SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Translational Studies on Enhancing Soft Tissue Healing |
| Discussion Leader: Martha M. Murray (Harvard University) |
7:40 pm - 8:05 pm | Kathleen A. Derwin and Joseph P. Iannotti (Cleveland Clinic)
"Translational Studies in Rotator Cuff Healing"
|
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Helen H. Lu and William N. Levine (Columbia University)
"Insertion Site Healing / Tendon to Bone Healing"
|
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Richard H. Gelberman and Stavros Thomopoulos (Washington University at St. Louis)
"Flexor Tendons"
|
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Signaling and Regulation in Musculoskeletal Growth and Regeneration |
| Discussion Leader: Rocky S. Tuan (University of Pittsburgh) |
9:00 am - 9:20 am | Benjamin A. Alman (Hospital for Sick Children, Toronto)
"Molecular Regulation of Cartilage Growth"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Susan Mackem (National Cancer Institute)
"Early and Late Signals in Limb AP Patterning"
|
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:40 am | Scott Roberts (KU Leuven)
"Mapping Early Bone Formation Gene Networks Allows Targeted Osteoinduction of Human Periosteal Progenitors in vitro and in vivo"
|
10:40 am - 10:50 am | Discussion |
10:50 am - 11:10 am | Francis Lee (Columbia University)
"Proteomic Identification of a Novel Anti-Osteoclastogenic Protein"
|
11:10 am - 11:25 am | Discussion |
11:25 am - 11:35 am | Jonathan Schoenecker (Vanderbilt University)
"Fibrinolysis - The Fountain of Youth of Bone?"
|
11:35 am - 11:45 am | Discussion |
11:45 am - 11:55 am | Jenna Galloway (Harvard University)
"Small Molecule Screening in Zebrafish for Regulators of Tendon Development"
|
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | Open Discussion on Signaling and Regulation in Musculoskeletal Growth and Regeneration |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Knee Kinematics, Injury Prevention and Rehabilitation |
| Discussion Leader: Braden C. Fleming (Brown University) |
7:30 pm - 7:45 pm | Timothy E. Hewett (Ohio State University and University of Cincinnati)
"Injury Prevention"
|
7:45 pm - 7:55 pm | Discussion |
7:55 pm - 8:10 pm | Thomas P. Andriacchi (Stanford University)
"Kinematic ACL Injury and OA"
|
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:35 pm | Lynn Snyder-Mackler (University of Delaware)
"Defining the Coper - Which ACL Tears Need Surgery?"
|
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:00 pm | Scott Tashman (University of Pittsburgh)
"Dynamic Function of the Cruciate Ligament Injured Knee"
|
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Louis E. DeFrate (Duke University)
"Graft Placement in Ligament Reconstruction"
|
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Mechanobiology |
| Discussion Leader: Robert Sah (University of California-San Diego) |
9:00 am - 9:20 am | Gregory D. Jay (Brown University)
"Lubrication of Synovial Joints"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Jill Urban (Oxford University)
"Intervertebral Disk"
|
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Robert L. Mauck (McKay Lab, University of Pennsylvania)
"Meniscus"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | X. Edward Guo (Columbia University)
"Bone Mechanobiology" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:40 am | Carolyn Hettrich (University of Iowa)
"The Effect of Mechanical Load on Tendon to Bone Healing in a Rat Model"
|
11:40 am - 11:45 am | Discussion |
11:45 am - 12:00 pm | Matthew Fisher (University of Pennsylvania)
"Trajectory-based Tissue Engineering for Cartilage Repair: Development of In-Vitro and In-Vivo Models"
|
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | Open Discussion on Mechanobiology |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Functional Tissue Engineering |
| Discussion Leader: Lisa A. Fortier (Cornell University) |
7:30 pm - 7:55 pm | Wiltrud Richter (Stiftung Orthopädische Universitätsklinic Heidelberg)
"Functional Correlates of Donor-dependency of Bone Formation in Human Mesenchymal Stem Cell"
|
7:55 pm - 8:10 pm | Discussion |
8:10 pm - 8:35 pm | Gerjo van Osch (Erasmus MC, University Medical Center, Rotterdam)
"Cartilage Repair in a Diseased Joint"
|
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Jeremy J. Mao (Columbia University)
"Recruitment of Endogenous Stem Cells for Musculoskeletal Tissue Regeneration"
|
9:15 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Stem Cells in Health and Injury |
| Discussion Leader: Johnny Huard (University of Pittsburgh) |
9:00 am - 9:20 am | Bruno Péault (University of Edinburgh and UCLA)
"Muscle"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Diego Correa (Case Western Reserve University)
"MSC, a Perivascular Cell with Various Roles in Health and Disease" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Jennifer Elisseeff (Johns Hopkins University)
"Stem Cells, Embryonic Stem Cells"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:10 am | Michael Hoffman (University of Rochester)
"Mesenchymal Stem Cell (MSC) Persistence via Degradable Hydrogel Periosteum Mimetics Promotes Allograft Revitalization"
|
11:10 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Roshni Rainbow (Tufts University)
"Muscle-derived Factors Enhance the Stability of Human MSC-derived Chondrocytes under Inflammatory Conditions"
|
11:30 am - 11:40 am | Discussion |
11:40 am - 11:50 am | Wai Ming Anthony Cheng (University of Pittsburgh)
"Co-culturing with MSCs in vitro Alters Early Post-traumatic Catabolic and Inflammatory Responses in Mechanically Injured Articular Cartilage"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Open Discussion on Stem Cells in Health and Injury |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:25 pm | Tendon Adhesions |
7:30 pm - 7:40 pm | Discussion Leader: Peter C. Amadio (Mayo Clinic)
"Clinical Problems and Basic Biology" |
7:40 pm - 8:00 pm | Chunfeng Zhao (Mayo Clinic)
"Tissue Engineering Solutions"
|
8:10 pm - 8:25 pm | Discussion |
8:25 pm - 9:30 pm | Tendon End to End Healing |
8:25 pm - 8:32 pm | Jin Bo Tang (Affiliated Hospital of Nantong University, Jiangsu, China)
"Clinical Problems and Basic Biology"
|
8:32 pm - 8:35 pm | Discussion |
8:35 pm - 8:45 pm | Elizabeth Loboa (North Carolina State and University of North Carolina)
"Tissue Engineering Using Stem Cells"
|
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:00 pm | Jin Bo Tang (Affiliated Hospital of Nantong University, Jiangsu, China)
"Tissue Engineering Using Growth Factors"
|
9:00 pm - 9:05 pm | Discussion |
9:05 pm - 9:20 pm | Peter C. Amadio (Mayo Clinic)
"Outcomes at Bedside"
|
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
9:00 am - 12:30 pm | Cartilage and Osteoarthritis |
| Discussion Leader: Linda J. Sandell (Washington University at St. Louis) |
9:00 am - 9:20 am | Cosimo De Bari (University of Aberdeen)
"MSCs for Cartilage Repair" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Yves Henrotin (University of Liège, Belgium)
"Novel Biomarkers of Cartilage Degeneration" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Constance R. Chu (University of Pittsburgh)
"Imaging Biomarkers and Post-traumatic OA" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:10 am | Toran Macleod (UC-San Francisco)
"Effects of Meniscectomy on Knee Articular Cartilage T1rho and T2"
|
11:10 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Tannin Schmidt (University of Calgary)
"Cartilage Boundary Lubricating Ability of Full-Length Recombinant human PRG4 - Alone and in Combination with Hyaluronan"
|
11:30 am - 11:40 am | Discussion |
11:40 am - 11:50 am | Tim Griffin (Oklahoma Medical Research Foundation)
"Biomechanical Mediators of Endogenous Cartilage Antioxidant Activity: Cyclic Loading Preconditions Against Oxidative and Inflammatory Stress"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:30 pm | Open Discussion on Biomarkers |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session |
| Discussion Leader: TBA |
7:30 pm - 8:15 pm | Steven A. Goldstein (University of Michigan)
"Evolution of Musculoskeletal Research and Insights into the Future" |
8:15 pm - 8:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |