nanomechanics of Cartilage: Direct Measurement of Glycosaminoglycan Intermolecular Interactions Via High-Resolution Force Spectroscopy" |
| 8:10 pm - 8:50 pm | Forgacs Gabor, Clarkson University, Potsdam, NY, USA
"The use of magnetic tweezers for the analysis of intracellular molecular rheology in mechanotransducted signaling throughout the cytoskeleton" |
| 8:50 pm - 9:30 pm | Selected presentations from poster session |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CELLULAR RESPONSES TO MECHANICAL STRESS |
| Discussion Leader: Chiquet Matthias, University of Bern, Bern, Switzerland |
| 9:00 am - 9:40 am | Felsenfeld Dan P., Mount Sinai School of Medicine, NY, USA
"Role of integrins in force transmission across the cell membrane" |
| 9:40 am -10:00 am | Selected presentations from poster session |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Gardner David G., University of California, San Francisco, CA, USA
"Mechanotransduction and gene activation in heart myocytes" |
| 11:10 am - 11:40 am | Shyy John Y.-J., University of California, Riverside, CA, USA
"Intracellular signaling in response to shear stress" |
| 11:40 am - 12:30 pm | Selected presentations from poster session |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | REGULATORY MECHANISMS IN TENDON AND LIGAMENT CELL BIOLOGY |
| Discussion Leader: Butler David L.. University of Cincinnati, Cincinnati, OH, USA |
| 7:30 pm - 8:10 pm | Aspenberg Per, University of Lund, Lund, Sweden
"Growth- and differentiation factors to augment tendon healing" |
| 8:10 pm - 8:50 pm | Mikic Borjana, Smith College, Northhampton, MA, USA
"GDF modulation of tendon maintenance and repair" |
| 8:50 pm - 9:30 pm | Frank Cyril B., University of Calgary, Calgary, Canada
"Biomechanics of ligament repair" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | GENETIC AND MECHANICAL FACTORS IN THE FORMATION OF CARTILAGE AND INTERVERTEBRAL DISC |
| Discussion Leader: Buschmann Michael, Ecole Polytechnique, Montreal, Canada
Co-Discussion Leader: Trippel Stephen B., Indiana University School of Medicine, Indianapolis, IN, USA |
| 9:00 am - 09:40 am | de Crombrugghe Benoit, University of Texas, Houston, TX, USA
"Genetic regulation of chondrogenesis" |
| 9:40 am - 10:00 am | Selected presentations from poster session |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Guilak Farshid, Duke University Medical Center, Durham, NC, USA
"Biomechanical regulation of chondrocyte signaling and function" |
| 11:10 am - 11:50 am | Lotz Jeffrey C., University of California, San Francisco, CA, USA
"Mechanical regulation of disc degeneration" |
| 11:50 am - 12:30 pm | Selected presentations from poster session |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MECHANOREGULATION OF BONE CELLS AND -STRUCTURE |
| Discussion Leader: Carter Dennis, Stanford University, Stanford, CA, USA
Co-Discussion Leader: Einhorn Thomas A., Boston Medical Center, Boston, MA, USA |
| 7:30 pm - 8:10 pm | Jacobs Christopher R., Stanford University, Stanford, CA, USA
"Physical signals regulating bone cells and their environment" |
| 8:10 pm - 8:50 pm | Helms Jill A., University of California, San Francisco, CA, USA
"Micromechanical regulation of fracture healing" |
| 8:50 pm - 9:30 pm | Selected presentations from poster session |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CELL-BASED TISSUE ENGINEERING FOR SKELETAL TISSUES |
| Discussion Leader: Vunjak-Novakovic Gordana, MIT, Cambridge, MA, USA |
| 9:00 am - 9:40 am | Martin Ivan, University of Basel, Basel, Switzerland
"Matrix scaffold properties for cell-based tissue engineering" |
| 9:40 am - 10:00 am | Selected presentations from poster session |
| 10:00 am | Coffee Break |
| 10:30 am - 11:10 am | Quarto Rodolfo, Laboratorio Differenziamento Cellulare, Genova, Italy
"Marrow-derived osteoprogenitor cells: Biology and therapeutic potential" |
| 11:10 am - 11:50 am | Jurvelin Jukka, Kuopio University Hospital, Kuopio, Finland
"In-vivo evaluation of engineered tissue responses" |
| 11:50 am - 12:30 pm | Selected presentations from poster session |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | HONORARY SPEAKER |
| Discussion Leader: Hunziker Ernst B., University of Bern, Bern, Switzerland |
| 7:30 pm - 9:00 pm | Fleisch Herbert, Bern, Switzerland
"Biphosphonates in bone disease - from a washing powder to a drug" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
